Inflatable catheter for selective organ heating and cooling and method of using the same

• US 6,695,873 B2
• Filed: 03/11/2002
• Issued: 02/24/2004
• Est. Priority Date: 01/23/1998
• Status: Expired due to Term

• Current Assignee: Zoll Circulation Incorporated (Asahi Kasei Corporation)
• Original Assignee: Innercool therapies Incorporated (Taxus Cardium Pharmaceuticals Group, Inc.)
• Inventors: Lasheras, Juan C., Dobak, John D. III
• Primary Examiner(s): ROLLINS, ROSILAND STACIE
• Application Number:
  US10/095,753
• Publication Number:
  US 20020095200A1
• Time in Patent Office: 715 Days
• Field of Search: 128/898, 607/96, 607/104, 607/105, 607/106, 607/113, 606/20-24, 604/113, 604/104-106, 604/96.01, 604/97.01, 604/101.1, 604/101.02, 604/101.04, 604/101.05, 604/103.07, 604/103.08
• US Class Current: 607/105
• CPC Class Codes: A61B 18/02 by cooling, e.g. cryogenic techniques devices for cooling specific reflex points of the body within cell-life limits A61H39/06
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2018/0022 Balloons
• CPC Class Codes: A61B 2018/0212 using an instrument inserted into a body lumen, e.g. catheter
• CPC Class Codes: A61B 2018/0262 using a circulating cryogenic fluid
• CPC Class Codes: A61F 2007/0056 for cooling
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities

Abstract

A catheter system and method are provided which change the temperature of a fluid, such as blood, by heat transfer. Selective cooling or heating of an organ may be performed by changing the temperature of the blood feeding the organ. The catheter system includes an inlet lumen and an outlet lumen structured and arranged to carry a working fluid having a temperature different from the adjacent blood. The outlet lumen is configured to induce turbulence in the adjacent fluid passing adjacent the outlet lumen.

Claims

1. A catheter method of inducing a therapeutic state of hypothermia in a patient, comprising:

inserting an inflatable heat transfer element, formed by at least an inlet lumen and an outlet lumen, into an artery or vein;

inflating the inflatable heat transfer element by delivering a working fluid to the inflatable heat transfer element, the temperature of the working fluid lower than that of the blood; and

inducing turbulence in the working fluid by passing the working fluid through a helical turbulence-inducing path formed by the outlet lumen, wherein the circulating working fluid is removed from the heat transfer clement by passing through the helical turbulence-inducing path of the outlet lumen, thereby enhancing heat transfer between the circulating fluid and the blood.

2. The method of claim 1, wherein the temperature of the working fluid is between about −

3°

C. and 36°

C.

3. A catheter method of inducing a therapeutic slate of hypothermia in a patient, comprising:

inserting an inflatable heat transfer element, formed by at least an inlet lumen and an outlet lumen, into an artery or vein;

inflating the inflatable beat transfer element by delivering a working fluid to the inflatable heat transfer element, the temperature of the working fluid lower than that of the blood, and

passing the working fluid through a helical turbulence-inducing path formed by the outlet lumen, wherein an open path between the inlet lumen and the outlet lumen allows blood flow therethrough, thereby enhancing heat transfer between the working fluid and the blood.

4. A catheter method of inducing a therapeutic state of hypothermia in a patient, comprising:

inserting an inflatable heat transfer element, formed by at least an inlet lumen and an outlet lumen, into an artery or vein,

inflating the inflatable heat transfer element by delivering a working fluid to the inflatable heat transfer element, the temperature of the working fluid lower than that of the blood; and

passing the working fluid through a helical turbulence-inducing path formed by the outlet lumen wherein the working fluid does not contact an exterior surface of the inlet lumen when passing through the helical turbulence-inducing path, thereby enhancing heat transfer between the working fluid and the blood.