Diphasic injection composition containing dispersed and continuous phases useful for reparative and plastic surgery
First Claim
1. A biocompatible diphasic composition comprising a dispersed phase and a continuous phase, said dispersed phase residing in suspension in said continuous phase, wherein said dispersed phase consists of particles of at least one hydrogel of a polymer/copolymer obtained by polymerizing and cross-linking acrylic acid, methacrylic acid and/or at least one derivative of said acids;
- and wherein said continuous phase is an aqueous solution or hydrogel of at least one polymer selected from proteins, polysaccharides and their derivatives, which has been cross-linked.
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Abstract
Biocompatible diphasic compositions are prepared comprising a dispersed phase suspended in a continuous phase, more particularly suitable for use as a filling material in reparative and plastic surgery. The dispersed phase consists of particles of at least one hydrogel of a (co)polymer obtained by polymerizing and cross-linking acrylic acid, methacrylic acid and/or at least one derivative of said acids. The continuous phase is an aqueous solution or hydrogel of a polymer selected from proteins, polysaccharides and their derivatives which have been cross-linked. The polysaccharide may be hyaluronic acid, its salts and a mixture of its salts, advantageously consisting of a sodium hyaluronate.
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Citations
24 Claims
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1. A biocompatible diphasic composition comprising a dispersed phase and a continuous phase, said dispersed phase residing in suspension in said continuous phase, wherein said dispersed phase consists of particles of at least one hydrogel of a polymer/copolymer obtained by polymerizing and cross-linking acrylic acid, methacrylic acid and/or at least one derivative of said acids;
- and wherein said continuous phase is an aqueous solution or hydrogel of at least one polymer selected from proteins, polysaccharides and their derivatives, which has been cross-linked.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
Specification