Arrangement in electronically controlled injection devices

• US 6,709,416 B2
• Filed: 10/09/2001
• Issued: 03/23/2004
• Est. Priority Date: 10/20/1995
• Status: Expired due to Fees

• Current Assignee: Pharmacia AB (Pharmacia Corp.)
• Original Assignee: Pharmacia AB (Pharmacia Corp.)
• Inventors: Hjertman, Birger
• Primary Examiner(s): Robert, Eduardo C.
• Application Number:
  US09/971,576
• Publication Number:
  US 20020058912A1
• Time in Patent Office: 896 Days
• Field of Search: 604/131, 604/151, 604/152, 604/154, 604/141, 128/DIG.1, 128/DIG.12, 128/DIG.13
• US Class Current: 604/131
• CPC Class Codes: A61M 2205/33 Controlling, regulating or measuring
• CPC Class Codes: A61M 2205/60 with identification means
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/32 Needles; Details of needles pertaining to their connection with syringe or hub infusion needles A61M5/158; Accessories for bringing the needle into, or holding the needle on, the body A61M5/42, A61M5/46 take precedence; guide needles for catheters A61M25/065; Devices for protection of needles apparatus specially adapted for cleaning or sterilising needles A61M5/001

Abstract

In an electronically controlled injection device for the administering of one or more injections from an injection cartridge, the readying of the device for administrating and the subsequent administering therefrom are controlled by an electronic control unit. This control unit comprises a position or attitude sensor which transmits signals to the control unit such that said readying of the device optionally cannot take place unless the longitudinal axis of the injection cartridge is oriented in a predetermined direction.

Claims

1. A portable or hand-held injection device comprising a container and an injectable preparation, or components for a preparation, an outlet for the preparation and displacing means at least able to displace the preparation through the outlet, wherein the device further comprises a position sensor designed to emit one or more position signals indicative of its orientation and a control unit designed to receive the position signals and issue one or more operation signals for the device, the operation signals being one or more signals controlling the displacing means during readying of the device, so that activation of the displacing means is prevented unless the device is oriented in a predetermined direction.

2. The device of claim 1, characterized in that the container may contain gas and that the operation signals prevent displacing means activation when device orientation is in first predetermined positions unsuitable for deaeration and to allow displacing means activation when device orientation is in second predetermined positions suitable for deaeration.

3. The device of claim 1, characterized in that the container comprises at least two compartments for components of the preparation, that the displacing means are operative to mix contents of at least two compartments and that the operation signals to prevent displacing means activation when device orientation is in first predetermined positions unsuitable for mixing and to allow displacing means activation when device orientation is in second predetermined positions suitable for mixing.

4. The device of claim 3, characterized in that the container is a dual or multi-chamber cartridge with at least one movable piston separating the compartments and a by-pass section for overflow of compartment content past the piston.

5. The device of claim 4, characterized in that the orientation suitable for mixing is with the outlet pointing upward, substantially vertical.

6. The device of claim 1, characterized in that the control unit is designed to register a change in position sensor signals.

7. The device of claim 6, characterized in that the operation signals prevent displacing means activation for ejection of preparation through the outlet unless the device has been turned in a predetermined manner.

8. The device of claim 6, characterized in that the operation signals are designed to prevent repeated displacing means activation for ejection of preparation through the outlet unless the device has been turned in a predetermined manner between the repeated displacement means activations.

9. The device of claim 1, characterized in that the operation signals are designed to prevent displacing means activation for ejection of preparation through the outlet when device orientation is in first predetermined positions unsuitable for administration and to allow displacing means activation for ejection of preparation through the outlet when device orientation is in second predetermined positions suitable for administration.

10. The device of claim 1, characterized in that the operation signals produce one or more alarms or instructions detectable by an operator, for guidance of the operator to the actions stated.

11. The device of claim 1, characterized in that the displacing means are activated by actuating means and that the one or more operation signals are one or more control signals for the actuating means.

12. The device of claim 11, characterized in that the actuating means comprises electric motor means for the displacing means.

13. The device of claim 1, characterized in that the displacing means incorporates arming means, valve-means or fluid control means and that the one or more operation signals are one or more control signals for said arming means, valve-means or fluid control means.

14. An injection device, comprising:

an injection cartridge containing an injectable preparation or components for a preparation which is positioned in a holder and has a rear end,

a piston provided at the rear end of the injection cartridge that is displaceable forward by a piston rod,

an electronic control unit that readies the injection device after positioning said cartridge in the holder,

wherein said electronic control unit comprises a position sensor that emits position signals controlling the control unit during the readying of the device, so that forward movement of the piston rod is prevented unless a longitudinal axis of the injection cartridge is oriented in a predetermined direction.

15. The injection device of claim 14, wherein the movement of the piston rod is effected by means of an electric motor, which is controlled by said control unit.

16. The injection device of claim 14, wherein readying of the device comprises removal of gas from said injection cartridge.

17. The injection device of claim 14, having a multi-chamber cartridge and wherein said readying comprises reconstitution of an injectable composition.

18. The injection device of claim 17, wherein said readying is possible only with a longitudinal axis of the injection cartridge in an essentially vertical orientation, with its front end, from which the injection takes place, pointing upward.

19. The injection device of claim 17, wherein said readying is possible only with a longitudinal axis of the injection cartridge in an essentially vertical orientation, with the front end of the cartridge pointing downwards.