Medical device for injecting liquid

• US 6,716,193 B1
• Filed: 06/17/1999
• Issued: 04/06/2004
• Est. Priority Date: 12/18/1996
• Status: Expired due to Term

• Current Assignee: SMC-Swiss Medical Care S.A.
• Original Assignee: Debiotech S.A.
• Inventors: Neftel, Frédéric
• Primary Examiner(s): Hayes, Michael J.
• Application Number:
  US09/331,350
• Time in Patent Office: 1,755 Days
• Field of Search: 604/67, 604/93.01, 604/167-1-1, 604/246-250, 604/256, 604/65, 604/523, 604/533, 604/30-34, 604/48, 604/80, 604/89, 604/118, 604/131, 604/151, 604/153, 604/257, 604/258, 137/215, 137/217, 137/605, 137/613, 137/877, 600/431, 600/432, 600/433
• US Class Current: 604/118
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps

Abstract

The invention relates to a device for injecting liquid, comprising a piece of tubing on which there is situated at least a first liquid occlusion system. According to the invention, a regulation system (4) is situated upstream from the first occlusion system, the two systems defining an intermediate segment in which the pressure, in the absence of injection, is greater than the pressure that exists downstream from the first occlusion system so as to direct any leak of liquid from the first occlusion system downstream. The invention is applicable to a pump used for injecting contrast liquid for medical imaging.

Claims

1. A device for injecting liquid under pressure to a patient, the device comprising:

means for pumping the liquid,

a length of tubing extending from the pumping means to the patient;

a regulation system located on the length of tubing;

a first occlusion system located on the length of tubing downstream of the regulation system, the first occlusion system and the regulation system defining an intermediate segment having an intermediate pressure, a segment of tubing downstream of the first occlusion system having a downstream pressure, wherein the intermediate pressure, in the absence of injection to the patient, is greater than the downstream pressure to direct leakage of liquid from the first occlusion system downstream toward the patient;

a first pressure sensor connected to the intermediate segment which measures any drop in the intermediate pressure in the absence of injection to the patient to detect leakage from the intermediate segment, the first pressure sensor having an output indicative of leakage from the intermediate segment, said output being operative in the absence of injection to the patient;

means responsive to the output of the first pressure sensor for assisting in prevention of contamination of components upstream of the first occlusion system; and

a disconnection system situated on the intermediate segment, said disconnection system comprising a boundary between a piece of tubing downstream therefrom for single use and a piece of tubing upstream therefrom for multiple use, wherein said disconnection system further comprises means for occluding at least one piece of the tubing that is activated prior to disconnection.

2. The device according to claim 1, wherein said disconnection system comprises two mutually mated pieces which enable the occlusion means to be activated or deactivated only if the mating of one piece complies with that of the other.

3. The device according to claim 2, wherein said occlusion means includes a septum mounted to at least one of the two pieces, said septum being structured to open automatically when the two pieces are engaged in a sealed manner.

4. The device according to claim 3, wherein the septum is structured to close in a sealed manner when the two pieces are disengaged.

5. A device for injecting liquid under pressure to a patient, the device comprising:

means for pumping the liquid;

a length of tubing extending from the pumping means to the patient;

a regulation system located on the length of tubing;

a first occlusion system located on the length of tubing downstream of the regulation system the first occlusion system and the regulation system defining an intermediate segment having an intermediate pressure, a segment of tubing downstream of the first occlusion system having a downstream pressure wherein the intermediate pressure, in the absence of injection to the patient is greater than the downstream pressure to direct leakage of liquid from the first occlusion system downstream toward the patient;

a first pressure sensor connected to the intermediate segment which measures any drop in the intermediate pressure in the absence of injection to the patient to detect leakage from the intermediate segment, the first pressure sensor having an output indicative of leakage from the intermediate segment, said output being operative in the absence of injection to the patient; and

means responsive to the output of the first pressure sensor for assisting in prevention of contamination of components upstream of the first occlusion system, wherein the means for assisting includes the means for pumping which is activated in response to the output of the first pressure sensor indicative of leakage from the intermediate segment so as to maintain the intermediate pressure in said intermediate segment at least at a predetermined threshold.

