Method for treating a target volume with a particle beam and device implementing same

• US 6,717,162 B1
• Filed: 06/21/2001
• Issued: 04/06/2004
• Est. Priority Date: 12/24/1998
• Status: Expired due to Term

• Current Assignee: Ion Beam Applications s.a.
• Original Assignee: Ion Beam Applications s.a.
• Inventors: Jongen, Yves
• Primary Examiner(s): Wells, Nikita
• Application Number:
  US09/868,754
• Time in Patent Office: 1,020 Days
• Field of Search: 250/505.1, 250/492.3, 250/492.1, 315/502, 378/65
• US Class Current: 250/505.1
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 5/1042 with spatial modulation of the radiation beam within the treatment head
• CPC Class Codes: A61N 5/1043 Scanning the radiation beam, e.g. spot scanning or raster scanning
• CPC Class Codes: G21K 5/10 with provision for relative movement of beam source and object to be irradiated
• CPC Class Codes: H05H 7/00 Details of devices of the types covered by groups H05H9/00, H05H11/00, H05H13/00

Abstract

The invention concerns a method for treating a target volume with a particle beam, in particular a proton beam, which consists in generating said particle beam using an accelerator and in producing from said beam a narrow spot directed towards the target volume, characterized in that said spot sweeping speed and the particle beam intensity are simultaneously varied.

Claims

1. Process for treating a particle beam (1000) produced by an accelerator in order to irradiate a target volume (0) consisting of for example a tumor to be treated in the case of a cancer, wherein this particle beam (1000) is produced using said accelerator, and a spot (100) located in the target volume is formed from this beam, characterized in that the movement of said spot within the target volume along the three dimensions (X, Y, Z) and the variation of the particle beam intensity are performed simultaneously so that the dose to be delivered conforms to the target volume.

2. Process according to claim 1, characterized in that the movement in the two directions (X, Y) perpendicular to the direction (Z) of the beam defining an irradiation plane takes place continuously by scanning.

3. Process according to claim 2, characterized in that the movement of the spot (100) within the target volume (0) in the two directions (X, Y) perpendicular to the direction (Z) of the beam takes place by varying the scanning speed of said beam.

4. Process according to claim 2, characterized in that the movements in an irradiation plane are effected using two scanning magnets (1 and 2) preferably located in the irradiation head.

5. Process according to claim 4, characterized in that the simultaneous control of the scanning magnets (1 and 2) and of the intensity of the current of the particle beam is performed using an algorithm for planning the trajectories of said particles, combining therewith a regulation loop for real-time correction of said trajectories.

6. Process according to claim 1, characterized in that the target volume is cut into several successive irradiation planes perpendicular to the direction of the beam, corresponding to successive depths, the depthwise movement of the spot from one plane to another being achieved by modifying the energy of the particle beam.

7. Process according to claim 6, characterized in that the energy of the particle beam is modified immediately after extracting it from the accelerator.

8. Process according to claim 1, characterized in that the movement of the spot from one irradiation plane to another is effected by modifying the energy of the particle beam using an energy degrader.

9. Process according to claim 1, characterized in that the movement of the spot is effected without interrupting the beam.

10. Process according to claim 1, characterized in that the contours of the areas in each irradiation plane are controlled by scanning magnets (1 and 2).

11. Process according to claim 1, characterized in that the spot scans each irradiation plane several times.

12. Process according to claim 1, characterized in that the dose corresponding to the spot is defined by predetermining the beam intensity and the scanning speed for each irradiation plane or voxel using a planning and treating data system.

13. Process for treating a cancer tumor afflicting a patient using the process according to claim 1, characterized in that a dose having a conformation corresponding to the volume of the cancer tumor to be treated is delivered to said patient.

14. Device for treating a particle beam produced by an accelerator and devoted to the irradiation of a target volume (0) by a particle beam (1000) according to claim 1, said device comprising a particle accelerator such as a cyclotron for generating a spot (100) located within the target volume (0), combined with scanning means (1 and 2) and in particular scanning magnets for obtaining scanning of said spot in the two directions (X, Y) perpendicular to the direction (Z) of the spot, and means for obtaining a variation in the intensity of said particle beam, characterized in that the scanning means (1, 2) and the means for varying the beam intensity are controlled simultaneously by a planning and regulating algorithm, so that the delivered dose conforms o the target volume.

15. Device according to claim 14, characterized in that it comprises means for obtaining a variation in the energy of said beam in order to obtain a movement of the spot as a function of the depth (Z) of the target volume.

16. Device according to claim 14, characterized in that it comprises at least one detection device such as an ionization chamber (3, 8) and/or a diagnostic element for carrying out measurements in order to verify the conformation of the irradiation dose to the target volume.

17. Device according to claim 14, characterized in that the means for obtaining a variation of the beam energy are located immediately after the extraction of the accelerator.

18. Process for treating a cancer tumor afflicting a patient using the device according to claim 14, characterized in that a dose having a conformation corresponding to the volume of the cancer tumor to be treated is delivered to said patient.

19. Process for treating a particle beam (1000) produced by an accelerator and devoted to the irradiation of a target volume (0) consisting of for example a tumor to be treated in the case of a cancer, wherein the particle beam is produced using a fixed-energy accelerator, and a narrow spot directed towards the target volume is produced from this beam, characterized in that the energy of said particle beam is modified immediately after it is extracted from the accelerator, wherein the movement of a spot (100) within the target volume and the variation of the particle beam intensity are performed simultaneously so that the dose to be delivered conforms to the target volume.

20. Process according to claim 19, wherein the movement of said spot within the target volume is along the three dimensions (X, Y, Z) and the variation of the particle beam intensity are performed simultaneously so that the dose to be delivered conforms to the target volume.