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Coagulation or lysis assays by measuring impedance

  • US 6,673,622 B1
  • Filed: 01/15/1999
  • Issued: 01/06/2004
  • Est. Priority Date: 06/27/1997
  • Status: Expired due to Term
First Claim
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1. A device for performing a coagulation or lysis assay of a sample, the device comprising:

  • a housing having an exterior surface and defining an interior area;

    means for receiving the sample through the housing into the interior area;

    a non-porous substrate positioned within the interior area for receiving the sample;

    a reagent for accelerating the coagulation of the sample in the housing and contact with the sample;

    means for measuring the impedance of the sample and generating a signal which correlates to a curve of the coagulation or lysis assay; and

    processing means being positioned within the interior area and connected to the measuring means for receiving and converting the signal into an output external to the housing corresponding to the coagulation or lysis assay using assay calibration information stored in the device.

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