6. A device for injecting liquid under pressure to a patient, the device comprising:

means for pumping the liquid;

a length of tubing extending from the pumping means to the patient;

a regulation system located on the length of tubing;

a first occlusion system located on the length of tubing downstream of the regulation system, the first occlusion system and the regulation system defining an intermediate segment having an intermediate pressure, a segment of tubing downstream of the first occlusion system having a downstream pressure, wherein the intermediate pressure, in the absence of injection to the patient, is greater than the downstream pressure to direct leakage of liquid from the first occlusion system downstream toward the patient;

a first pressure sensor connected to the intermediate segment which measures any drop in the intermediate pressure in the absence of injection to the patient to detect leakage from the intermediate segment, the first pressure sensor having an output indicative of leakage from the intermediate segment, said output being operative in the absence of injection to the patient; and

means responsive to the output of the first pressure sensor for assisting in prevention of contamination of components upstream of the first occlusion system, wherein the means for assisting includes means for modifying the intermediate pressure of said intermediate segment in the absence of injection to the patient so as to obtain an intermediate pressure which lies between the downstream pressure and the opening pressure of the first occlusion system.

7. The device according to claim 6, wherein said means for modifying the intermediate pressure is responsive to the output of the first pressure sensor and activates the means for pumping.

8. The device according to claim 6, wherein said means for modifying includes a syringe driver and a syringe, the syringe forming an integral portion of the intermediate segment.

9. The device according to claim 8, wherein the first pressure sensor is situated at a distal end of a piston of the syringe driver which moves a piston of the syringe.

10. The device according to claim 8, wherein the means for pumping includes the syringe and the syringe driver of said means for modifying the intermediate pressure of the intermediate segment.

11. The device according to claim 6, wherein said means for pumping includes a pump.

12. The device according to claim 11, wherein the means for modifying includes a syringe which forms an integral portion of the intermediate segment, a piston of the syringe constructed to adjust a volume of said intermediate chamber.

13. The device according to claim 11, wherein the means for modifying includes the pump.

14. The device according to claim 6, wherein the means for modifying includes a pump separate from the means for pumping.

15. A device for injecting liquid under pressure to a patient, the device comprising:

means for pumping the liquid;

a length of tubing extending from the pumping means to the patient;

a regulation system located on the length of tubing;

a first occlusion system located on the length of tubing downstream of the regulation system, the first occlusion system and the regulation system defining an intermediate segment having an intermediate pressure, a segment of tubing downstream of the first occlusion system having a downstream pressure, wherein the intermediate pressure, in the absence of injection to the patient, is greater than the downstream pressure to direct leakage of liquid from the first occlusion system downstream toward the patient;

a first pressure sensor connected to the intermediate segment which measures any drop in the intermediate pressure in the absence of injection to the patient to detect leakage from the intermediate segment, the first pressure sensor having an output indicative of leakage from the intermediate segment, said output being operative in the absence of injection to the patient;

means responsive to the output of the first pressure sensor for assisting in prevention of contamination of components upstream of the first occlusion system; and

a disconnection system situated on the intermediate segment, said disconnection system comprising a boundary between a piece of tubing downstream therefrom for single use and a piece of tubing upstream therefrom for multiple use, wherein said upstream piece and said downstream piece are capable of co-operating in releasable manner so as to form a leakproof link, said upstream piece having an intermediate chamber having an internal volume that is adjustable by a moving piston.

16. The device according to claim 15, wherein the piston is structured to increase the internal volume of the upstream piece to obtain a pressure in the upstream piece less than or equal to atmospheric pressure, prior to the upstream piece and downstream piece being fully released.

17. The device according to claim 16, wherein the means for pumping includes a syringe and the piston is a portion of the syringe.

18. The device according to claim 16, wherein the piston is a septum mounted to the intermediate chamber of the upstream piece.

19. The device according to claim 15, wherein the intermediate chamber is in communication with the intermediate segment.

20. The device according to claim 15, wherein the means for pumping includes a syringe.

21. The device according to claim 20, wherein the intermediate chamber includes a volume of the syringe.

22. A device for injecting liquid under pressure to a patient, the device comprising:

means for pumping the liquid;

a length of tubing extending from the pumping means to the patient;

a regulation system located on the length of tubing;

a first occlusion system located on the length of tubing downstream of the regulation system, the first occlusion system and the regulation system defining an intermediate segment having an intermediate pressure, a segment of tubing downstream of the first occlusion system having a downstream pressure, wherein the intermediate pressure, in the absence of injection to the patient, is greater than the downstream pressure to direct leakage of liquid from the first occlusion system downstream toward the patient;

a first pressure sensor connected to the intermediate segment which measures any drop in the intermediate pressure in the absence of injection to the patient to detect leakage from the intermediate segment, the first pressure sensor having an output indicative of leakage from the intermediate segment, said output being operative in the absence of injection to the patient;

