Device for measuring a volume of drug

• US 6,689,108 B2
• Filed: 03/20/2001
• Issued: 02/10/2004
• Est. Priority Date: 11/13/1998
• Status: Expired due to Fees

• Current Assignee: Elan Pharma International Limited (Perrigo Company PLC)
• Original Assignee: Elan Pharma International Limited (Perrigo Company PLC)
• Inventors: Tsals, Izrail, Lavi, Gilad, Yigal, Gil
• Primary Examiner(s): Mendez, Manuel
• Assistant Examiner(s): Han, Mark K.
• Application Number:
  US09/812,990
• Publication Number:
  US 20020007671A1
• Time in Patent Office: 1,057 Days
• Field of Search: 604/110, 604/131, 604/138, 604/139, 604/156, 604/181, 604/183, 604/186, 604/187, 604/191, 604/192, 604/194, 604/195, 604/196, 604/197, 604/199, 604/200, 604/205, 604/207, 604/211, 604/224, 604/232, 604/246, 604/264, 604/272, 604/518
• US Class Current: 604/211
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 5/1782 Devices aiding filling of syringes in situ combination of a vial and a syringe for transferring or mixing their contents A61J1/2096, filling of medical containers in general B65B3/003
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/2046 Media being expelled from injector by gas generation, e.g. explosive charge
• CPC Class Codes: A61M 5/2053 Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/2425 by compression of deformable ampoule or carpule wall
• CPC Class Codes: A61M 5/2448 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/3234 Fully automatic needle retraction, i.e. in which triggering of the needle does not require a deliberate action by the user

Abstract

A device for measuring a volume of liquid drug. The device includes a first chamber containing liquid drug, a measurement chamber in liquid communication with the first chamber, and a measurement assembly.

Claims

1. A device for measuring and delivering a desired volume of liquid drug, said device comprising:

a housing including;

a first chamber containing liquid drug;

a measurement chamber in liquid communication with the first chamber;

a measurement assembly for establishing a desired amount of liquid drug, said measurement assembly comprising;

a piston, slidably received in the measurement chamber;

a member in radial transmission relation to the piston; and

a knob in radial transmission relation to the member whereby movement of the knob moves the piston along the measurement chamber which causes aspiration of the liquid drug into the measurement chamber; and

parenteral delivery means for delivering said desired amount of liquid drug to a living being.

2. The device of claim 1 wherein the piston comprises a piston head and a threaded rod.

3.The device of claim 2 wherein the piston head is made of rubber.

3. The device of claim 1 wherein the member has axial internal threads along a portion of its length.

4. The device of claim 1 wherein the measurement assembly further comprises:

a sleeve slidably received within the measurement chamber along a portion of the length of the chamber, and for slidably receiving the member, the sleeve having a annular recess;

and a spring mounted axially within the sleeve.

7. The device of claim 1 wherein said parenteral delivery means comprises a needle in fluid communication with said measurement chamber, said needle being movable out of said housing defining a first position and into the skin of a living being, defining a second position, for delivering said measured drug volume therein.

5. The device of claim 5 wherein the member further comprises an annular extension along a portion of the outer surface of the member to matingly engage the annular recess when said knob is pressed.

6. The device of claim 6 wherein one end of the sleeve abuts the measurement chamber wall and the other end of the sleeve abuts the knob.

8. The device of claim 8 wherein said parenteral delivery means further comprises means for automatically returning said needle to said first position from said second position when drug delivery is completed.

9. The device of claim 9 wherein said parenteral delivery means further comprises means for preventing said needle from being moved to said second position after said needle has been automatically returned to said first position.

10. A device for delivering a measured volume of drug comprising:

a first chamber containing liquid drug;

a measurement chamber in liquid communication with the first chamber;

a measurement assembly comprising a piston being frictionally received into the measurement chamber, a member in radial transmission relation to the piston, the member having an annular extension, and a knob in radial transmission relation to the member and slidably and resiliently mounted to the measurement chamber;

an axial spring providing axial force to the piston and the knob;

a sleeve slidably mounted within a portion of the length of the measurement chamber, the sleeve having a radial recess for mating receipt of the annular extension of the member; and

a needle in liquid communication with the measurement chamber, whereby when the knob is rotated, it causes the member to engage in radial transmission with the piston causing the piston to move axially along the length of measurement chamber thereby causing drug solution to aspirate into the measurement chamber, and then when the knob is depressed inwardly relative to the measurement chamber it causes the annular extension to be received into the radial recess in the sleeve, thereby releasing the radial transmission relation between the member and the piston, causing axial extension of the spring against the piston and flow of liquid drug from the measurement chamber and through the needle.

11. The device of claim 11 wherein the piston comprises a piston head and a threaded rod.

13. The device of claim 11 where the member has axial internal threads along a portion of its length.

14. The device in claim 11 wherein one end of the sleeve abuts the measurement chamber wall and the other end of the sleeve abuts the knob.

12. The device of claim 12 wherein the piston head is made of rubber.

15. A method of measuring a volume of liquid drug comprising the steps of:

providing a first chamber containing liquid drug;

providing a measurement chamber in liquid communication with the first chamber;

providing a measurement assembly comprising a piston, slidably received in the measurement chamber, a member in radial transmission relation to the piston, and a knob in radial transmission relation to the member and slidably mounted axially to the measurement chamber; and

rotating the knob to a desired setting thereby causing liquid drug to aspirate from the first chamber into the measurement chamber to reach a measured volume.

16. A method of delivering a measured volume of liquid drug comprising the steps of:

providing a first chamber containing liquid drug;

providing a measurement chamber in liquid communication with the first chamber;

providing a measurement assembly comprising a piston, slidably received in the measurement chamber, a member in radial transmission relation to the piston and having an annular extension, and a knob in radial transmission relation to the member and slidably mounted axially to the measurement chamber;

mounting an axial spring along the inner length of the member, the spring abutting one end of the piston;

providing a sleeve slidably mounted with a portion of the length of the measurement chamber, the sleeve having a radial recess for mating receipt of the annular extension of the member;

providing a needle in liquid communication with the measurement chamber;

rotating the knob to a desired setting thereby causing liquid drug to aspirate from the first chamber into the measurement chamber to reach a measured volume; and

pushing the knob axially inward relative to the measurement chamber thereby causing the annular extension to be received into the radial recess in the sleeve, thereby causing axial extension of the spring against the piston and flow of liquid drug from the measurement chamber and through the needle.