System and method for stent retention

• US 6,682,553 B1
• Filed: 12/28/2000
• Issued: 01/27/2004
• Est. Priority Date: 12/28/2000
• Status: Active Grant

• Current Assignee: Advanced Cardiovascular Systems Incorporated
• Original Assignee: Advanced Cardiovascular Systems Incorporated
• Inventors: Webler, William E. Jr.
• Primary Examiner(s): McDermott, Corrine
• Assistant Examiner(s): Phan, Hieu
• Application Number:
  US09/753,225
• Time in Patent Office: 1,125 Days
• Field of Search: 623/1.1, 623/1.11, 623/1.13, 623/1.23, 623/1-9-
• US Class Current: 623/1.11
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/9583 Means for holding the stent on the balloon, e.g. using protrusions, adhesives or an outer sleeve

Abstract

The system and method for retaining a stent on an expandable stent delivery member involves applying a plastic material that will adhere or fuse to the expandable stent delivery member, and that is insoluble in blood, to one or both of the expandable stent delivery member and the stent, and mounting the stent over the expandable stent delivery member. The plastic material may be dissolved in a solvent to form a dispersion, and applied to the expandable stent delivery member and/or the stent, and is allowed to evaporate to deposit the plastic material. The plastic material also may be applied after the stent is mounted on the expandable stent delivery member, as a coating, or may be applied as knobs or fillets onto the expandable stent delivery member through the openings of the stent. Alternatively, a plastic material may be melted, applied as knobs or fillets onto the expandable stent delivery member through the openings of the stent, and allowed to cool, to retain the stent on the expandable stent delivery member. A system is also provided for applying a melted plastic material on an expandable stent delivery member for retaining a stent on the expandable stent delivery member.

Claims

1. A method for retaining a stent on an expandable stent delivery member, the stent including a plurality of struts and openings defined in the surface of the stent between the struts, comprising the steps of:

applying a plastic material that is insoluble in blood to at least one of the expandable stent delivery member and the stent; and

mounting the stent over the expandable stent delivery member by disposing the stent on the expandable stent delivery member, and applying heat and pressure to the stent and the expandable stent delivery member to form ridges of plastic material in the openings of the stent adjacent to the struts, to retain the stent on the expandable stent delivery member.

2. The method of claim 1, wherein the plastic material is selected from the group consisting of plastics, organic materials, resins, two part resins, a UV cured plastic material, polymers, and copolymers, and combinations thereof.

3. The method of claim 1, wherein the plastic material is selected from the group consisting of ethylene acrylic acid, polyvinyl chloride, ethylene vinyl acetate copolymers, ethylene glycol butyl ether acetate copolymers, ethylene methyl acrylate copolymers, ethylene acrylic ester copolymers, ethylene acrylic ester-maleic anhydride terpolymers, and acid copolymer resins.

4. The method of claim 1, wherein the plastic material further comprises a therapeutic agent selected from the group consisting of compatible anti-thrombus agents and drugs for reducing the likelihood of clots forming on the stent and the stent delivery member during exposure of the stent and the stent delivery member to blood.

5. The method of claim 1, wherein the plastic material further comprises an anti-restenosis agent.

6. The method of claim 1, wherein the plastic material further comprises a cross-linking agent selected from the group consisting of cross-linking catalysts and resins.

7. The method of claim 1, wherein the plastic material will adhere to the expandable stent delivery member.

8. The method of claim 7, wherein the step of mounting the stent over the expandable stent delivery member creates an adhesive bond between the stent and the expandable stent delivery member.

9. The method of claim 1, wherein the step of applying the plastic material comprises dissolving the plastic material in a solvent to form a dispersion and applying the dispersion of the plastic material to the expandable stent delivery member, and further comprising the step of evaporating the solvent from the dispersion of the plastic material on the expandable stent delivery member to deposit the plastic material on the expandable stent delivery member.

10. The method of claim 9, further comprising the step of folding the expandable stent delivery member prior to applying the dispersion of the plastic material on the expandable stent delivery member.

11. The method of claim 1, wherein the step of dissolving the plastic material in a solvent to form a dispersion comprises adjusting the dilution of the dispersion to control the thickness of the coating.

12. The method of claim 11, wherein the thickness of the applied plastic material does not exceed the thickness of the stent.

13. The method of claim 9, wherein the step of dissolving the plastic material in a solvent to form a dispersion comprises adjusting the dilution of the dispersion to be sufficiently thin so as to not significantly interfere with subsequent inflation of the expandable stent delivery member and deployment of the stent.

14. The method of claim 1, wherein the step of applying the plastic material comprises dissolving the plastic material in a solvent to form a dispersion, folding the expandable stent delivery member, and applying the dispersion of the plastic material on the expandable stent delivery member prior to the step of mounting the stent to the expandable stent delivery member, to form a thin coating of the dispersion of the plastic material on the expandable stent delivery member.

15. The method of claim 1, wherein the step of applying the plastic material comprises dissolving the plastic material in a solvent to form a dispersion, mounting the stent on the expandable stent delivery member, and applying the dispersion of the plastic material on the expandable stent delivery member and the stent to form a thin coating of the dispersion of the plastic material on the expandable stent delivery member and the stent.

16. The method of claim 1, wherein the expandable stent delivery member is an inflatable balloon member.

17. The method of claim 1, wherein the step of applying the plastic material comprises applying the plastic material by plasma grafting of the plastic material on the expandable stent delivery member.

18. The method of claim 1, wherein the step of applying the plastic material comprises applying the plastic material by plasma polymerization and deposition of the plastic material on the expandable stent delivery member.