Enhanced hybrid cell stent

• US 6,706,061 B1
• Filed: 11/22/2000
• Issued: 03/16/2004
• Est. Priority Date: 06/30/2000
• Status: Active Grant

• Current Assignee: Cardinal Health Switzerland 515 GmbH (Cardinal Health, Inc.)
• Original Assignee: David R. Fischell, Robert E. Fischell, Tim A. Fischell
• Inventors: Fischell, David R., Fischell, Robert E., Fischell, Tim A.
• Primary Examiner(s): Milano, Michael J.
• Assistant Examiner(s): HO, TAN-UYEN THI
• Application Number:
  US09/718,558
• Time in Patent Office: 1,210 Days
• Field of Search: 623/1-5-, 623/1.35, 623/1.36, 623/1.25
• US Class Current: 623/1.15
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91516 the meander having a change in frequency along the band
• CPC Class Codes: A61F 2002/91525 within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/91541 Adjacent bands are arranged out of phase
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2002/91583 by a bridge, whereby at least one of its ends is connected along the length of a strut between two consecutive apices within a band

Abstract

Disclosed is an open cell stent that has adjacent sets of circumferential struts connected by means of highly flexible, undulating, connecting struts. To decrease outward flaring of the circumferential struts when the pre-deployed stent is advance through highly curved vessels, each unconnected strut of the sets of circumferential struts has a decreased longitudinal length as compared to the longitudinal length of the circumferential struts that are connected by the flexible connecting struts. To decrease the propensity for outward flaring of the end set of circumferential struts, the longitudinal length of the end set of circumferential struts is shorter than the longitudinal length of the interior set of circumferential struts. Enhanced features of the circumferential sets of strut members of the stent are also disclosed. Specifically, variable strut width for the curved sections and the diagonal sections of the circumferential sets of strut members can be employed to enhance the stents radial rigidity and to provide enhanced radiopacity of the end sets of strut members compared to the radiopacity of the interior sets of strut members.

Claims

1. A half open, half closed hybrid cell stent in the form of a thin-walled, multi-cellular, tubular structure having a multiplicity of circumferential sets of strut members, each set of strut members being longitudinally separated each from the other, each set of strut members being connected to adjacent sets of strut members by longitudinal connecting links having at least one curved strut therein and each set of strut members forming a closed, ring-like cylindrical portion of the stent, each set of strut members consisting of a multiplicity of connected curved sections and diagonal sections, each curved section having two ends and a center situated there between, at least one set of strut members having at least half of the curved sections within the set of strut members having a tapered shape wherein the width at the center of a curved section with a tapered shape is greater than the width at the ends of a curved section with tapered shape, and no greater than half of the curved sections of each set of strut members connected to the longitudinal connecting links, and

wherein said longitudinal connecting links comprise further comprising a multiplicity of sets of flexible links with each set of flexible links connecting two of the multiplicity of sets of strut members, each set of flexible links consisting of a multiplicity of individual flexible links, each individual flexible link being a single undulating structure that extends generally in the longitudinal direction that is parallel to the stent'"'"'s longitudinal axis and each individual flexible link having two ends, each one of the two ends being fixedly attached to one curved section of the multiplicity of sets of strut elements at an attachment point situated between the center and the end of that curved section.

2. The stent of claim 1 wherein the curved sections of one or more of the sets of strut members have inside and outside surfaces in the shape of circular arcs, each circular arc having a center with the centers of the two arcs being longitudinally displaced one from the other.

3. The stent of claim 1 wherein the width at the center of the curved sections with a tapered shape is at least 0.001 inches greater than the width at the ends of the curved section with tapered shape.

4. The stent of claim 1 wherein all curved sections have a tapered shape.

5. The stent of claim 1 wherein the sets of strut members include end sets of strut members located at each end of the stent and interior sets of strut members positioned between the end sets of strut members, the end sets of strut members having an average length of its diagonal sections that is shorter than the average length of the diagonal sections of the interior sets of strut members.

6. The stent of claim 5 wherein all curved sections of every interior set of strut members have a tapered shape.

7. The stent of claim 5 wherein the curved sections of the end sets of strut members each have a respective strut width, and the strut width at the center of the curved sections of the end sets of strut members is less than the strut width at the center of the curved sections of the interior sets of strut members.

8. The stent of claim 5 wherein the diagonal sections of the interior sets of strut members have a center and two ends, at least one of the diagonal sections of the interior sets of strut members has a tapered shape wherein the width of the at least one diagonal section is different at the center of the diagonal section as compared to the width at either end of that diagonal section.

9. The stent of claim 8 wherein the width of the at least one diagonal section of the interior sets of strut members is less at the center of that diagonal section compared to the width at either end of that diagonal section.

10. The stent of claim 8 wherein the width of the at least one diagonal section of the interior sets of strut members is greater at the center of that diagonal section as compared to the width at either end of that diagonal section.

11. The stent of claim 8 wherein all the diagonal sections of all of the interior sets of strut members have a tapered shape.

12. The stent of claim 5 wherein all of the diagonal sections of the end sets of strut members have a tapered shape.

13. The stent of claim 12 wherein the tapered diagonal sections of the ends of strut members having a tapered shape have a greater width at their center compared to their ends to enhance the radiopacity of the end set of strut members.

14. The stent of claim 1 wherein the stent is coated with a plastic material.

15. The stent of claim 14 wherein the plastic material is parylene.

16. The stent of claim 14 where a drug is attached to the plastic material, the drug being selected from the group that includes Rapamycin, Alkeran, Cytoxan, Leukeran, Cis-platinum, BiCNU, Adriamycin, Doxorubicin, Cerubidine, Idamycin, Mithracin, Mutamycin, Fluorouracil, Methotrexate, Thoguanine, Toxotere, Taxol, Etoposide, Vincristine, Irinotecan, Hycamptin, Matulane, Vumon, Hexalin, Hydroxyurea, Gemzar, Oncoivin and Etophophos.

17. The stent of claim 14 wherein the drug is heparin.

18. The stent of claim 14 wherein the plastic material has a highly radiopaque material mixed into the plastic material to form a radiopacity coating.

19. The stent of claim 17 wherein the radiopaque material is powdered tungsten.

20. The stent of claim 17 wherein the thickness of the coating is greater on the end set of strut members compared to the thickness of the coating at the longitudinal center of the stent.