Container closure system

• US 6,695,829 B2
• Filed: 12/12/2000
• Issued: 02/24/2004
• Est. Priority Date: 04/22/1996
• Status: Expired due to Fees

• Current Assignee: Hospira Incorporated (Pfizer Inc.)
• Original Assignee: Abbott Laboratories Incorporated
• Inventors: Hellstrom, Steven P., Tanner, John C. II, Karas, Peter J.
• Primary Examiner(s): Bianco, Patricia
• Application Number:
  US09/735,158
• Publication Number:
  US 20010000347A1
• Time in Patent Office: 1,169 Days
• Field of Search: 604/403, 604/411, 604/414-415, 604/249, 604/905, 604/239, 604/82, 604/83, 604/86-89, 604/90-92, 604/93.01, 215/355, 215/50, 215/53, 215/247, 215/249, 215/294, 215/299, 215/300, 215/370, 215/316, 215/321, 215/DIG.3, 215/250-251, 215/356, 220/377, 220/80, 206/215, 206/219, 206/229, 206/222, 206/DIG.8, 206/828, 141/326, 141/329, 141/27, 141/319, 141/383, 141/301, 141/310, 141/312
• US Class Current: 604/415
• CPC Class Codes: A61J 1/1418 Threaded type
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: Y10S 206/828 Medicinal content
• CPC Class Codes: Y10S 215/03 Medical
• CPC Class Codes: Y10S 604/905 Aseptic connectors or couplings, e.g. frangible, piercable

Abstract

A container closure system for delivering a fluid. The system includes a stopper constructed to seal fluidly a container. A closure member is mounted on an upper surface of the stopper. The closure member includes a base having an upper surface and a lower surface. The closure member further includes an outer wall and an inner wall extending from the upper surface of the base with the inner wall spaced from the outer wall. The base defines therethrough a needle access port between the inner and outer walls. The inner wall defines a chamber therein. The base further defines therethrough an aperture adjacent the chamber defined by the inner wall. A piercing member is movably disposed within the chamber defined by the inner wall. The piercing member has a first end portion and a second end portion, the first end portion being positioned proximally to the stopper. A piercing tip is mounted on the first end portion and is constructed to pierce the stopper. The second end portion of the piercing member is configured to engage a luer inserted into the chamber defined by the inner wall. A channel is defined through the piercing member.

Claims

1. A container closure system comprising:

a closure member configured to be attached to a container, said closure member comprising a base having an upper surface and a lower surface, said closure member further comprising an outer wall and an inner wall spaced from said outer wall, said outer wall and said inner wall extending from said upper surface of said base, said base defining therethrough a needle access port intermediate said inner and outer walls, said inner defining a chamber therein, said base defining therethrough an aperture adjacent said chamber defined by said inner wall;

a stopper means for fluidly sealing said needle access port and said aperture defined by said base of said closure member; and

a piercing member movably disposed within said chamber defined by said inner wall, said piercing having a first end portion and a second end portion, said first end portion of said piercing member positioned proximally to said stopper means, a piercing tip mounted on said first end portion, said piercing tip constructed to pierce said stopper means, said second end portion constructed to engage a luer inserted into said chamber defined by said inner wall, said piercing member further defining a channel therethrough, said channel defined by said piercing member constructed to permit fluid transfer through said piercing member;

a sealing member fluidly sealing said chamber defined by said inner wall from an external environment of said chamber, wherein said closure member and said sealing member have mating threads formed thereon whereby said sealing member can be threadably secured to said closure member.

2. A container closure system in accordance with claim 1, wherein said base of said closure member defines therethrough a plurality of needle access ports intermediate said inner and outer walls.

3. A container closure system in accordance with claim 1, wherein said inner wall has an inner surface configured to engage frictionally a luer inserted into said chamber defined by said inner wall.

4. A container closure system in accordance with claim 3, wherein said second end portion of said piercing member has a terminal end, and wherein said inner surface of said inner wall and said piercing member are configured such that said luer inserted into said chamber defined by said inner wall engages said terminal end of said piercing member in end-to-end abutment.

5. A container closure system in accordance with claim 1, wherein said system further comprises a ferrule having a first leg and a second leg, said first leg engaging said closure member and said second leg configured to engage a container.

6. A container closure system in accordance with claim 1, wherein said sealing member comprises a peelable membrane.

7. A container closure system comprising;

a stopper having an upper surface and a lower surface, said lower surface configured to seal fluidly an aperture of a container;

a closure member mounted on said upper surface of said stopper, said closure member comprising a base having an upper surface and a lower surface, said closure member further comprising an outer wall and an inner wall spaced from said outer wall, said outer wall and said inner wall extending from said upper surface of said base, said lower surface of said base constructed to engage said upper surface of said stopper, said base defining therethrough a needle access port intermediate said inner and outer walls, said inner wall defining a chamber therein, said base defining therethrough an aperture adjacent said chamber defined by said inner wall; and

a piercing member movably disposed within said chamber defined by said inner wall, said piercing member having a first end portion and a second end portion, said first end portion of said piercing member positioned proximally to said stopper, a piercing tip mounted on said first end portion, said piercing tip constructed to pierce said stopper, said second end portion constructed to engage a luer inserted into said chamber defined by said inner wall, said piercing member further defining a channel therethrough, said channel defined by said piercing member constructed to permit fluid transfer through said piercing member;

and a sealing member fluidly sealing said chamber defined by said inner wall from an external environment of said chamber, wherein said closure member and said sealing member have mating threads formed thereon whereby said sealing member can be threadably secured to said closure member.

8. A container closure system in accordance with claim 7, wherein said inner wall has an inner surface configured to engage frictionally a luer inserted into said chamber defined by said inner wall.

9. A container closure system in accordance with claim 8, wherein said second end portion of said piercing member has a terminal end, and wherein said inner surface of said inner wall and said piercing member are configured such that a luer inserted into said chamber defined by said inner wall engages said terminal end of said piercing member in end-to-end abutment.

10. A container closure system comprising:

a closure member configured to be attached to a container, said closure member comprising a base having an upper surface and a lower surface, said closure member further comprising an outer wall and an inner wall spaced from said outer wall, said outer wall and said inner wall extending from said upper surface of said base, said base defining therethrough a needle access port intermediate said inner and outer walls, said inner wall defining a chamber therein, said base defining therethrough an aperture adjacent said chamber defined by said inner wall and a plurality of needle access ports intermediate said inner and outer walls;

a stopper means for fluidly sealing said needle access port and said aperture defined by said base of said closure member; and

a piercing member movably disposed within said chamber defined by said inner wall, said piercing member having a first end portion and a second end portion, said first end portion of said piercing member positioned proximally to said stopper means, a piercing tip mounted on said first end portion, said piercing tip constructed to pierce said stopper means, said second end portion constructed to engage a luer inserted into said chamber defined by said inner wall, said piercing member further defining a channel therethrough, said channel defined by said piercing member constructed to permit fluid transfer through said piercing member.

11. A container closure system in accordance with claim 10, wherein said inner wall has an inner surface configured to engage frictionally a luer inserted into said chamber defined by said inner wall.