Methods and apparatus for determining instantaneous elastic recoil and assistance pressure during ventilatory support
First Claim
1. A method for determining an instantaneous elastic recoil pressure comprising the steps of:
- specifying an elastance for a subject;
providing the subject with ventilatory support;
determining a measure of respiratory airflow;
determining an index value representing an extent to which a leak is suddenly changing using said measure of respiratory airflow;
calculating an inspired volume of airflow as a function of said measure of respiratory airflow and said index value and;
calculating said instantaneous elastic recoil pressure as a function of said inspired volume and said elastance.
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Accused Products
Abstract
The apparatus provides for the determination of the instantaneous phase in the respiratory cycle, subject'"'"'s average respiration rate and the provision of ventilatory assistance. A microprocessor (16) receives an airflow signal from a pressure transducer (18) coupled to a port (17) at a mask (11). The microprocessor (16) controls a servo (19), that in turn controls the fan motor (20) and thus the pressure of air delivered by the blower (10). The blower (10) is coupled to a subject'"'"'s mask (ii) by a conduit (12). The invention seeks to address the following goals: while the subject is awake and making substantial efforts the delivered assistance should be closely matched in phase with the subject'"'"'s efforts; the machine should automatically adjust the degree of assistance to maintain at least a specified minimum ventilation without relying on the integrity of the subject'"'"'s chemoreflexes; and it should continue to work correctly in the pesence of large leaks.
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Citations
64 Claims
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1. A method for determining an instantaneous elastic recoil pressure comprising the steps of:
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specifying an elastance for a subject;
providing the subject with ventilatory support;
determining a measure of respiratory airflow;
determining an index value representing an extent to which a leak is suddenly changing using said measure of respiratory airflow;
calculating an inspired volume of airflow as a function of said measure of respiratory airflow and said index value and;
calculating said instantaneous elastic recoil pressure as a function of said inspired volume and said elastance. - View Dependent Claims (2, 3, 4)
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5. An apparatus for determining an instantaneous elastic recoil pressure during the provision of respiratory assistance comprising:
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an air supply means controllable to supply breathable air to a subject'"'"'s airway continually at a selectable pressure elevated above atmospheric pressure as a function of an instantaneous elastic pressure;
a flow sensor means to generate a flow signal representative of respiratory airflow; and
a processor means to process a flow signal from said flow sensor and to control said air supply means, wherein said processor is programmed to;
receive as input an elastance value for a subject;
calculate an index value representing an extent to which any leak is suddenly changing using sampled flow values from said flow signal;
calculating an inspired volume of airflow as a function of said measure of respiratory airflow and said index value; and
calculating said instantaneous elastic recoil pressure as a function of said inspired volume and said elastance value. - View Dependent Claims (6, 7)
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8. An apparatus for determining an instantaneous elastic recoil pressure during the provision of respiratory assistance comprising:
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a blower and mask to supply breathable air to a subject'"'"'s airway continually at a selectable pressure elevated above atmospheric pressure as a function of an instantaneous elastic pressure;
a pressure transducer to generate a flow signal representative of respiratory airflow; and
a processor to process a flow signal from said pressure transducer and to control said blower, wherein said processor is programmed to;
receive as input an elastance value for a subject;
calculate an index value representing an extent to which any leak is suddenly changing using sampled flow values from said flow signal;
calculating an inspired volume of airflow as a function of said measure of respiratory airflow and said index value; and
calculating said instantaneous elastic recoil pressure as a function of said inspired volume and said elastance value. - View Dependent Claims (9, 10)
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11. A method for determining an instantaneous elastic recoil pressure comprising the steps of:
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specifying an elastance for a subject;
specifying a ventilation target;
providing the subject with respiratory support;
calculating a phase index representing a phase in the subject'"'"'s respiration;
calculating said instantaneous elastic recoil pressure as a function of (a) said elastance, (b) said ventilation target, and (c) a function of said phase index. - View Dependent Claims (12, 13, 14)
