Fluorescent endoscope apparatus

• US 6,716,162 B2
• Filed: 04/24/2001
• Issued: 04/06/2004
• Est. Priority Date: 04/24/2000
• Status: Expired due to Fees

• Current Assignee: Fujifilm Corporation (Fujifilm Holdings Corporation)
• Original Assignee: Fuji Photo Film Co Limited (Fujifilm Holdings Corporation)
• Inventors: Hakamata, Kazuo
• Primary Examiner(s): Leubecker, John P.
• Application Number:
  US09/840,457
• Publication Number:
  US 20030045777A1
• Time in Patent Office: 1,078 Days
• Field of Search: 600/160, 600/178, 600/476, 600/181, 359/656, 359/722, 359/723, 359/350, 359/361, 359/355, 359/359
• US Class Current: 600/181
• CPC Class Codes: A61B 5/0071 by measuring fluorescence emission
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence
• CPC Class Codes: A61B 5/0086 using infrared radiation

Abstract

A fluorescent endoscope apparatus in which the fluorescent light, which becomes noise, emitted from the photographic element propagating the autofluorescent light emitted from a living-tissue subject is reduced, and by which it is possible to clearly distinguish between normal and diseased tissues. The fluorescent endoscope apparatus has a stimulating light projecting unit for irradiating a living-tissue subject with stimulating light, and an optical element for propagating the autofluorescent light emitted from the living tissue subject that has been irradiated by stimulating light. It also has a photographing element, which is formed of the optical element, for photographing the autofluorescent light emitted by the living tissue subject irradiated by the stimulating light. The optical element is structured so as to satisfy the condition expressed by the formula: the strength of the autofluorescent light of normal tissue≧the strength of the autofluorescent light of the optical element×10⁴.

Claims

1. A fluorescent endoscope apparatus comprising a stimulating light projecting means for irradiating a living-tissue subject with stimulating light, and a photographing means formed of an optical element for transferring the autofluorescent light emitted from the live-subject tissue upon irradiation thereof by stimulating light and a photographing element for photographing the autofluorescent light transferred thereto by said optical element, wherein:

said optical element is constructed so that the relationship of the normal-tissue fluorescent light of a strength K, which is the strength of the autofluorescent light emitted from the normal tissue of the live-tissue subject that has been transferred through said optical element and received by the photographing element, to the optical-element fluorescent light of a strength B, which is the strength of the fluorescent light emitted by said optical element when the reflected stimulating light reflected from the living tissue subject upon irradiation thereof by stimulating light is propagated through said optical element, satisfies the condition expressed by the formula;

K≧

B×

10⁴;

said photographing element is provided with a stimulating light cutoff filter for selectively cutting off said stimulating light;

said stimulating light cutoff filter is provided with a panel of optical glass and a multiple layer dielectric film formed thereon;

said optical element comprises a plurality of optical element components; and

wherein

said multiple-layer dielectric film and at least one of said optical element components through which the autofluorescent light is passed and which is disposed between said multiple-layer dielectric film and the living-tissue subject has properties satisfying the condition expressed by the following formulae;

2. The fluorescent endoscope apparatus as defined in claim 1, wherein said stimulating light has a wavelength of 445 nm or smaller.

3. The fluorescent endoscope apparatus as defined in claim 2, wherein

the stimulating light source comprises one of a GaN semiconductor laser, a mercury lamp, a xenon lamp, and a metal halide lamp.