Communication system for automatic synthesis apparatus

• US 6,689,324 B2
• Filed: 02/08/2001
• Issued: 02/10/2004
• Est. Priority Date: 03/21/2000
• Status: Expired due to Fees

• Current Assignee: Shimadzu Corporation
• Original Assignee: Shimadzu Corporation
• Inventors: Inoue, Takaaki
• Primary Examiner(s): Warden, Jill
• Assistant Examiner(s): Handy, Dwayne K
• Application Number:
  US09/778,939
• Publication Number:
  US 20010024465A1
• Time in Patent Office: 1,097 Days
• Field of Search: 422/99, 422/105, 422/107, 422/119, 422/129, 422/130, 422/131, 700/95, 700/96, 700/108, 700/110, 700/266, 700/268, 700/269, 700/274, 702/19, 702/22, 702/81, 702/82, 702/83, 702/84, 702/182, 702/183, 702/184, 702/185
• US Class Current: 422/130
• CPC Class Codes: B01J 19/0046 Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays synthesis methods per se C40B50/00
• CPC Class Codes: B01J 2219/00286 Reactor vessels with top and bottom openings
• CPC Class Codes: B01J 2219/00308 interchangeably mounted in racks or blocks
• CPC Class Codes: B01J 2219/0031 the racks or blocks being mounted in stacked arrangements
• CPC Class Codes: B01J 2219/00313 the reactor vessels being formed by arrays of wells in blocks
• CPC Class Codes: B01J 2219/00335 Septa
• CPC Class Codes: B01J 2219/00376 in multiple or parallel arrangements
• CPC Class Codes: B01J 2219/00454 by chemical cleavage from the solid support
• CPC Class Codes: B01J 2219/00484 by shaking, vibrating or oscillating of the reaction vessels
• CPC Class Codes: B01J 2219/00493 by sparging or bubbling with gases
• CPC Class Codes: B01J 2219/00585 Parallel processes
• CPC Class Codes: B01J 2219/0059 Sequential processes
• CPC Class Codes: B01J 2219/00596 Solid-phase processes
• CPC Class Codes: B01J 2219/00689 using computers
• CPC Class Codes: B01J 2219/00695 Synthesis control routines, e.g. using computer programs
• CPC Class Codes: C40B 50/14 Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
• CPC Class Codes: C40B 60/14 for creating libraries
• CPC Class Codes: G05B 15/02 electric

Abstract

A communication system for automatic synthesis apparatus is formed of an automatic synthesis apparatus and a computer connected to the automatic synthesis apparatus. The automatic synthesis apparatus has a reaction block to produce synthetic compounds along synthesis procedures, and an operation notification creation device for creating operation notification mails according to operating conditions in the synthesis procedures. The computer includes a per-operation transmission setting device for setting to the automatic synthesis apparatus as to whether transmissions of the operation notification mails along the synthesis procedures to the computer are performed or not, and an operation notification mail display device for displaying the operation notification mail. The operating conditions can be monitored by the operation notification mail display device as desired.

Claims

1. A communication system for automatic synthesis apparatus, comprising:

an automatic synthesis apparatus having a reaction block to produce synthetic compounds based on synthesis procedures, operation notification creation means for creating operation notification mails according to operating conditions in the synthesis procedures, and error notification creation means for creating an error notification mail when an error occurs during the procedure, and

a computer electrically connected to the automatic synthesis apparatus and including per-operation transmission setting means for setting to the automatic synthesis apparatus as to whether transmissions of the operation notification mails along the synthesis procedures to the computer are performed or not, operation notification mail display means for displaying the operation notification mail transmitted from the automatic synthesis apparatus by the per-operation transmission setting means, and error notification mail display means for displaying the error notification mail created by the error notification creation means and transmitted from the automatic synthesis apparatus.

2. A communication system according to claim 1, wherein said operation notification creation means creates operation notification mails along the operating conditions in the synthesis procedures so that the operating conditions can be monitored sequentially as desired by the operation notification mail display means.

3. A communication system according to claim 2, wherein said automatic synthesis apparatus further includes a plurality of reaction vessels for performing the synthesis reactions, a plurality of kinds of reagents and solvents to be distributed to the reaction vessels, and means for providing the reagents and solvents to the reaction vessels.

4. A communication system according to claim 1, wherein said operation notification creation means creates the operation notification mails entirely along the synthesis procedures, and said per-operation transmission setting means selects the operation notification mails created at the operation notification creation means so that the operation notification mails selected at the operation transmission setting means are only transmitted to the display means.