Contoured syringe and novel luer hub and methods for embolizing blood vessels

• US 6,699,222 B1
• Filed: 11/23/1998
• Issued: 03/02/2004
• Est. Priority Date: 06/13/1997
• Status: Expired due to Term

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Micro Therapeutics, Inc. (Medtronic Plc)
• Inventors: Greff, Richard J., Jones, Michael L.
• Primary Examiner(s): Bennett, Henry
• Assistant Examiner(s): PATEL, NIHIR B
• Application Number:
  US09/197,525
• Time in Patent Office: 1,926 Days
• Field of Search: 604/174, 604/180, 604/187, 604/181, 604/93.01
• US Class Current: 604/187
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61M 31/00 Devices for introducing or retaining media, e.g. remedies, in cavities of the body A61M25/00 takes precedence ; introducing or retaining ophthalmic products into the ocular cavities A61F9/0008
• CPC Class Codes: A61M 31/007 Injectors for solid bodies, e.g. suppositories
• CPC Class Codes: A61M 35/003 Portable hand-held applicators having means for dispensing or spreading integral media hand-held massage devices with liquid delivery A61H7/003
• CPC Class Codes: A61M 37/0069 Devices for implanting pellets, e.g. markers or solid medicaments for introducing of radioactive sources for interstitial radiation therapy, i.e. brachytherapy A61N5/1027

Abstract

Disclosed are novel syringes and catheters for delivering compositions which form solid masses in vivo. These syringes and catheters are particularly useful for delivering embolizing compositions intravascularly.

Claims

1. A syringe/catheter combination comprising:

(a) a catheter comprising a luer hub having a luer hub body for holding a fluid composition, a delivery means attached to the luer hub body, and at least one means for mating the luer hub body to a syringe, and

(b) a syringe comprising a syringe body for holding a fluid composition, an ejection port terminating in said luer hub body, a means for ejecting the fluid composition out of the syringe through said ejection port into said luer hub body, and a means for mating the syringe body to a catheter luer hub such that the dead space arising from mating said syringe body to said catheter is reduced, said means for mating including a taper of a distal end of a wall of the ejection port.

2. A kit of parts comprising:

(1) a syringe which comprises;

(a) a syringe body for holding a fluid material, (b) an ejection port having an annular wall and an orifice which extends from the syringe body to a distal end of said port wherein said annular wall is tapered at the distal end along the length of at least a portion of the ejection port, (c) means, including a luer hub body, for mating said syringe body to a microcatheter, (d) and a means for ejecting a composition in the syringe body through the ejection port into the luer hub body and out of the syringe; and

(2) a microcatheter which mates to the syringe.

3. The kit of parts according to claim 2 which further comprises a composition comprising (a) a biocompatible polymer;

(b) a contrast agent; and

(c) a biocompatible solvent.

6. The kit of parts of claim 2, wherein said annular wall is an inner wall, said taper resulting in an increase in a diameter of said orifice such that said orifice expands away from the syringe body.

7. The kit of parts of claim 2, wherein said annular wall is an outer wall, said taper resulting in a contour which matches an interior contour of the luer hub body.

4. A kit of parts comprising:

(1) a syringe which comprises;

(a) a syringe body for holding a fluid material, (b) an ejection port, (c) a means for ejecting a composition in the syringe body through the ejection port and out of the syringe, and (d) a means for mating said syringe body to a microcatheter; and

(2) a microcatheter comprising (a) a luer hub body for holding a fluid material and a catheter delivery line attached to luer hub body wherein the luer hub body has a maximal volumetric capacity of no more than 0.2 cc, and (b) at least one means for mating the luer hub body to a syringe.

5. The kit of parts according to claim 4 which further comprises a composition comprising (a) a biocompatible polymer;

(b) a contrast agent; and

(c) a biocompatible solvent.