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15. An apparatus for determining an instantaneous elastic recoil pressure during the provision of respiratory assistance comprising:
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an air supply means controllable to supply breathable air to a subject'"'"'s airway continually at a selectable pressure elevated above atmospheric pressure as a function of an instantaneous elastic recoil pressure;
a flow sensor means to generate a flow signal representative of respiratory airflow; and
a processor means to process a flow signal from said flow sensor and to control said air supply means, wherein said processor is programmed to;
accept an elastance value for a subject;
accept a ventilation target;
calculate a phase index representing the instantaneous phase in the subject'"'"'s respiration;
calculate said instantaneous elastic recoil pressure as a function of (a) said elastance, (b) said ventilation target, and (c) a function of said phase index. - View Dependent Claims (16, 17)
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18. An apparatus for determining an instantaneous elastic recoil pressure during the provision of respiratory assistance comprising:
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a blower and mask to supply breathable air to a subject'"'"'s airway continually at a selectable pressure elevated above atmospheric pressure as a function of an instantaneous elastic recoil pressure;
a pressure transducer to generate a flow signal representative of respiratory airflow; and
a processor to process a flow signal from said pressure transducer and to control said blower, wherein said processor is programmed to;
accept an elastance value for a subject;
accept a ventilation target;
calculate a phase index representing the instantaneous phase in the subject'"'"'s respiration;
calculate said instantaneous elastic recoil pressure as a function of (a) said elastance, (b) said ventilation target, and (c) a function of said phase index. - View Dependent Claims (19, 20)
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21. A method for determining an instantaneous elastic recoil pressure comprising the steps of:
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specifying an elastance for a subject;
specifying a ventilation target;
providing the subject with respiratory support;
calculating a phase index representing a phase in the subject'"'"'s respiration from said flow signal;
calculating the subject'"'"'s respiratory rate; and
calculating said instantaneous elastic recoil pressure as a function of (a) the elastance, (b) the ventilation target, (c) the respiratory rate, and (d) a function of the phase index. - View Dependent Claims (22, 23, 24)
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25. An apparatus for determining an instantaneous elastic recoil pressure during the provision of respiratory assistance comprising:
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an air supply means controllable to supply breathable air to a subject'"'"'s airway continually at a selectable pressure elevated above atmospheric pressure as a function of an instantaneous elastic recoil pressure;
a flow sensor means to generate a flow signal representative of respiratory airflow; and
a processor means to process a flow signal from said flow sensor and to control said air supply means, wherein said processor is programmed to;
accept an elastance value for a subject;
accept a ventilation target;
calculate a phase index representing a phase in the subject'"'"'s respiration using flow values sampled from said flow signal;
calculate the subject'"'"'s respiratory rate; and
calculate said instantaneous elastic recoil pressure as a function of (a) the elastance, (b) the ventilation target, (c) the respiratory rate, and (d) a function of the phase index. - View Dependent Claims (26, 27)
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28. An apparatus for determining an instantaneous elastic recoil pressure during the provision of respiratory assistance comprising:
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a blower and mask to supply breathable air to a subject'"'"'s airway continually at a selectable pressure elevated above atmospheric pressure as a function of an instantaneous elastic recoil pressure;
a pressure transducer to generate a flow signal representative of respiratory airflow; and
a processor to process a flow signal from said pressure transducer and to control said blower, wherein said processor is programmed to;
accept an elastance value for a subject;
accept a ventilation target;
calculate a phase index representing a phase in the subject'"'"'s respiration using flow values sampled from said flow signal;
calculate the subject'"'"'s respiratory rate; and
calculate said instantaneous elastic recoil pressure as a function of (a) the elastance, (b) the ventilation target, (c) the respiratory rate, and (d) a function of the phase index. - View Dependent Claims (29, 30)
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31. A method for determining an instantaneous elastic recoil pressure comprising the steps of:
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providing the subject with respiratory support;
