Surfactant-free cosmetic, dermatological and pharmaceutical compositions

• US 6,682,750 B2
• Filed: 02/28/2002
• Issued: 01/27/2004
• Est. Priority Date: 03/03/2001
• Status: Active Grant

• Current Assignee: Clariant Produkte AG (Clariant AG)
• Original Assignee: Clariant GmbH (Clariant AG)
• Inventors: Morschhäuser, Roman, Löffler, Matthias, Hornung, Michael
• Primary Examiner(s): Padmanabhan, Sreeni
• Assistant Examiner(s): JIANG, SHAOJIA A
• Application Number:
  US10/086,039
• Publication Number:
  US 20020176835A1
• Time in Patent Office: 698 Days
• Field of Search: 526/264, 424/401, 514/613
• US Class Current: 424/401
• CPC Class Codes: A61K 47/10 Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
• CPC Class Codes: A61K 47/12 Carboxylic acids; Salts or anhydrides thereof
• CPC Class Codes: A61K 47/24 containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
• CPC Class Codes: A61K 47/44 Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin synthetic glycerides, e.g. medium-chain triglycerides, A61K47/14
• CPC Class Codes: A61K 8/8182 Copolymers of vinyl-pyrrolidones. Compositions of derivatives of such polymers
• CPC Class Codes: A61K 9/0014 Skin, i.e. galenical aspects of topical compositions non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00
• CPC Class Codes: A61Q 17/04 Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin

Abstract

The invention relates to surfactant-free cosmetic, dermatological and pharmaceutical compositions, comprising at least one copolymer consisting essentially of

a1) 1 to 50% by weight of the repeat structural unit of the formula (1)

 where n is an integer from 2 to 9, or

a2) 1 to 50% by weight of a mixture of the repeat structural unit of the formula (1) and the repeat structural unit of the formula (2)

 where R, R¹ and R² may be identical or different and are hydrogen or a linear or branched alkyl or alkenyl group having in each case 1 to 30 carbon atoms and

b) 49.99 to 98.99% by weight of the repeat structural unit of the formula (3)

 in which R³ is hydrogen, methyl or ethyl, Z is (C₁-C₈)-alkylene, n is an integer from 2 to 9 and X is an ammonium, alkali metal or alkaline earth metal ion and

c) 0.01 to 8% by weight of crosslinking structures which originate from monomers having at least two olefinic double bonds.

Claims

1. A surfactant-free cosmetic composition which comprises:

I) at least one copolymer consisting essentially of

a1) 1 to 50% by weight of the copolymer of the repeat structural unit of the formula (1)

 

where n is an integer from 2 to 9, or

a2) 1 to 50% by weight of the copolymer of a mixture of the repeat structural unit of the formula (1) and the repeat structural unit of the formula (2)

 

where R, R¹ and R² may be identical or different and are hydrogen or a linear or branched alkyl or alkenyl group having in each case 1 to 30 carbon atoms and

b) 49.99 to 98.99% by weight of the copolymer of the repeat structural unit of the formula (3)

 

in which R³ is hydrogen, methyl or ethyl, Z is (C₁-C₈)-alkylene, and X is an ammonium, alkali metal or alkaline earth metal ion and

c) 0.01 to 8% by weight of crosslinking structures derived from the group consisting of allyl acrylate or methacrylate, trimethylolpropane triacrylate, trimethylolpropane trimethacrylate, dipropylene glycol diallyl ether, polyglycol diallyl ether, triethylene glycol divinyl ether, hydroquinone diallyl ether, tetraallyloxyethanes tetraethylene glycol diacrylate, triallylamine, trimethylolpropane diallyl ether, methylenebisacrylamide, divinylbenrene, and mixtures thereof

II) 2 to 95% by weight of an oily substance; and

III) water

wherein said surfactant-free cosmetic composition comprises a stable composition.

2. The surfactant-free cosmetic composition of claim 1, wherein the copolymer consists of 2 to 30% by weight of the structural units a1) or a2), 69.5 to 97.5% by weight of the structural unit b) and 0.01 to 5% by weight of the crosslinking structures c).

3. The surfactant-free cosmetic composition of claim 1, wherein the copolymer consists of 3 to 15% by weight of the structural units a1) or a2), 84.5 to 96.5% by weight of the structural unit b) and 0.2 to 3% by weight of the crosslinking structures c).

4. The surfactant-free cosmetic composition of claim 1, wherein the copolymer consists of the structural unit a2).

5. The surfactant-free cosmetic composition of claim 1, wherein the structural unit according to formula (1) is derived from N-vinylpyrrolldone.

6. The surfactant-free cosmetic composition of claim 1, wherein X in the structural unit b) is NH₄⁺.

7. The surfactant-free cosmetic composition of claim 1, wherein the crosslinking structures c) are derived from the group consisting of allyl acrylate, allyl methacrylate, trimethylolpropane triacrylate, trimethylolpropane trimethacrylate, and mixtures thereof.

8. The surfactant-free cosmetic composition of claim 1, which comprises 0.01 to 10% by weight of the copolymer, based on the weight of said composition.

9. The surfactant-free cosmetic composition of claim 1, which further comprises organic solvents, cationic polymers, silicone compounds, film formers, superfatting agents, moisturizing agents, biogenic active ingredients, glycerol, preservatives, pearlizing agents, dyes and fragrances, hydrotropic agents, opacifiers, thickeners, dispersants, collagen hydrolysates, polypeptides, egg yolk, lecithin, lanolin deodorizing agents, substances with a keratolytic and keratoplastic action, enzymes, carrier substances, antioxidants, UV light protection filters, pigments and metal oxides, agents with an antimicrobial action and/or acidic active ingredients.

10. The surfactant-free cosmetic composition of claim 1, which further comprises 5 to 70% by weight of organic solvents, based on the total weight of said composition.

11. The surfactant-free cosmetic composition of claim 1, which has a pH of from 2 to 12.

12. The surfactant-free cosmetic composition claim 1, which has a pH of less than 6.5.

13. The surfactant-free cosmetic composition of claim 1 which is an emulsion.

14. The surfactant-free cosmetic composition of claim 1 which is a cream selected from the group consisting of a night cream, care cream, nutrient cream, cleansing milk, skin milk, sunscreen lotion, skin protection cream, and a body lotion or ointment.

15. The surfactant-free cosmetic composition of claim 1, which is a dermatological composition.

16. The surfactant-free cosmetic composition of claim 1, which is a skin cosmetic composition.

17. The surfactant-free cosmetic composition of claim 1, which is a hair cosmetic composition.

18. The surfactant-free cosmetic composition of claim 1, which is a pharmaceutical composition.

19. The surfactant-free cosmetic composition of claim 1, which is a dermatological care composition.

20. The surfactant-free cosmetic composition of claim 1, wherein the oily substances are selected from the group consisting of silicone oils, phenylsilicones, silicone resins and gums, mineral oils, animal oil , vegetable oils, synthetic oils, linear and/or branched fatty alcohols and fatty acid esters, esters of linear (C₆-C₁₃)-fatty acids with linear (C₆-C₂₀)-fatty alcohols, esters of branch (C₈-C₁₃)-carboxylic acids with linear (C₆-C₂₀)-fatty alcohols, esters of linear (C₈-C₁₈)-fatty acids with branched alcohols, esters of linear and/or branched fatty acids with polyhydric alcohols and/or Guerbet alcohols, triglycerides based on (C₆-C₁₀)-fatty acids, esters, waxes optionally in combination with hydrophilic waxes, fluorinated and perfluorinated oils;

fluorinated silicone oils, and mixtures thereof.