Multi-layered dressing

• US 6,680,113 B1
• Filed: 02/10/2000
• Issued: 01/20/2004
• Est. Priority Date: 12/29/1989
• Status: Expired due to Fees

• Current Assignee: 3M Innovative Properties Company (3M Company)
• Original Assignee: 3M Innovative Properties Company (3M Company)
• Inventors: Heinecke, Steven B., Lucast, Donald H.
• Primary Examiner(s): ZIRKER, DANIEL R
• Application Number:
  US09/501,435
• Time in Patent Office: 1,440 Days
• Field of Search: 428/354, 428/343, 602/54, 602/55, 602/903
• US Class Current: 428/354
• CPC Class Codes: A61F 13/023 wound covering film layers without a fluid retention layer
• CPC Class Codes: Y10S 602/903 Surgical tape
• CPC Class Codes: Y10T 428/28 Web or sheet containing structurally defined element or component and having an adhesive outermost layer
• CPC Class Codes: Y10T 428/2848 Three or more layers

Abstract

A highly moisture vapor transmissive adhesive composite is disclosed comprising at least three layers, a polymeric backing layer, a high moisture vapor transmission layer, and a skin contacting adhesive layer. The high moisture vapor transmission layer may be made from a polymeric backing material, an adhesive material or both.

Claims

1. An adhesive composite comprising

a) a polymeric backing layer that is liquid and bacteria impermeable,

b) a high moisture vapor transmission layer comprising a gel-adhesive mixture composition that comprises a pressure-sensitive adhesive, a hydrocolloid, and a liquid swelling agent, and

c) a skin contacting adhesive layer, and wherein said high moisture vapor transmission layer is selected from an adhesive material having a Standardized Transmission Rate of at least 900 g/m²/24hrs/37°

C./100-20% RH, and the skin contacting adhesive layer is selected from an adhesive material having an adhesion to skin strength of a least 15 g/in., provided that the material of layer b) is not the same as the material of layer c) and that the overall adhesive composite exhibits a moisture vapor transmission rate of at least about 1200 g/m²/24 hrs/37°

C./20% RH.

2. The adhesive composite of claim 1 wherein the overall adhesive composite has a moisture vapor transmission rate that is greater than about 1500 g/m²/24 hrs/37°

C./100-20% RH as tested using the Upright Cup method.

3. The adhesive composite of claim 1 wherein the overall adhesive composite has a moisture vapor transmission rate that is greater than about 2000 g/m²/24 hrs/37°

C./100-20% RH as tested using the Upright Cup method.

4. The adhesive composite of claim 1 wherein the overall adhesive composite has a moisture vapor transmission rate that is greater than about 2500 g/m²/24 hrs/37°

C./100-20% RH as tested using the Upright Cup method.

5. The adhesive composite of claim 1 wherein the polymeric backing layer is between about ⅓

to {fraction (1/20)}th of the thickness of said high moisture transmission layer.

6. The adhesive composite of claim 1 wherein the polymeric backing layer is between about ⅕

to {fraction (1/10)}th of the thickness of said high moisture transmission layer.

7. The adhesive composite of claim 1 wherein the contacting adhesive layer is between about ⅓

to {fraction (1/20)}th of the thickness of said high moisture transmission layer.

8. The adhesive composite of claim 1 wherein the contacting adhesive layer is between about ⅕

to {fraction (1/10)}th of the thickness of said high moisture transmission layer.

9. The adhesive composite of claim 1 wherein said moisture vapor transmission layer is an adhesive composition comprising n-butyl acrylate, N-vinyl pyrrolidone, alkoxy polyethylene oxide acrylate and iso-octyl acrylate.

10. The adhesive composite of claim 1 wherein said skin contacting adhesive layer is pattern coated.

11. The adhesive composite of claim 1, wherein said high moisture transmission layer has a standardized transmission rate of greater than about 1100 g/m²/24 hrs/37°

C./100-20% RH.

12. The adhesive composite of claim 1, wherein said high moisture transmission layer has a standardized transmission rate of greater than about 1400 g/m²/24 hrs/37°

C./100-20% RH.

13. The adhesive composite of claim 1, wherein said hydrocolloid is selected from the group consisting of acrylate polymers having hydroxy or amine functionalities, poly (N-vinyl lactams), polyacrylamides, polysaccarides, natural and synthetically modified alginates, guar gums, natural and synthetically modified celluloses, chitosan, chitin, polyoxyalkylenes, and polyvinyl alcohols.

14. The adhesive composite of claim 1, wherein said swelling agent comprises room temperature liquid polyols selected from the group consisting of glycerol, propylene glycol, poly(ethylene) glycol , polypropylene glycol, and combinations thereof.

15. The adhesive composite of claim 1, wherein said swelling comprises room temperature liquid polyols blended with room temperature solid polyols selected from the group consisting of sorbitol, erthyritol, threitol, ribotol, arabinitol, xylitol, allitol, talitol, mannitol, glucitol, glactitol, iditiol, pentaerythritol, heptitol, octitol, nonitol, decitol, and dodenitol.

16. The adhesive composite of claim 1, wherein the range of weight fraction ratios for the hydrocolloid to the swelling agent is from about 3:

1 to about 1;

99.

17. The adhesive composite of claim 1, wherein the scar modulus of the gel-adhesive is less than 6.2×

10(6) dynes/cm(2).

18. The adhesive composite of claim 1, wherein the overall profile of the composite does not exceed about 0.5 mm.

19. The adhesive composite of claim 1, wherein the overall profile of the composite does not exceed about 0.2 mm.

20. The adhesive composite of claim 1, wherein the overall profile of the composite does not exceed about 0.05 mm.

21. The adhesive composite of claim 1, wherein said swelling agent comprises room temperature liquid polyols blended with monoanhydroalditols selected from the group consisting of styracitol, polyalitol, D-fructose, 1,4 anhydro-D-mannitol rand 1,4 anhydro-D-glucitol.

22. The adhesive composite of claim 1, wherein said swelling agent comprises room temperature liquid polyols blended with monosaccharides selected from the group consisting of pentoses, hexoses and heptoses.

23. The adhesive composite of claim 1, wherein said swelling agent comprises room temperature liquid polyols blended with ether alcohols selected from the group consisting of poly(ethylene) glycol ether and polypropylene glycol ether.