calculating a phase index representing an instantaneous phase in the subject'"'"'s respiration;
determining instantaneous elastic assistance pressure;
low pass filtering said instantaneous elastic assistance pressure; and
calculating said instantaneous elastic recoil pressure from a function of the low pass filtered instantaneous elastic assistance pressure and a function of the phase index. - View Dependent Claims (32)
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33. An apparatus for determining an instantaneous elastic recoil pressure during the provision of respiratory assistance comprising:
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an air supply means controllable to supply breathable air to a subject'"'"'s airway continually at a selectable pressure elevated above atmospheric pressure as a function of an instantaneous elastic pressure;
a flow sensor means to generate a flow signal representative of respiratory airflow; and
a processor means to process a flow signal from said flow sensor and to control said air supply means, wherein said processor is programmed to;
calculate a phase index representing a phase in the subject'"'"'s respiration using flow values sampled from said flow signal;
calculate an instantaneous elastic assistance pressure;
low pass filter said instantaneous elastic assistance pressure; and
calculate said instantaneous elastic recoil pressure from a function of the low pass filtered instantaneous elastic assistance pressure and a function of the phase index. - View Dependent Claims (34)
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35. An apparatus for determining an instantaneous elastic recoil pressure during the provision of respiratory assistance comprising:
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a blower and mask controllable to supply breathable air to a subject'"'"'s airway continually at a selectable pressure elevated above atmospheric pressure as a function of an instantaneous elastic pressure;
a pressure transducer to generate a flow signal representative of respiratory airflow; and
a processor to process a flow signal from said pressure transducer and to control said blower, wherein said processor is programmed to;
calculate a phase index representing a phase in the subject'"'"'s respiration using flow values sampled from said flow signal;
calculate an instantaneous elastic assistance pressure;
low pass filter said instantaneous elastic assistance pressure; and
calculate said instantaneous elastic recoil pressure from a function of the low pass filtered instantaneous elastic assistance pressure and a function of the phase index. - View Dependent Claims (36)
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37. A method for determining an instantaneous elastic assistance pressure during the provision of respiratory support comprising the steps of:
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specifying an elastance for a subject;
providing the subject with ventilatory support;
calculating two or more estimated values for instantaneous elastic recoil pressure as a function of said elastance;
calculating a weighted average recoil pressure from a weighted average of said estimated values; and
determining an instantaneous elastic assistance pressure as a function of the weighted average recoil pressure. - View Dependent Claims (38, 39, 40, 41, 42, 43, 44, 45, 46)
determining a measure of respiratory airflow;
determining an index value representing an extent to which any leak is suddenly changing using said measure of respiratory airflow;
calculating an inspired volume of airflow as an integral of a function of said index value and said measure of respiratory airflow; and
calculating an estimated value of elastic recoil pressure as a function of said inspired volume and said elastance.
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44. The method of claim 43 wherein one of said estimated values of elastic recoil pressure is derived by the steps of:
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determining a target tidal volume;
calculating a phase index representing a phase in the subject'"'"'s respiration; and
calculating an estimated value of elastic recoil pressure as a function of (a) said elastance, (b) said target tidal volume, and (c) a function of the phase index.
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45. The method of claim 44 wherein one of said estimated values of elastic recoil pressure is derived by the steps of:
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specifying a target ventilation;
calculating the subject'"'"'s respiratory rate; and
calculating an estimated value of elastic recoil pressure from a function of (a) the elastance, (b) the target ventilation, (c) the respiratory rate, and (d) a function of the phase index.
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46. The method of claim 45 wherein one of said estimated values of elastic recoil pressure is derived by the steps of:
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low pass filtering a previously determined instantaneous elastic assistance; and
calculating an estimated value of elastic recoil pressure from a function of the low pass filtered instantaneous elastic assistance and a function of the phase index.
