Compositions for efficient release of active ingredients
First Claim
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1. An article, comprising:
- a. a dispensing means; and
b. a release composition applied to at least a portion of the dispensing means, the release composition comprising;
(1) from about 10−
4% to about 20%, by weight of the release composition, of at least one skin care active that is selected from the group consisting of hexamidine and its salts and derivatives, triacetin, phytic acid, ethylenediamine tetraacetic acid, phenylsulfonyl fluorides, Vitamins B3, B5, niacinamide, panthenol, Vitamin C and derivatives, chitosan, and mixtures thereof;
(2) from about 0.1% to about 60%, by weight of the release composition, of a release agent; and
(3) from about 0.1% to about 95%, by weight of the release composition, of a barrier protectant;
wherein the dispensing means is selected from the group consisting of a web substrate, an absorbent article, a tissue, a wipe, a sponge, a cotton ball, a pad, a non-woven substrate, a patch, a bandage, paper, fabric;
wherein the release composition is substantially oleaginous and is at least partially transferable to a wearer'"'"'s skin; and
, wherein the release agent is substantially hydrophilic and oleophilic, has an HLB value of at least about 3 and consists essentially of an ethoxylated C20-C40 fatty alcohol having an average molecular weight of the alcohol chain of at least about 450.
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Abstract
The present invention relates to a novel composition for efficiently releasing hydrophilic or water-soluble skin care actives from an oleaginous composition. The substantially oleaginous composition of the present invention comprises: (1) at least one skin care active; (2) a release agent having an HLB of at least about 3; and (3) a hydrophobic barrier protectant. The novel release composition may be topically applied to skin using a dispensing means such as an absorbent article, a wipe, a bandage, a pad, a canister, a stick, an aerosol dispenser, a sprayer, and the like.
364 Citations
12 Claims
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1. An article, comprising:
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a. a dispensing means; and
b. a release composition applied to at least a portion of the dispensing means, the release composition comprising;
(1) from about 10−
4% to about 20%, by weight of the release composition, of at least one skin care active that is selected from the group consisting of hexamidine and its salts and derivatives, triacetin, phytic acid, ethylenediamine tetraacetic acid, phenylsulfonyl fluorides, Vitamins B3, B5, niacinamide, panthenol, Vitamin C and derivatives, chitosan, and mixtures thereof;
(2) from about 0.1% to about 60%, by weight of the release composition, of a release agent; and
(3) from about 0.1% to about 95%, by weight of the release composition, of a barrier protectant;
wherein the dispensing means is selected from the group consisting of a web substrate, an absorbent article, a tissue, a wipe, a sponge, a cotton ball, a pad, a non-woven substrate, a patch, a bandage, paper, fabric;
wherein the release composition is substantially oleaginous and is at least partially transferable to a wearer'"'"'s skin; and
,wherein the release agent is substantially hydrophilic and oleophilic, has an HLB value of at least about 3 and consists essentially of an ethoxylated C20-C40 fatty alcohol having an average molecular weight of the alcohol chain of at least about 450. - View Dependent Claims (2, 3, 4, 5, 6, 7)
a backsheet;
a topsheet joined to the backsheet;
an absorbent core positioned between the topsheet and the backsheet; and
a cuff joined to the chassis.
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5. The article of claim 1 wherein the skin care active has a water solubility of at least 0.1 gram of skis care active per 100 grams of water at 25°
- C.
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6. The article of claim 1 wherein the barrier protectant is selected from the group consisting of C14-C60 fatty alcohols, C14-C60 fatty acids;
- C14-C60 fatty acid esters;
natural waxes, paraffin waxes;
synthetic waxes;
modified polysiloxanes having alkyl, phenyl or alkylphenyl groups;
animal oils and hydrogenated animal oils and waxes; and
mixtures thereof.
- C14-C60 fatty acid esters;
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7. The article of claim 1 further comprising optional ingredients selected from the group consisting of petroleum based emollients, polyolpolyester, fatty acid ester emollients, vegetable oils, hydrogenated vegetable oils and waxes, humectants, fatty alcohol ethers, talc, topical starch, zinc salts, kaolin, live yeast cell derivatives, microporous cellulose, colloidal oatmeal, cholecalciferol, Peruvean balsam oil, protein hydrlysate, racemic methionine, vitamins, and the like, aloe vera, and mixtures thereof.
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8. A method for effectively delivering one or more skin care actives to skin, comprising:
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(a) applying to the skin an article comprising a dispensing means and a release composition disposed on at least a portion of the dispensing means;
wherein the release composition is substantially oleaginous and comprises;
(1) from about 10−
4% to about 20%, by weight of the release composition, of at least one skin care active that is selected from the group consisting of hexamidine and its salts and derivatives, triacetin, phytic acid, ethylenediamine tetraacetic acid phenylsulfonyl fluorides, Vitamins B3, B5, niacinamide, panthenol, Vitamin C and derivatives, chitosan, and mixtures thereof;
(2) from about 0.1% to about 60%, by weight of the release composition, of a release agent; and
(3) from about 0.1% to about 95%, by weight of the release composition, of a barrier protectant;
wherein the dispensing means is selected from the group consisting of a web substrate, an absorbent article, a tissue, a wipe, a sponge, a cotton ball, a pad, a non-woven substrate, a patch, a bandage, paper, fabric, (b) transferring at least a portion of the release composition to the skin;
(c) exposing the release composition, to moisture; and
(d) releasing one or more skin care active ingredients from the release composition; and
wherein the release agent is substantially hydrophilic and oleophilic, has an HLB value of at least about 3 and consists essentially of an ethoxylated C20-C40 fatty alcohol having an average molecular weight of the alcohol chain of at least about 450.- View Dependent Claims (9, 10, 11)
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12. A method for improving the skin condition of a wearer in an area covered by a treated absorbent article, comprising:
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(a) applying to the wearer an absorbent article, said absorbent article having a release composition applied to at least a portion thereof;
wherein the release composition is substantially oleaginous and comprises;
(1) from about 10−
4% to about 20%, by weight of the release composition, of at least one skin care active that is selected from the group consisting of hexamidine and its salts and derivatives, triacetin, phytic acid, ethylenediamine tetraacetic acid, phenylsulfonyl fluorides, Vitamins B3, B5, niacinamide, panthenol, Vitamin C and derivatives, chitosan, and mixtures thereof;
(2) from about 0.1% to about 60% by weight of the release composition, of a release agent; and
(3) from about 0.1% to about 95% by weight of the release composition, of a barrier protectant and;
wherein the release agent is substantially hydrophilic and oleophilic, has an HLB value of at least about 3 and consists essentially of an ethoxylated C20-C40 fatty alcohol having an average molecular weight of the alcohol chain of at least about 450, (b) transferring at least a portion of the release composition to the wearer while the article is worn;
(c) exposing the release composition to moisture;
(d) releasing the skin care active ingredient from the release composition; and
(e) repeating steps (a-d) with one or more additional treated absorbent articles with sufficient frequency to improve skin condition in the area covered by the treated absorbent article, relative to skin covered by an untreated absorbent article.
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Specification