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Non-invasive method of determining skin thickness and characterizing layers of skin tissue in vivo

  • US 6,671,542 B2
  • Filed: 09/05/2002
  • Issued: 12/30/2003
  • Est. Priority Date: 02/25/2000
  • Status: Expired due to Term
First Claim
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1. A non-invasive method of estimating thickness of in vivo skin tissue and characterizing constituents of tissue Iayers, comprising the steps of:

  • measuring a NIR absorbance spectrum of a target layer at a tissue sample site;

    processing said measured NIR absorbance spectrum to enhance a signal of a plurality of key indicators;

    calculating a magnitude or a relative magnitude of at least one of said key indicators in said measured spectrum; and

    applying at least one calibration model to said calculated magnitude or relative magnitude to characterize said tissue layers.

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