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47. An apparatus for determining an instantaneous elastic assistance pressure during the provision of respiratory assistance comprising:
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an air supply means controllable to supply breathable air to a patient'"'"'s airway continually at a selectable pressure elevated above atmospheric pressure as a function of an instantaneous elastic assistance pressure value;
a flow sensor means to generate a flow signal representative of respiratory airflow; and
a processor means to process a flow signal from said flow sensor and to control said air supply means, wherein said processor is programmed to;
receive as input an elastance value for a patient;
calculate two or more estimated elastic recoil pressure values as a function of said elastance value;
calculate a weighted average recoil pressure value from a weighted average of said estimated values; and
determine the instantaneous elastic assistance pressure value as a function of the weighted average recoil pressure value. - View Dependent Claims (48, 49, 50, 51, 52, 53, 54, 55)
determining an index value representing an extent to which any leak is suddenly changing using flow values sampled from said flow signal;
calculating an inspired volume of airflow as an integral of a function of said index value and said flow values; and
calculating an estimated value of elastic recoil pressure as a function of said inspired volume and said elastance value.
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53. The apparatus of claim 52 wherein one of said estimated values of elastic recoil pressure is calculated by said processor through the steps of:
- processing a target tidal volume value;
calculating a phase index representing a phase in the subject'"'"'s respiration using said flow values; and
calculating an estimated value of elastic recoil pressure as a function of (a) said elastance value, (b) said target tidal volume value, and (c) a function of the phase index.
- processing a target tidal volume value;
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54. The apparatus of claim 53 wherein one of said estimated values of elastic recoil pressure is calculated by said processor through the steps of:
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processing a target ventilation value;
calculating the subject'"'"'s respiratory rate; and
calculating an estimated value of elastic recoil pressure from a function of (a) the elastance value, (b) the target ventilation value, (c) the respiratory rate, and (d) a function of the phase index.
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55. The apparatus of claim 54 wherein one of said estimated values of elastic recoil pressure is calculated by said processor through the steps of:
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low pass filtering a previously determined instantaneous elastic assistance pressure value; and
calculating an estimated value of elastic recoil pressure from a function of the low pass filtered instantaneous elastic assistance value and a function of the phase index.
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56. An apparatus for determining an instantaneous elastic assistance pressure during the provision of respiratory assistance comprising:
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a blower and mask controllable to supply breathable air to a patient'"'"'s airway continually at a selectable pressure elevated above atmospheric pressure as a function of an instantaneous elastic assistance pressure value;
a pressure transducer to generate a flow signal representative of respiratory airflow; and
a processor to process a flow signal from said pressure transducer and to control said blower, wherein said processor is programmed to;
receive as input an elastance value for a patient;
calculate two or more estimated elastic recoil pressure values as a function of said elastance value;
calculate a weighted average recoil pressure value from a weighted average of said estimated values; and
determine the instantaneous elastic assistance pressure value as a function of the weighted average recoil pressure value. - View Dependent Claims (57, 58, 59, 60, 61, 62, 63, 64)
determining an index value representing an extent to which any leak is suddenly changing using flow values sampled from said flow signal;
calculating an inspired volume of airflow as an integral of a function of said index value and said flow values; and
calculating an estimated value of elastic recoil pressure as a function of said inspired volume and said elastance value.
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62. The apparatus of claim 61 wherein one of said estimated values of elastic recoil pressure is calculated by said processor through the steps of:
- processing a target tidal volume value;
calculating a phase index representing a phase in the subject'"'"'s respiration using said flow values; and
calculating an estimated value of elastic recoil pressure as a function of (a) said elastance value, (b) said target tidal volume value, and (c) a function of the phase index.
- processing a target tidal volume value;
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63. The apparatus of claim 62 wherein one of said estimated values of elastic recoil pressure is calculated by said processor through the steps of:
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processing a target ventilation value;
calculating the subject'"'"'s respiratory rate; and
calculating an estimated value of elastic recoil pressure from a function of (a) the elastance value, (b) the target ventilation value, (c) the respiratory rate, and (d) a function of the phase index.
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64. The apparatus of claim 63 wherein one of said estimated values of elastic recoil pressure is calculated by said processor through the steps of:
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low pass filtering a previously determined instantaneous elastic assistance pressure value; and
calculating an estimated value of elastic recoil pressure from a function of the low pass filtered instantaneous elastic assistance value and a function of the phase index.
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Specification