Diagnostic ultrasound imaging based on rate subtraction imaging (RSI)

• US 6,673,019 B2
• Filed: 01/31/2001
• Issued: 01/06/2004
• Est. Priority Date: 01/31/2000
• Status: Expired due to Term

• Current Assignee: Toshiba Medical Systems Corporation (Canon Inc.)
• Original Assignee: Kabushiki Kaisha Toshiba (Toshiba Corporation)
• Inventors: Kamiyama, Naohisa
• Primary Examiner(s): Jaworski, Francis J.
• Application Number:
  US09/772,900
• Publication Number:
  US 20020028994A1
• Time in Patent Office: 1,070 Days
• Field of Search: 600/443, 600/447, 600/458, 600/437
• US Class Current: 600/443
• CPC Class Codes: A61B 8/463 characterised by displaying multiple images or images and diagnostic data on one display composite display in devices for short-range imaging with acoustic waves G01S7/52074
• CPC Class Codes: A61B 8/481 involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream analysis of echo signal exploiting properties of a contrast enhancer in devices for short-range imaging with acoustic waves G01S7/52039
• CPC Class Codes: G01S 7/52038 involving non-linear properties of the propagation medium or of the reflective target
• CPC Class Codes: G01S 7/52074 Composite displays, e.g. split-screen displays; Combination of multiple images or of images and alphanumeric tabular information
• CPC Class Codes: G01S 7/52085 Details related to the ultrasound signal acquisition, e.g. scan sequences control of medical diagnostic ultrasound devices A61B8/54

Abstract

In a diagnostic ultrasound apparatus, an ultrasound pulse signal is transmitted two times in each of the rasters on a region to be scanned. Subtraction between echo signals received at each time of transmission is made to obtain a difference signal. Either one of the echo signals and the difference signal are produced into individual tomographic images, independently of each other. The produced individual tomographic images are displayed with a superposed manner one on the other or parallel-arranged manner. This allows contrast echo imaging to be conducted on a rate subtraction imaging technique. Minute blood flows are depicted distinguishably from tissue surrounding those flows in a steady manner.

Claims

1. A diagnostic ultrasound apparatus for obtaining an image of a region to be scanned by scanning an object with a beam-shaped ultrasound signal produced as a radio frequency signal, an ultrasound contrast agent being injected into the object, the apparatus comprising:

a scanning unit configured to transmit the ultrasound signal a plurality of times in each scanning direction along the region to be scanned and receiving an echo signal generated from the object in response to each time of transmission of the ultrasound signal in each scanning direction;

a subtracting unit configured to obtain a difference signal by performing subtraction between first and second echo signals each still being the radio frequency signal, the first and second echo signals being from the plurality of echo signals received in response to the transmission of the ultrasound signal in the same scanning direction;

a producing unit configured to produce the difference signal into a first tomographic imageby a rate subtraction imaging technique using first processing conditions and to produce either the first or second echo signal into a second tomographic image using second processing conditions different from the first processing conditions; and

a displaying unit configured to display both the first and second tomographic images at the same time.

2. The diagnostic ultrasound apparatus of claim 1, wherein the plurality of times of transmission is two times of transmission along each scanning direction.

3. The diagnostic ultrasound apparatus of claim 2, wherein the processing conditions include at least one of a reception gain, a dynamic range, a cut-off frequency and a bandwidth of an echo filter, and a frame-to-frame after-image processing, which are used in the producing unit.

4. The diagnostic ultrasound apparatus of claim 2, wherein the processing conditions include information indicating at least one of a correction processing technique and a color encoding technique performed when intensities of the echo signals are mapped for display by the displaying unit.

5. The diagnostic ultrasound apparatus of claim 1, wherein the displaying unit has means for displaying the first and second tomographic images in mutually different colors.

6. The diagnostic ultrasound apparatus of claim 1, wherein the displaying unit has means for displaying the first and second tomographic images on a superposition basis one on another.

7. The diagnostic ultrasound apparatus of claim 6, wherein the displaying unit has means for displaying one tomographic image based on the difference signal superposed on the other tomographic image based on either the first or second echo signal.

8. The diagnostic ultrasound apparatus of claim 7, wherein the displaying unit has means for displaying either one of the first and second tomographic images in gray scales and a remaining tomographic image in colors.

9. The diagnostic ultrasound apparatus of claim 7, wherein the displaying unit has means for displaying the one and other tomographic images in mutually different colors.

10. The diagnostic ultrasound apparatus of claim 7, wherein the displaying unit has superposition control means changeable in a superposition balance of intensity of the first and second tomographic images displayed on the superposition basis.

11. The diagnostic ultrasound apparatus of claim 10, wherein the superposition control unit has manual-change commanding means capable of manually changing the superposition balance.

12. The diagnostic ultrasound apparatus of claim 1, wherein the displaying unit has means for displaying the first and second tomographic images in parallel with each other.

13. The diagnostic ultrasound apparatus of claim 1, wherein the producing unit has image memorizing means capable of individually memorizing image data of the first and second tomographic images and individually reading out the image data thereof.

