Molecular wire injection sensors
First Claim
1. A sensor for sensing the presence of an analyte component, which sensor does not rely on redox mediators, the sensor comprising:
- a substrate that reports reception of mobile charge carriers to an electronic circuit; and
a plurality of active molecular recognition headgroup surfaces hard wired to a surface of the substrate by molecular wires aligned in a non random orientation, wherein when the analyte component contacts the active molecular recognition headgroup surfaces, mobile charge carriers are transferred directly to and through the molecular wires attached to said headgroup surfaces, without redox reaction in the molecular wires, to thereby allow the substrate to sense the presence of the analyte component.
0 Assignments
0 Petitions
Accused Products
Abstract
Disclosed is a sensor for sensing the presence of an analyte component without relying on redox mediators. This sensor includes (a) a plurality of conductive polymer strands each having at least a first end and a second end and each aligned in a substantially common orientation; (b) a plurality of molecular recognition headgroups having an affinity for the analyte component and being attached to the first ends of the conductive polymer strands; and (c) an electrode substrate attached to the conductive polymer strands at the second ends. The electrode substrate is capable of reporting to an electronic circuit reception of mobile charge carriers (electrons or holes) from the conductive polymer strands. The electrode substrate may be a photovoltaic diode.
-
Citations
21 Claims
-
1. A sensor for sensing the presence of an analyte component, which sensor does not rely on redox mediators, the sensor comprising:
-
a substrate that reports reception of mobile charge carriers to an electronic circuit; and
a plurality of active molecular recognition headgroup surfaces hard wired to a surface of the substrate by molecular wires aligned in a non random orientation, wherein when the analyte component contacts the active molecular recognition headgroup surfaces, mobile charge carriers are transferred directly to and through the molecular wires attached to said headgroup surfaces, without redox reaction in the molecular wires, to thereby allow the substrate to sense the presence of the analyte component. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
-
-
11. A method of detecting a concentration of an analyte component in an analyte with a sensor including (i) a substrate that reports reception of mobile charge carriers to an electronic circuit;
- and (ii) a plurality of active molecular recognition headgroup surfaces hard wired to a surface of the substrate by molecular wires aligned in a non random orientation, the method comprising;
contacting said molecular recognition headgroup surfaces with said analyte to directly transfer mobile charge carriers to and through the molecular wires attached to said headgroup surfaces; and
determining whether mobile charge carriers have been transferred to said substrate from said molecular wire to thereby allow the substrate to sense the presence of the analyte component, wherein said mobile charge carriers are transported without redox reaction in the molecular wires. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
- and (ii) a plurality of active molecular recognition headgroup surfaces hard wired to a surface of the substrate by molecular wires aligned in a non random orientation, the method comprising;
-
21. A sensor for sensing the presence of an analyte component, the sensor comprising:
-
a substrate that reports reception of mobile charge carriers to an electronic circuit; and
a plurality of active molecular recognition surfaces hard wired to a surface of the substrate by nucleic acid based wires, wherein when the analyte component contacts the active molecular recognition surfaces, mobile charge carriers are transferred to and through the wires attached to said headgroup surfaces, without redox reaction in the molecular wires to thereby allow the substrate to sense the presence of the analyte component.
-
Specification