Method of protecting teeth against erosion

• US 6,685,920 B2
• Filed: 12/13/2002
• Issued: 02/03/2004
• Est. Priority Date: 11/12/1999
• Status: Expired due to Term

• Current Assignee: The Procter & Gamble Company
• Original Assignee: The Procter & Gamble Company
• Inventors: White, Donald J. Jr., Baig, Arif A., Faller, Robert V.
• Primary Examiner(s): Rose, Shep K.
• Application Number:
  US10/319,108
• Publication Number:
  US 20030165442A1
• Time in Patent Office: 417 Days
• Field of Search: 424/49-88
• US Class Current: 424/49
• CPC Class Codes: A23G 4/06 characterised by the composition containing organic or inorganic compounds
• CPC Class Codes: A23G 4/08 of the chewing gum base
• CPC Class Codes: A23G 4/126 containing vitamins, antibiotics
• CPC Class Codes: A61K 2800/52 Stabilizers
• CPC Class Codes: A61K 6/20 Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish
• CPC Class Codes: A61K 8/19 containing inorganic ingredients
• CPC Class Codes: A61K 8/21 Fluorides; Derivatives thereof
• CPC Class Codes: A61K 8/24 Phosphorous; Compounds thereof
• CPC Class Codes: A61K 8/81 obtained by reactions involving only carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61K 8/8147 Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
• CPC Class Codes: A61P 1/02 Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
• CPC Class Codes: A61Q 11/00 Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
• CPC Class Codes: C08L 1/00 Compositions of cellulose, modified cellulose or cellulose derivatives
• CPC Class Codes: C08L 25/18 Homopolymers or copolymers of aromatic monomers containing elements other than carbon and hydrogen
• CPC Class Codes: C08L 29/04 Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
• CPC Class Codes: C08L 3/00 Compositions of starch, amylose or amylopectin or of their derivatives or degradation products
• CPC Class Codes: C08L 31/04 Homopolymers or copolymers of vinyl acetate
• CPC Class Codes: C08L 33/06 of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical
• CPC Class Codes: C08L 71/02 Polyalkylene oxides

Abstract

Disclosed are methods of treating and protecting teeth against erosion by use of oral compositions comprising polymeric mineral surface active agents, metal ions such as stannous and zinc and combinations thereof. The present methods provide improved resistance of teeth to erosive demineralization or dissolution and prevention of tooth damage by subsequent exposure of teeth to erosive chemicals such as acidic foods and beverages.

Claims

1. A method of protecting a subject'"'"'s teeth from erosion caused by the action of chemicals including harsh abrasives and acids, said method comprising administering to the subject'"'"'s oral cavity an oral care composition comprising a polymeric mineral surface-active agent selected from condensed phosphorylated polymers, wherein said polymeric mineral surface-active agent is substantive to teeth and deposits a layer that protects teeth from erosive damage immediately after use of the oral composition and for a period of at least about one hour or longer thereafter and wherein said oral care composition is not intentionally swallowed for purposes of systemic administration but is rather retained in the oral cavity for a time sufficient to contact substantially all of the dental surfaces to deposit said protective layer.

2. A method according to claim 1, wherein wherein the polymeric mineral surface active agent comprised in the oral care composition is a linear polyphosphate having about four or more phosphate groups.

3. A method according to claim 2, wherein the oral care composition has a pH greater than about 5.5 to about 10.0.

4. A method according to claim 1, wherein the oral care composition administered to the subject, further comprises an effective amount of a source of metal ions selected from the group consisting of stannous, zinc, copper, and mixtures thereof.

5. A method according to claim 4, wherein the oral care composition comprises from about 500 ppm to about 20,000 ppm metal ions selected from stannous, zinc, copper, and mixtures thereof in the total composition.

6. A method of protecting a subject'"'"'s teeth from erosion comprising administering to the subject'"'"'s oral cavity an oral care composition having a pH of from greater than about 4.0 to about 10.0 and comprising a source of metal ions selected from the group consisting of stannous, zinc, copper, and mixtures thereof, wherein said metal ions form insoluble compounds or complexes that deposit on the tooth surface, thereby forming a film or coating that protects teeth from erosive damage immediately after use of the oral composition and for at least about one hour thereafter, and wherein the composition is essentially free of ethylenediaminetetracetates and phytates.

7. A method according to claim 6, wherein the oral care composition comprises from about 500 ppm to about 20,000 ppm the metal ions.