Method and system for myocardial infarction repair
First Claim
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1. An implantable system comprising:
- (a) a differentiated cell repopulation source, optionally containing genetic material, capable of forming new contractile tissue in and/or near damaged or diseased myocardial tissue; and
(b) an electrical stimulation device for electrically stimulating the new contractile tissue in and/or near the damaged or diseased myocardial tissue.
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Abstract
An implantable system is provided that includes: a cell repopulation source comprising genetic material, undifferentiated and/or differentiated contractile cells, or a combination thereof capable of forming new contractile tissue in and/or near an infarct zone of a patient'"'"'s myocardium; and an electrical stimulation device for electrically stimulating the new contractile tissue in and/or near the infarct zone of the patient'"'"'s myocardium or otherwise damaged or diseased myocardial tissue.
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Citations
51 Claims
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1. An implantable system comprising:
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(a) a differentiated cell repopulation source, optionally containing genetic material, capable of forming new contractile tissue in and/or near damaged or diseased myocardial tissue; and
(b) an electrical stimulation device for electrically stimulating the new contractile tissue in and/or near the damaged or diseased myocardial tissue. - View Dependent Claims (6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51)
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2. Repair of the heart myocardium with an implantable system comprising:
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(a) a differentiated cell repopulation source, optionally containing genetic material, capable of forming new contractile tissue in and/or near damaged or diseased myocardial tissue; and
(b) an electrical stimulation device for electrically stimulating the new contractile tissue in and/or near the damaged or diseased myocardial tissue.
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3. A method of repairing the heart myocardium, the method comprising:
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(a) providing an implantable system comprising;
(i) a cell repopulation source comprising differentiated cells, optionally containing genetic material, capable of forming new contractile tissue in and/or near an infarct zone of a patient'"'"'s myocardium; and
(ii) an electrical stimulation device for electrically stimulating the new contractile tissue in and/or near the infarct zone of the patient'"'"'s myocardium;
(b) implanting the cell repopulation source into and/or near damaged or diseased myocardial tissue; and
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(c) electrically stimulating the new contractile tissue with an implanted electrical stimulation device. - View Dependent Claims (4, 5)
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Specification