14. The diagnostic ultrasound apparatus of claim 13, wherein the displaying unit has means for individually reading out the image data of the first and second tomographic images from the image memorizing means, and means for commanding a switchover of display modes consisting of superposed display of the first and second tomographic images, parallel display of the first and second tomographic images, and sole display of either one of the first and second tomographic images on the bases on the read-out image data.

15. The diagnostic ultrasound apparatus of claim 14, wherein the displaying unit includes means for independently selecting at least one of a correction processing technique and a color encoding technique in accordance with which of the echo signal and the difference signal corresponds to the read-out image data and means for mapping the image data on a video screen based on the selected technique.

16. The diagnostic ultrasound apparatus of claim 1, wherein the ultrasound contrast agent is a contrast agent of which main constituent is microbubbles, and the scanning unit has means for additionally transmitting an ultrasound signal to excite the microbubbles in each scanning direction.

17. The diagnostic ultrasound apparatus of claim 1, wherein the additional transmission of the exciting ultrasound signal interleaves in time between the two times of transmission of the ultrasound signal.

18. The diagnostic ultrasound apparatus of claim 1, wherein the displaying unit has means for commanding a switchover of display modes consisting of superposed display of the first and second tomographic images, parallel display of the first and second tomographic, and sole display of either one of the first and second tomographic images.

19. The diagnostic ultrasound apparatus of claim 1, wherein the producing unit includes a receiver in which detection is carried out toward the echo signals, wherein

the ultrasound signal to be transmitted is formed into the radio frequency signal and the echo signal experiencing the subtraction executed by the subtraction unit is an echoed signal of the radio frequency signal which has yet to be subjected to the detection in the receiver.

20. The diagnostic ultrasound apparatus of claim 1, wherein scanning unit is configured to successively transmit the ultrasound signal the plurality of times in each scanning direction.

21. A diagnostic ultrasound apparatus for obtaining an image of a region to be scanned by scanning an object with a beam-shaped ultrasound signal produced as a radio frequency signal, an ultrasound contrast agent being injected into the object, the apparatus comprising:

a scanning unit configured to transmit the ultrasound signal a plurality of times in each scanning direction along the region to be scanned and to receive an echo signal generated from the object in response to each time of transmission of the ultrasound signal in each scanning direction;

a subtracting unit configured to obtain a difference signal by performing subtraction between first and second echo signals each still being the radio frequency signal, the first and second echo signals being from the plurality of echo signals received in response to the transmission of the ultrasound signal mt he same scanning direction;

an adding unit configured to obtain an average signal by performing average between the first and second echo signals;

a producing unit configured to produce the difference signal into a first tomographic image by a rate subtraction imaging technique and to produce the average signal into a second tomographic image; and

a displaying unit configured to display both the first and second tomographic images at the same time.

22. The diagnostic ultrasound apparatus of claim 21, wherein the plurality of times of transmission is two times of transmission along each scanning direction.

23. The diagnostic ultrasound apparatus of claim 22, wherein the producing unit includes processing means for processing, into image data of the first and second tomographic images, the average signal and the difference signal under processing conditions mutually independent of each other.

24. The diagnostic ultrasound apparatus of claim 21, wherein the displaying unit has means for displaying the first and second tomographic images in either a superposition manner or a parallel manner.

25. The diagnostic ultrasound apparatus of claim 21, wherein the subtracting unit has means for performing the subtraction between the first echo signal received in response to the first transmission of the plurality of times of transmission of the ultrasound signal along each scanning line and the second echo signal received in response to a transmission carried out after the first transmission of the plurality of times of transmission of the ultrasound signal along each scanning line, and

the adding unit has means for performing the addition between the first echo signal received in response to the first transmission of the plurality of times of transmission of the ultrasound signal along each scanning line and the second echo signal received in response to a transmission carried out after the first transmission of the plurality of times of transmission of the ultrasound signal along each scanning line.

26. The diagnostic ultrasound apparatus of claim 21, wherein scanning unit is configured to successively transmit the ultrasound signal the plurality of times in each scanning direction.

27. An ultrasound imaging method of obtaining an image of a region to be scanned by scanning an object with a beam-shaped ultrasound signal produced as a radio frequency signal, an ultrasound contrast agent being injected into the object, comprising the steps of:

transmitting the ultrasound signal a plurality of times in each scanning direction along the region to be scanned and receiving an echo signal generated from the object in response to each time of transmission of the ultrasound signal in each scanning direction;

obtaining a difference signal by performing subtraction between first and second echo signals each still being the radio frequency signal, the first and second echo signals being from the plurality of echo signals received in response to the transmission of the ultrasound signal in the same scanning direction;

producing the difference signal into a first tomographic image by a rate subtraction imaging technique using first processing conditions and producing either the first or second echo signal into a second tomographic image using second processing conditions different from the first processing conditions; and

displaying both the first and second tomographic images at the same time.

