Implantable stimulation device and method for detecting capture of a heart chamber using cross-chamber conducted depolarization

• US 6,697,673 B1
• Filed: 09/13/2001
• Issued: 02/24/2004
• Est. Priority Date: 09/13/2001
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Lu, Richard
• Primary Examiner(s): LAYNO, CARL HERNANDZ
• Application Number:
  US09/952,728
• Time in Patent Office: 894 Days
• Field of Search: 607/9,28
• US Class Current: 607/28
• CPC Class Codes: A61N 1/371 Capture, i.e. successful stimulation
• CPC Class Codes: A61N 1/3714 Atrial capture

Abstract

An implantable cardiac stimulation device and associated method to verify capture of a stimulated atrial site by detecting a conducted depolarization at another atrial site or in the opposite atrial chamber. A signal received during an atrial capture detection window is compared to a depolarization signal threshold or to a depolarization signal template in order to verify detection of a conducted depolarization signal as evidence of capture at the stimulated site. By sensing depolarization signal away from the stimulated site, the negative effects of lead polarization normally encountered when detecting an evoked response are avoided.

Claims

1. A method of verifying capture of a first chamber for use in a cardiac stimulation device, the method comprising:

delivering a stimulation pulse to a first chamber;

setting a capture detection window following the deliver of the stimulation pulse; and

detecting, within a coronary sinus region, a depolarization signal of a second chamber during the capture detection window for verifying capture of the first chamber;

wherein the step of setting the capture detection window includes;

starting the capture detection window after a predetermined delay following the delivery of the stimulation pulse; and

extending the capture detection window beyond an expected inter-chamber conduction time required for an evoked depolarization signal at the first chamber to travel to the second chamber.

2. The method of claim 1, wherein the step of extending the capture detection window includes setting a duration of the capture detection window for approximately 20 msec to 50 msec, beyond the inter-chamber expected conduction time.

3. A method of verifying capture of a first chamber for use in a cardiac stimulation device, the method comprising:

delivering a stimulation pulse to a first chamber;

setting a capture detection window following the delivery of the stimulation pulse; and

detecting, within a coronary sinus region, a depolarization signal of a second chamber during the capture detection window for verifying capture of the first chamber; and

verifying loss of capture of the first chamber if a depolarization signal of the second chamber is not detected.

4. The method of claim 3, wherein delivering a stimulation pulse comprises delivering a stimulation pulse to a first atrial chamber, and wherein detecting a depolarization signal comprises detecting a depolarization signal of a second atrial chamber.

5. The method of claim 4, further including the step of confirming capture of the first atrial chamber when capture is verified.

6. The method of claim 4, further including the step of increasing the stimulation pulse energy at the first atrial chamber if loss of capture is verified.

7. The method of claim 4, further including the step of decreasing the stimulation pulse at the first atrial chamber if capture is verified.

8. The method of claim 3, wherein delivering a stimulation pulse comprises delivering a stimulation pulse to a first ventricular chamber, and wherein detecting a depolarization signal comprises detecting a depolarization signal of a second ventricular chamber.

9. A cardiac stimulation device for verifying capture of a first chamber, comprising:

a pulse generator that selectively generates stimulation energy;

a lead, connected to the pulse generator, that delivers the stimulation energy to the first chamber;

a timing circuit that sets a capture detection window in response to the delivery of the stimulation pulse; and

a sensor that is adapted to be placed in a coronary sinus region and that is operative to detect a depolarization signal of a second chamber during the capture detection to verify capture of the first chamber;

wherein the timing circuit starts the capture detection window at a predetermined delay following the delivery of the stimulation energy.

10. The device of claim 9, wherein the capture detection window extends beyond an inter-chamber expected conduction time required for an evoked depolarization signal at the first chamber to travel to the second chamber.

11. The device of claim 10, wherein the capture detection window extends for approximately 10 msec to 20 msec beyond the inter-chamber expected conduction time.

12. A cardiac stimulation device for verifying capture of a first chamber, comprising:

a pulse generator that selectively generates stimulation energy;

a lead, connected to the pulse generator, that delivers the stimulation energy to the first chamber;

a timing circuit that sets a capture detection window in response to the delivery of the stimulation pulse; and

a sensor that is adapted to be placed in a coronary sinus region, the sensor operative to detect a depolarization signal of a second chamber during the capture detection to verify capture of the first chamber, and the sensor to verify loss of capture of the first chamber if a depolarization signal of the second chamber is not detected.

13. The device of claim 12, wherein the lead is designed to deliver a stimulation pulse to a first atrial chamber, and wherein the sensor is designed to sense depolarization of a second atrial chamber.

14. The device of claim 12, wherein the lead is designed to deliver a stimulation pulse to a first ventricular chamber, and wherein the sensor is designed to sense depolarization of a second ventricular chamber.

15. A cardiac stimulation device for verifying capture of a first chamber, comprising:

means for delivering stimulation energy to the first chamber;

means for setting a capture detection window following the delivery of stimulation energy to the first chamber; and

means for detecting depolarization of a second chamber in a coronary sinus region, during the capture detection window, to verify capture of the first chamber;

wherein the capture detection window extends for approximately 10 msec to 20 msec beyond the inter-chamber expected conduction time.

16. A cardiac stimulation device for verifying capture of a first chamber, comprising:

means for delivering stimulation energy to the first chamber;

means for setting a capture detection window following the delivery of stimulation enemy to the first chamber; and

means for detecting depolarization of a second chamber in a coronary sinus region, during the capture detection window, to verify capture of the first chamber;

wherein the means for detecting the conducted depolarization at the second chamber in response to the stimulation of the first chamber includes a unipolar electrode configuration.

17. A cardiac stimulation device for verifying capture of a first chamber, comprising:

means for delivering stimulation energy to the first chamber;

means for setting a capture detection window following the delivery of stimulation energy to the first chamber; and

means for detecting depolarization of a second chamber in a coronary sinus region, during the capture detection window, to verify capture of the first chamber;

wherein the verifying means verifies capture of the first chamber if a conducted depolarization is detected; and

wherein the verifying means verifies loss of capture of the first chamber if the conducted depolarization is not detected.

18. The device of claim 17, further including means for comparing a morphology of an intracardiac electrogram signal to a morphology of the depolarization template to confirm capture.

19. The device of claim 17, wherein the conducted depolarization includes a conducted depolarization of the second chamber along an inter-chamber path in response to the stimulation of the first chamber.

20. The device of claim 17, wherein the means for detecting the conducted depolarization at the second chamber in response to the stimulation of the first chamber includes a bipolar electrode configuration.

21. The device of claim 17, wherein the means for delivering stimulation energy comprises means for delivering a stimulation pulse to a first atrial chamber, and wherein the means for detecting depolarization comprises means for detecting depolarization of a second atrial chamber.

22. The device of claim 17, wherein the means for delivering stimulation energy comprises means for delivering a stimulation pulse to a first ventricular chamber, and wherein the means for detecting depolarization comprises means for detecting depolarization of a second ventricular chamber.