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Pulmonary delivery for bioconjugation

  • US 6,706,892 B1
  • Filed: 09/06/2000
  • Issued: 03/16/2004
  • Est. Priority Date: 09/07/1999
  • Status: Expired due to Fees
First Claim
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1. A pharmaceutical composition comprising a compound selected from the group consisting of:

  • a) 2-[2-[4-[(4-chlorophenyl)phenylmethyl[-1-piperazinyl]ethoxy]-maleimido-ethylacetamide;

    b) 11-(N-maleimidopropionyl-4-piperidylidene)-8-chloro-6,11-dihydro-5H-benzo-[5,6]-cyclohepta-[1,2-b]-pyridine;

    c) N-(2-maleimidoethyl)-(1(S)-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl-L-prolinylamide;

    d) N-[2-maleimidoethyl-ε

    -(3,4,5-trimethoxybenzamido)-caproic amide;

    e) Maleimidoethyl-1-theobromineacetamide;

    f) N-(2-maleimidoethyl)-2-[4-(2-oxocyclopentan-1-ylmethyl)phenyl]-propionamide;

    g) N-maleimidopropionyl-N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine;

    h) 4-[N-phenyl-3-maleimidopropionamido]-1-(2-phenylethyl)piperidine; and

    i) N-(2-maleimidoethyl-3,5-3′

    ,5′

    tetraiodothyroninamide.

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