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Devices and methods for pain management

  • US 6,689,373 B2
  • Filed: 11/26/2002
  • Issued: 02/10/2004
  • Est. Priority Date: 03/18/1999
  • Status: Expired due to Fees
First Claim
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1. A method of treating pain in a subject, the method comprising:

  • completely implanting a drug delivery device in a subject at an implantation site selected from the group consisting of a subcutaneous site, a subdermal site, an intramuscular site, an intra-adipose tissue site, and an intra-lymphatic site, wherein the drug delivery device is adapted for controlled release of drug, the device comprising;

    a formulation comprising a drug selected from the group consisting of fentanyl and a fentanyl congener, wherein the drug is in the formulation in an amount for treatment of pain in the subject for a period of at least about 3 days; and

    a housing defining a drug delivery outlet and a reservoir, wherein the formulation is within the reservoir, and the reservoir comprises a biocompatible material impermeable to the formulation; and

    parenterally delivering the formulation to the subject from the reservoir and through the drug delivery outlet whereby the drug enters the systemic circulation and is thereby transported to a site of action, whereby the drug is present at the site of action in an amount sufficient to treat pain.

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