Tissue specimen isolating and damaging device and method

• US 6,676,658 B2
• Filed: 06/18/2001
• Issued: 01/13/2004
• Est. Priority Date: 04/08/1998
• Status: Expired due to Term

• Current Assignee: Senorx Incorporated (Becton, Dickinson & Co)
• Original Assignee: Senorx Incorporated (Becton, Dickinson & Co)
• Inventors: Burbank, Fred H., Lubock, Paul
• Primary Examiner(s): PEFFLEY, MICHAEL F
• Application Number:
  US09/884,349
• Publication Number:
  US 20010039420A1
• Time in Patent Office: 939 Days
• Field of Search: 606/37-42, 606/45-50, 600/564-567
• US Class Current: 606/45
• CPC Class Codes: A61B 10/0041 Detection of breast cancer mammography by transillumination A61B5/0091, by X-rays A61B6/502, by ultrasonic means A61B8/0825
• CPC Class Codes: A61B 10/02 Instruments for taking cell samples or for biopsy A61B10/0038 and A61B10/0045 take precedence; needle locating or guiding means A61B17/3403; samplers for enzymology or microbiology C12M1/26; sampling or preparing biological specimens G01N33/48
• CPC Class Codes: A61B 10/0233 Pointed or sharp biopsy instruments
• CPC Class Codes: A61B 10/0266 means for severing sample
• CPC Class Codes: A61B 17/00234 for minimally invasive surgery A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/32056 Surgical snare instruments for removing or smashing calculi A61B2017/2212; tonsillotomes A61B17/26
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 17/3417 Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating syringe needles A61M5/32; dilators A61M29/00
• CPC Class Codes: A61B 18/0206 ultrasonic, e.g. for destroying tissue or enhancing freezing
• CPC Class Codes: A61B 18/06 caused by chemical reaction , e.g. moxaburners
• CPC Class Codes: A61B 18/14 Probes or electrodes therefor
• CPC Class Codes: A61B 18/148 having a short, rigid shaft for accessing the inner body transcutaneously, e.g. for neurosurgery or arthroscopy
• CPC Class Codes: A61B 18/1482 having a long rigid shaft for accessing the inner body transcutaneously in minimal invasive surgery, e.g. laparoscopy
• CPC Class Codes: A61B 18/1487 Trocar-like, i.e. devices producing an enlarged transcutaneous opening
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/20 using laser
• CPC Class Codes: A61B 2010/0208 Biopsy devices with actuators, e.g. with triggered spring mechanisms
• CPC Class Codes: A61B 2017/00287 Bags for minimally invasive surgery
• CPC Class Codes: A61B 2017/2212 : having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/320733 : with a flexible cutting or scraping element, e.g. with a whip-like distal filament member
• CPC Class Codes: A61B 2017/3488 : Fixation to inner organ or inner body tissue
• CPC Class Codes: A61B 2018/00208 : actively driven, e.g. by a motor
• CPC Class Codes: A61B 2018/00214 : Expandable means emitting energy, e.g. by elements carried thereon
• CPC Class Codes: A61B 2018/00267 : having a basket shaped structure
• CPC Class Codes: A61B 2018/00333 : Breast
• CPC Class Codes: A61B 2018/00577 : Ablation
• CPC Class Codes: A61B 2018/00601 : Cutting
• CPC Class Codes: A61B 2018/00898 : Alarms or notifications created in response to an abnormal condition
• CPC Class Codes: A61B 2018/0091 : Handpieces of the surgical instrument or device
• CPC Class Codes: A61B 2018/00916 : with means for switching or controlling the main function of the instrument or device
• CPC Class Codes: A61B 2018/1253 : monopolar
• CPC Class Codes: A61B 2018/126 : bipolar
• CPC Class Codes: A61B 2018/1407 : Loop
• CPC Class Codes: A61B 2018/1425 : Needle
• CPC Class Codes: A61B 2018/144 : Wire
• CPC Class Codes: A61B 2018/1475 : Electrodes retractable in or deployable from a housing
• CPC Class Codes: A61B 2018/162 : located on the probe body
• CPC Class Codes: A61B 2018/1861 : with an instrument inserted into a body lumen or cavity, e.g. a catheter
• CPC Class Codes: A61B 2090/3908 : Soft tissue, e.g. breast tissue
• CPC Class Codes: A61B 90/37 : Surgical systems with images on a monitor during operation
• CPC Class Codes: A61N 5/1007 : Arrangements or means for the introduction of sources into the body
• CPC Class Codes: A61N 5/1027 : Interstitial radiation therapy

Abstract

A device and method for treatment of a tissue specimen disposed in surrounding tissue has a tissue specimen isolating tool and a tissue specimen damager. The tissue specimen isolating tool isolates the tissue specimen from the surrounding tissue. The tissue specimen damager damages the tissue, with a possible end result being necrosis. The severing tool may have a cutting member that is extendable to an outwardly radially bowed position about device. The tissue specimen is isolated by rotating the cutting member about the tissue specimen. The cutting member may be functionally connected to a cutting member radio frequency generation source. The tissue specimen damager may damage the tissue specimen using ionizing radiation, cutting devices, thermal treatment devices, chemical treatment devices, or sealing an outer boundary of the tissue specimen.

Claims

1. A device for isolating and damaging a tissue specimen comprising:

an elongate shaft having a longitudinal axis and a distal portion having a distal end;

a tissue cutting element which is disposed on the elongate distal portion of the shaft proximal to the distal end and which is configured to at least partially isolate a desired tissue specimen from surrounding tissue at the tissue site by defining a peripheral margin about the tissue specimen; and

a tissue specimen damager which is on the distal portion of the shaft and which is configured to engage and damage the isolated tissue specimen in situ at the tissue site.

2. The device of claim 1, wherein the tissue specimen damager is selected from the group consisting of at least one metal member functionally connected to a source of radio frequency power, an ionizing radiation director, a mechanical tissue specimen damager, a thermal treatment system, and a chemical introduction system.

3. The device of claim 2, wherein the tissue specimen damager is formed of at least one radiofrequency wire configured to extend from a proximal portion of the shaft.

4. The device of claim 3, wherein the device is configured effective that the radiofrequency wire is retractable from an extended position and that the radiofrequency wire is extendable from a retracted position.

5. The device of claim 2, wherein the tissue specimen damager includes an ionizing radiation director comprising a source of ionizing radiation selected from the group consisting of x-ray sources, gamma ray sources, brachytherapy seeds, and combinations thereof.

6. The device of claim 2, wherein the tissue specimen damager includes a mechanical tissue specimen damager selected from the group consisting of morcellators and cutters.

7. The device of claim 6, wherein the tissue specimen damager is a morcellator.

8. The device of claim 2, wherein the tissue specimen damager includes a source of thermal energy for thermal treatment selected from the group consisting of lasers, hot fluids, cold fluids, radiofrequency energy, microwave energy, focused ultrasound, mechanical ultrasound, shock waves, resistive heating, cryosurgery, cauterizers, heated objects, and combinations thereof.

9. The device of claim 2, wherein the tissue specimen damager includes a chemical introduction system effective to introduce a tissue-damaging chemical selected from the group consisting of ethanol, sotradechol, acids, bases, chemical compounds, chemical mixtures, photoreactive chemicals, and sealers.

10. The device of claim 1 wherein an encapsulation member is provided which is configured to extend about the isolated tissue specimen.