means responsive to the output of the first pressure sensor for assisting in prevention of contamination of components upstream of the first occlusion system;

a second pressure sensor situated on a patient tubing segment located downstream from the first occlusion system; and

a measurement system responsive to the output of the first pressure sensor and an output of the second pressure sensor, the measurement system structured to measure a difference in pressure between the pressure in the intermediate segment and the pressure in the patient tubing segment downstream from the first occlusion system in the absence of injection to the patient, wherein the means for assisting includes the means for pumping, wherein in the absence of injection to the patient, the means for pumping is activated in response to measurement of the pressure in the intermediate segment being approximately equal to or less than the pressure in the patient tubing segment downstream from the first occlusion system, so as to maintain the intermediate pressure in the intermediate segment above the pressure in the patient tubing.

23. A device for injecting liquid under pressure to a patient, the device comprising:

means for pumping the liquid;

a length of tubing extending from the pumping means to the patient;

a regulation system located on the length of tubing and having a second opening pressure;

a first occlusion system located on the length of tubing downstream of the regulation system and having a first opening pressure, the first opening pressure being lower than the second opening pressure; and

wherein the first occlusion system and the regulation system define an intermediate segment having an intermediate pressure, a segment of tubing downstream of the first occlusion system having a downstream pressure, wherein the intermediate pressure, in the absence of injection to the patient, is greater than the downstream pressure to direct leakage of liquid from the first occlusion system downstream toward the patient.

24. The device according to claim 23, wherein said first occlusion system includes a non-return valve.

25. The device according to claim 24, wherein said non-return valve comprises a plug capable of being compressed radially so as to allow liquid to bypass it in the event of the pressure of the liquid upstream fro said plug being greater than or equal to the first opening pressure of said non-return valve.

26. The device according to claim 24, wherein said first opening pressure is greater than a closing pressure of the non-return valve.

27. The device according to claim 23, wherein said regulation system includes a second occlusion system.

28. The device according to claim 27, wherein said second occlusion system includes a system involving flattening of the tubing.

29. The device according to claim 28, wherein said means for pumping includes a peristaltic cassette pump and wherein said system for flattening the tubing includes the wheels of the peristaltic cassette pump.

30. The device according to claim 27, wherein said second occlusion system includes a non-return valve.

31. The device according to claim 30, wherein said non-return valve comprises a plug capable of being compressed radially so as to enable it to be bypassed by the liquid when the pressure of the liquid upstream from the plug is greater than or equal to the first opening pressure.

32. The device according to claim 27, wherein said second occlusion system includes an automatic clamp.

33. The device according to claim 27, wherein said second occlusion system includes a system which compresses the tubing.

34. The device according to claim 23, wherein the first opening pressure of the first occlusion system is greater than the intermediate pressure that exists in the intermediate segment in the absence of injection to the patient.

35. The device according to claim 23, further comprising a disconnection system situated on the intermediate segment, said disconnection system comprising a boundary between a piece of tubing downstream therefrom for single use and a piece of tubing upstream therefrom for multiple use.

36. The device according to claim 35, wherein said disconnection system comprises means for occluding at least one piece of the tubing that is structured to be activated prior to disconnection.

37. The device according to claim 36, wherein said disconnection system comprises two mutually mated pieces which enable the occlusion means to be activated or deactivated only if the mating of one piece complies with that of the other.

38. The device according to claim 37, wherein said occlusion means includes a septum mounted to at least one of the two pieces, said septum being structured to open automatically when the two pieces are engaged in a sealed manner.

39. The device according to claim 38, wherein the septum is structured to close in a sealed manner when the two pieces are disengaged.

40. The device according to claim 35, further comprising a first pressure sensor located on the intermediate segment which measures a drop in the intermediate pressure in the absence of injection to the patient to detect leakage from the intermediate segment, the first pressure sensor contacting a multiple use piece of said tubing.

41. The device according to claim 35, wherein said upstream piece and said downstream piece are capable of co-operating in releasable manner so as to form a leakproof link, said upstream piece having an intermediate chamber having an internal volume that is adjustable by a moving piston.

42. The device according to claim 41, wherein the piston is structured to increase the internal volume of the upstream piece to obtain a pressure in the upstream piece less than or equal to atmospheric pressure, prior to the upstream piece and the downstream piece being fully released.

