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DNA chip, PNA chip, and their preparation methods

  • US 6,713,255 B1
  • Filed: 06/07/2000
  • Issued: 03/30/2004
  • Est. Priority Date: 06/07/1999
  • Status: Active Grant
First Claim
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1. A DNA chip comprising a solid carrier and a plurality of DNA fragments having one end fixed onto the solid carrier, wherein a plurality of short chain spacer molecules selected from the group consisting of 2-mercaptoethanol, 3-mercaptopropanol and N,N′

  • -di(3-hydroxy-n-propyl)limidazole-2-thione are fixed through a sulfur atom of the molecule onto a surface area of the solid carrier having no DNA fragments thereon.

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