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Method of using a catheter for delivery of ultrasonic energy and medicament

  • US 6,689,086 B1
  • Filed: 07/29/1999
  • Issued: 02/10/2004
  • Est. Priority Date: 10/27/1994
  • Status: Expired due to Term
First Claim
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1. A method for ultrasonic ablation of matter from an anatomical passageway of a mammalian body and for concomitant delivery of a liquid medicament, said method comprising the steps of:

  • inserting into the mammalian body distal end first an ultrasound delivery/medicament infusion catheter comprising an elongate flexible catheter body having a longitudinal axis, a proximal end and a distal end, a distal tip member attached to the distal end of the catheter body, an ultrasound transmission member extending longitudinally through said catheter body and attached at the distal end thereof to the distal tip member for transmitting ultrasound energy to the distal tip member, a medicament infusion lumen extending longitudinally through said catheter body and opening through at least one medicament outlet aperture formed in the distal tip member and oriented radially outward in relation to the longitudinal axis of said catheter body;

    advancing the distal end of said catheter to a desired operative position relative to the obstruction to be ablated;

    generating ultrasonic energy at a location outside the catheter body;

    coupling said generated ultrasonic energy to the ultrasound transmission member at the proximal end of the catheter body;

    passing ultrasonic energy through said ultrasound transmission member to the distal tip member at the distal end of said catheter such that the distal end of said catheter will undergo ultrasonic vibration at a frequency which will result in ablation of said obstruction; and

    passing a flow of medicament through said medicament infusion lumen and out of said radially-oriented medicament outlet aperture formed in the distal tip member concurrently with the delivery of said ultrasonic energy through said catheter.

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