Microdevice and method of delivering or withdrawing a substance through the skin of an animal
DC CAFCFirst Claim
1. A device for intradermally delivering or withdrawing a substance through at least one layer of the skin of a patient, said device comprising:
- a body having a bottom face, a top face spaced from said bottom face, a side edge, and a width, said body having a height extending between said top face and said bottom face that is less than said width, said body defining a channel extending longitudinally from said edge, substantially parallel to said bottom face;
a skin penetrating device coupled to said bottom face and being in fluid communication with said channel, said skin penetrating device comprises a base and a plurality of skin penetrating members arranged in an array and extending outwardly from said base; and
wherein said body defines a recess in said bottom face, said recess being dimensioned to receive said skin penetrating device, said skin penetrating device being mounted in said recess, and wherein said channel is in fluid communication with said recess for supplying the substance to said skin penetrating device.
2 Assignments
Litigations
0 Petitions
Accused Products
Abstract
A device for withdrawing or delivering a substance through the skin of a patient includes a body and a skin penetrating device having a plurality of skin penetrating members, such microneedles. The body includes a bottom surface having a first inner surface area supporting the skin penetrating members and a second outer surface having an adhesive for attaching the device to the skin. In one embodiment, the firs inner surface is spaced outwardly from the second outer surface when the device is attached to the skin. The inner surface can have a textured visually wettable surface, such as an etched surface, to provide a visual indication of leakage from the interface between the skin penetrating members and the skin.
-
Citations
39 Claims
-
1. A device for intradermally delivering or withdrawing a substance through at least one layer of the skin of a patient, said device comprising:
-
a body having a bottom face, a top face spaced from said bottom face, a side edge, and a width, said body having a height extending between said top face and said bottom face that is less than said width, said body defining a channel extending longitudinally from said edge, substantially parallel to said bottom face;
a skin penetrating device coupled to said bottom face and being in fluid communication with said channel, said skin penetrating device comprises a base and a plurality of skin penetrating members arranged in an array and extending outwardly from said base; and
wherein said body defines a recess in said bottom face, said recess being dimensioned to receive said skin penetrating device, said skin penetrating device being mounted in said recess, and wherein said channel is in fluid communication with said recess for supplying the substance to said skin penetrating device. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
-
-
11. A device for intradermally delivering or withdrawing a substance through at least one layer of the skin of a patient, said device comprising:
-
a body having a top face and a bottom face, said bottom face having a first surface area lying in a first plane and a second surface area lying in a second plane, said first surface area being spaced outwardly from said second surface area; and
a skin penetrating device extending from said first surface area of said bottom face and being oriented to penetrate the surface of said skin of said patient; and
wherein said bottom face includes a leak detector for indicating leakage of said substance from between said skin penetrating device and said skin of said patient. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
-
-
20. A device for intradermally delivering or withdrawing a substance through at least one layer of the skin of a patient, said device comprising:
-
a body having a top face and a bottom face; and
at least one skin penetrating member coupled to said body and extending outwardly from said bottom face;
said bottom face having a first surface area surrounding said at least one skin penetrating member, said first surface area having a leak detector for indicating the presence of a substance in contact with said bottom face. - View Dependent Claims (21, 22, 23, 24, 25)
-
-
26. A method of delivering or withdrawing a substance through at least one layer of the skin of a patient, said method comprising the steps of:
-
providing a device having a body with a bottom face, at least one skin penetrating device arranged on said bottom face, said bottom face including a first surface area arranged in a first plane and surrounding said skin penetrating device and a second surface area arranged in a second plane, said first surface area being spaced outwardly from said second surface area and having a leak detector;
positioning said skin penetrating device on a target site of said skin of said patient;
applying a pressure against said device sufficient for said skin penetrating device to penetrate said skin and for said second surface area to contact said skin; and
delivering a substance to or withdrawing a substance from said target site of said patient. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34)
-
-
35. A microdevice interface, comprising:
-
a body having a top face and a bottom face, said bottom face having a first surface area and a second surface area, said first surface area being raised from said body with respect to said second surface area;
a recess defined in said first surface area said recess having a height that is less than a width;
an opening defined in said body for fluid flow into and out of said body, said opening being in fluid communication with said recess;
wherein said opening and said recess are in fluid communication via a second opening, said second opening being perpendicular to a plane of the device. - View Dependent Claims (36, 37, 38, 39)
-
Specification