43. The device according to claim 42, wherein the means for pumping includes a syringe and the piston is a portion of the syringe.

44. The device according to claim 42, wherein the piston is a septum mounted to the intermediate chamber of the upstream piece.

45. The device according to claim 41, wherein the intermediate chamber is in communication with the intermediate segment.

46. The device according to claim 41, wherein the means for pumping includes a syringe.

47. The device according to claim 46, wherein the intermediate chamber includes a volume of the syringe.

48. The device according to claim 23, further comprising a first pressure sensor located on the intermediate segment which measures a drop in the intermediate pressure in the absence of injection to the patient to detect leakage from the intermediate segment, the first pressure sensor having an output indicative of leakage from the intermediate segment.

49. The device according to claim 48, further comprising a second pressure sensor situated on a patient tubing segment located downstream from the first occlusion system.

50. The device according to claim 49, further comprising a measurement system responsive to the output of the first pressure sensor and an output of the second pressure sensor, the measurement system structured to measure a difference in pressure between the pressure in the intermediate segment and the pressure in the patient tubing segment downstream from the first occlusion system in the absence of injection to the patient.

51. The device according to claim 50, further comprising an alarm, wherein in the absence of injection to the patient, the alarm is triggered if the pressure in the intermediate segment is approximately equal to or less than the pressure in the patient tubing segment downstream from the first occlusion system.

52. The device according to claim 50, wherein in the absence of injection to the patient, the means for pumping is activated in response to measurement of the pressure in the intermediate segment being approximately equal to or less than the pressure in the patient tubing segment downstream from the first occlusion system, so as to maintain the intermediate pressure in the intermediate segment above the pressure in the patient tubing.

53. The device according to claim 48, further comprising an alarm responsive to the output of the first pressure sensor, wherein in the absence of injection to the patient, the alarm is triggered if the intermediate pressure in the intermediate segment decreases.

54. The device according to claim 53, further comprising a second disconnection system which is situated upstream from the regulation system, the second disconnection system enabling the intermediate segment to be changed in the event of the alarm occurring that is associated with a risk of contamination.

55. The device according to claim 53, wherein the alarm is triggered if the intermediate pressure drops beneath a predetermined value.

56. The device according to claim 48, wherein the means for pumping is activated in response to the output of the first pressure sensor indicative of leakage from the intermediate segment so as to maintain the intermediate pressure in said intermediate segment at least at a predetermined threshold.

57. The device according to claim 48, further comprising an alarm responsive to the output of the first pressure sensor, the alarm being triggered if the intermediate pressure in the intermediate segment increases or if the intermediate pressure rises above a predetermined value.

58. The device according to claim 48, further comprising means for modifying the intermediate pressure of said intermediate segment in the absence of injection to the patient so as to obtain an intermediate pressure which lies between the downstream pressure and the opening pressure of the first occlusion system.

59. The device according to claim 58, wherein said means for modifying the intermediate pressure is responsive to the output of the first pressure sensor and activates the means for pumping.

60. The device according to claim 58, wherein said means for modifying includes a syringe driver and a syringe, the syringe forming an integral portion of the intermediate segment.

61. The device according to claim 60, wherein the first pressure sensor is situated at a distal end of a piston of the syringe driver which moves a piston of the syringe.

62. The device according to claim 60, wherein the means for pumping includes the syringe and the syringe driver of said means for modifying the intermediate pressure of the intermediate segment.

63. The device according to claim 58, wherein said means for pumping includes a pump.

64. The device according to claim 63, wherein the means for modifying includes a syringe which forms an integral portion of the intermediate segment, a piston of the syringe constructed to adjust a volume of said intermediate chamber.

65. The device according to claim 63, wherein the means for modifying includes the pump.

66. The device according to claim 48, further comprising a second pressure sensor measuring the pressure of the liquid in a length of the tubing situated upstream from the intermediate segment.

67. The device according to claim 23, wherein the liquid under pressure includes contrast media.

68. The device according to claim 23, wherein the means for pumping includes a pump.

69. The device according to claim 68, wherein the pump includes a peristaltic cassette pump.

70. The device according to claim 23, wherein the means for pumping includes a syringe.

71. The device according to claim 23, wherein said first occlusion system includes an automatic clamp.

72. The device according to claim 23, wherein the regulation system is located downstream from the means for pumping.

73. The device according to claim 23 wherein the regulation system includes at least an element of the means for pumping.

74. The device according to claim 73, wherein the means for pumping includes a syringe and the regulation system includes a piston of the syringe.