28. The ultrasound imaging method of claim 27, wherein in the transmitting step, the ultrasound is successively transmitted the plurality of times in each scanning direction.

29. An ultrasound imaging method of obtaining an image of a region to be scanned by scanning an object with a beam-shaped ultrasound signal produced as a radio frequency signal, an ultrasound contrast agent being injected into the object, comprising the steps of:

transmitting the ultrasound signal a plurality of times in each scanning direction along the region to be scanned and receiving an echo signal generated from the object in response to each time of transmission of the ultrasound signal in each scanning direction;

calculating a difference signal by performing subtraction between first and second echo signals each still being the radio frequency signal and calculating an average signal by performing average between the first and second echo signals, the first and second echo signals being from the plurality of echo signals received in response to the transmission of the ultrasound signal in the same scanning direction;

producing the difference signal into a first tomographic image by a rate subtraction imaging technique and producing the average signal into a second tomographic image; and

displaying both the first and second tomographic images at the same time.

30. The ultrasound imaging method of claim 29, wherein in the transmitting step, the ultrasound signal is successively transmitted the plurality of times in each scanning direction.

31. A diagnostic ultrasound apparatus for obtaining an image of a region to be scanned by scanning an object with a beam-shaped ultrasound signal produced as a radio frequency signal, an ultrasound contrast agent being injected into the object, the apparatus comprising:

an ultrasound probe configured to transmit and receive the ultrasound signal;

a transmitter configured to excite the ultrasound probe responsively to each of a plurality of rate pulses so as to cause the ultrasound probe to output the ultrasound signal;

a receiver configured to delay and add an echo signal received by the ultrasound probe;

a controller configured to cause the transmitter to transmit the ultrasound signal a plurality of times in each scanning direction along the region to be scanned and to cause the receiver to receive the echo signal generated from the object in response to each of the plurality of times of transmission of the ultrasound signal in each scanning direction;

a subtracter configured to obtain a difference signal by performing subtraction between first and second echo signals each still being the radio frequency signal, the first and second echo signals being from the plurality of echo signals received in response to the transmission of the ultrasound signal in the same scanning direction;

a producer configured to produce the difference signal into a first tomographic image by a rate subtraction imaging technique using first processing conditions and to produce either the first or second echo signal into a second tomographic image using second processing conditions different from the first processing conditions; and

a display configured to display both the first and second tomographic images at the same time.

32. The diagnostic ultrasound apparatus of claim 31, wherein the plurality of times of transmission is two times of transmission along each scanning direction.

33. The diagnostic ultrasound apparatus of claim 31, wherein the display is configured to display the first and second tomographic images on a superposition basis one on another.

34. The diagnostic ultrasound apparatus of claim 33, wherein the display is configured to be changeable in a superposition balance of intensity of the first and second tomographic images displayed on the superposition basis.

35. The diagnostic ultrasound apparatus of claim 34, wherein the display is configured to be capable of manually changing the superposition balance.

36. The diagnostic ultrasound apparatus of claim 31, wherein the ultrasound signal to be transmitted is formed into the radio frequency signal and the echo signal experiencing the subtraction executed by the subtracter is an echoed signal of the radio frequency signal which has yet to be subjected to detection carried out in the receiver.

37. A diagnostic ultrasound apparatus for obtaining an image of a region to be scanned by scanning an object with a beam-shaped ultrasound signal produced as a radio frequency signal, an ultrasound contrast agent being injected into the object, the apparatus comprising:

scanning means for transmitting the ultrasound signal a plurality of times in each scanning direction along the region and receiving an echo signal generated from the object in response to each time of transmission of the ultrasound signal in each scanning direction;

subtracting means for obtaining a difference signal by performing subtraction between first and second echo signals each still being the radio frequency signal, the first and second echo signals being from the plurality of echo signals received in response to the transmission of the ultrasound signal in the same scanning direction;

producing means for producing the difference signal into a first tomographic image by a rate subtraction imaging technique using first processing conditions and for producing either the first or second echo signal into a second tomographic image using second processing conditions different from the first processing conditions; and

displaying means for displaying both the first and second tomographic images at the same time.

38. A diagnostic ultrasound apparatus for obtaining an image of a region to be scanned by scanning an object with a beam-shaped ultrasound signal produced as a radio frequency signal, an ultrasound contrast agent being injected into the object, the apparatus comprising:

scanning means for transmitting the ultrasound signal a plurality of times in each scanning direction along the region and receiving an echo signal generated from the object in response to each time of transmission of the ultrasound signal in each scanning direction;

subtracting means for obtaining a difference signal by performing subtraction between first and second echo signals each still being the radio frequency signal, the first and second echo signals being from the plurality of echo signals received in response to the transmission of the ultrasound signal in the same scanning direction;

addition means for obtaining an average signal by performing average between the first and second echo signals;

producing mean for producing the difference signal into a first tomographic image by a rate subtraction imaging technique and producing the average signal into a second tomographic image; and

displaying means for displaying both the first and second tomographic images at the same time.