Moulded bodies made of thermoplastic polyurethane containing an active substance

• US 6,723,333 B1
• Filed: 09/15/2000
• Issued: 04/20/2004
• Est. Priority Date: 03/20/1998
• Status: Expired due to Fees

• Current Assignee: Bayer AG
• Original Assignee: Bayer AG
• Inventors: Krasemann-Sharma, Christina, Pudleiner, Heinz, Dujardin, Ralf, Kreiss, Wolfgang, Simon, Joachim, Albers, Reinhard, Eberz, Günther
• Primary Examiner(s): Page, Thurman K.
• Assistant Examiner(s): Bennett, Rachel M.
• Application Number:
  US09/646,339
• Time in Patent Office: 1,313 Days
• Field of Search: 424/422, 424/423, 424/426
• US Class Current: 424/422
• CPC Class Codes: A61L 2300/406 Antibiotics
• CPC Class Codes: A61L 29/06 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 29/16 Biologically active materials, e.g. therapeutic substances A61L29/048 takes precedence
• CPC Class Codes: A61P 31/00 Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• CPC Class Codes: C08G 18/12 using two or more compounds having active hydrogen in the first polymerisation step
• CPC Class Codes: C08G 18/3234 cycloaliphatic
• CPC Class Codes: C08G 18/6674 with compounds of group C08G18/3203
• CPC Class Codes: C08K 5/0058 Biocides; macromolecular substances as carriers for biocide material A01N25/10
• CPC Class Codes: C08L 75/04 Polyurethanes

Abstract

The invention provides moulded items made from thermoplastic polyurethanes (TPUs), in particular medical articles such as central venous catheters which contain a homogeneous distribution of antibiotic substances, a process for the preparation thereof and preparation of the active substance-containing TPUs.

Claims

1. Moulded items made from a thermoplastically processable polyurethane containing a homogeneous distribution of an antibiotic substance which have a peak-to-valley surface roughness of <

5 μ

m.

2. A process for preparing items according to claim 1 by extrusion or injection moulding of a thermoplastically processable polyurethane containing a homogeneous distribution of an antibiotic substance.

3. A process for preparing moulded items according to claim 1 by the mutual extrusion of an antibiotic substance and a thermoplastically processable polyurethane.

4. A medical article comprising the polyurethane of claim 1.