Method and apparatus for treating adult-onset dementia of the Alzheimer's type

• US 6,689,085 B1
• Filed: 09/05/2000
• Issued: 02/10/2004
• Est. Priority Date: 07/11/1996
• Status: Expired due to Fees

• Current Assignee: Integra Lifesciences Corporation (Integra LifeSciences Holdings Corporation)
• Original Assignee: Eunoe, Inc. (Integra LifeSciences Holdings Corporation)
• Inventors: Rubenstein, Edward, Vargas, Jaime S., Saul, Tom A., Levinthal, Elliott C., Karshmer, David L.
• Primary Examiner(s): Casler, Brian L.
• Assistant Examiner(s): Thissell, Jeremy
• Application Number:
  US09/654,967
• Time in Patent Office: 1,253 Days
• Field of Search: 604/8-10
• US Class Current: 604/9
• CPC Class Codes: A61M 27/006 Cerebrospinal drainage; Accessories therefor, e.g. valves
• CPC Class Codes: A61M 60/882 Devices powered by the patient, e.g. skeletal muscle powered devices

Abstract

A method for treating a patient for adult-onset dementia of the Alzheimer'"'"'s type by removing a portion of the patient'"'"'s cerebrospinal fluid, preferably (although not necessarily) by transporting the fluid to another portion of the patient'"'"'s body. The invention also provides an apparatus for removing cerebrospinal fluid including (1) a conduit with a first opening and a second opening, the first opening of the conduit being adapted to be disposed in fluid communication with a space within a patient'"'"'s subarachnoid space, the second opening being adapted to be disposed in fluid communication with another portion of the patient'"'"'s body; and (2) a flow rate control device attached to the conduit.

Claims

1. An apparatus for removing cerebrospinal fluid comprising:

a conduit comprising a first opening and a second opening, the first opening of the conduit being adapted to be disposed in fluid communication with a space within a patient'"'"'s subarachnoid space the second opening being adapted to be disposed in fluid communication with another portion of the patient'"'"'s body; and

a pump attached to the conduit between the first and second openings;

said pump being adapted for coupling to structure within the patient'"'"'s body so that the pumping is effected by motion of the structure or changes in internal body pressure as the patient moves.

2. The apparatus of claim 1, wherein the pump has an outlet and the conduit is a first conduit, the second opening of the first conduit being in fluid communication with the pump outlet, the apparatus further comprising a second conduit having a first opening in fluid communication with the pump outlet and a second opening adapted for being placed in communication with space within the patient'"'"'s subarachnoid space.

3. The apparatus of claim 2, wherein the device further comprises a valve for controlling flow from the pump outlet to the second conduit.

4. The apparatus of claim 1, wherein the pump comprises a bellows adapted for coupling to the structure within the patient'"'"'s body.

5. The apparatus of claim 4, wherein the bellows is adapted to be powered by motion of the patient'"'"'s diaphragm.

6. The apparatus of claim 1, wherein the pump is a piston pump and includes a piston slidably mounted therein.

7. The apparatus of claim 6, wherein the piston is adapted to be powered by changes in pressure in the patient'"'"'s thoracic cavity.

8. The apparatus of claim 7, wherein the piston has a surface that is exposed to the environment external to the pump.

9. The apparatus of claim 1, wherein the pump is a diaphragm pump.

10. The apparatus of claim 9, wherein the pump has a diaphragm that forms an outer surface of the pump and is exposed to an internal body pressure environment external to the pump.

11. The apparatus of claim 9, wherein the diaphragm is adapted to be powered by pressure changes in the patient'"'"'s thoracic cavity.

12. The apparatus of claim 1, further comprising a relief valve coupled to the conduit in the vicinity of the first opening.