Method and apparatus for differentially perfusing a patient during cardiopulmonary bypass

• US 6,726,651 B1
• Filed: 08/04/1999
• Issued: 04/27/2004
• Est. Priority Date: 08/04/1999
• Status: Expired due to Fees

• Current Assignee: Cardeon Corporation
• Original Assignee: Cardeon Corporation
• Inventors: Robinson, Janine, Olsen, Eric, Young, Lisa M., Lee, Mike, Macoviak, John A., Esch, Brady, Samson, Wilfred J.
• Primary Examiner(s): Hayes, Michael J.
• Application Number:
  US09/368,450
• Time in Patent Office: 1,728 Days
• Field of Search: 604/4, 604/101.01, 604/101-3-1, 604/102.01, 604/102.03, 604/103.1, 604/164.01, 604/164.09, 604/164.1, 604/96.01, 604/264, 604/265, 604/524, 604/533-535, 606/192, 606/194
• US Class Current: 604/101.01
• CPC Class Codes: A61B 17/12045 double occlusion, e.g. during anastomosis
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/12127 Double occlusion, e.g. for creating blood-free anastomosis site
• CPC Class Codes: A61M 1/3613 Reperfusion, e.g. of the coronary vessels, e.g. retroperfusion
• CPC Class Codes: A61M 2025/1015 having two or more independently movable balloons where the distance between the balloons can be adjusted, e.g. two balloon catheters concentric to each other forming an adjustable multiple balloon catheter system
• CPC Class Codes: A61M 2210/127 Aorta
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters

Abstract

The present invention provides methods, systems and devices for performing cardipulmonary bypass (CPB), cardioplegic arrest, suction of fluid from the aorta to remove embolic or other fluid from the general circulation and the selective segmentation of the arterial system to perform differential perfusion eliminating hypoperfusion. An aortic catheter having an arch lumen which extends at least in part along the length of the catheter shaft has a proximal opening coupled to a CPB machine and a distal arch opening. A corporeal lumen extends at least in part along the length of the catheter shaft and has a proximal opening coupled to a CPB machine and a distal corporeal opening. A suction lumen extends at least in part along the length of the catheter shaft and has a proximal suction opening coupled to a suction source and a distal suction opening residing in the aortic lumen of a patient.

Claims

1. An aortic catheter comprising:

a catheter shaft having an outer tubular member and an inner tubular member, said inner tubular member slidably disposed within said outer tubular member;

an occlusion member expandable from said catheter shaft;

an arch lumen defined by an annular space between said inner and outer tubular members extending at lest in part along the length of said catheter shaft and having at least one distal arch opening, a proximal arch lumen connector in fluid communication with said arch lumen and configured for connection to a CPB machine;

a corporeal lumen having at least one distal corporeal opening positioned distal to said occlusion member, a proximal corporeal lumen connector in fluid communication with said corporeal lumen and configured for connection to a CPB machine; and

a suction source in communication with a port in the catheter shaft proximal to said occlusion device.

2. The aortic catheter of claim 1, wherein said at least one distal arch opening is further comprised of one or more distal arch perfusion ports.

3. The aortic catheter of claim 1, wherein said at least one distal corporeal opening is further comprised of one or more distal corporeal perfusion ports.

4. The aortic catheter of claim 1, further comprising an actuating lumen having a proximal opening coupled to an actuating source and a distal opening configured to expand said occlusion member.

5. The aortic catheter of claim 1, wherein said occlusion member is a balloon.

6. The aortic catheter of claim 1, wherein said arch lumen is sized and configured to perfuse fluid at a first temperature, flow rate and chemical composition to the cerebral subcirculation.

7. The aortic catheter of claim 1, wherein said corporeal lumen is sized and configured to perfuse blood at a second temperature, flow rate and chemical composition to the corporeal subcirculation.

8. The aortic catheter of claim 1, wherein said occlusion member is positioned on said outer tubular member.

9. The aortic catheter of claim 1, further comprising a second occlusion member.

10. The aortic catheter of claim 9, wherein said second occlusion member is mounted on said inner tubular member.

11. The aortic catheter of claim 9, wherein said second occlusion member is eccentric.

12. The aortic catheter of claim 1, wherein said catheter shaft is coated with a lubricious material.

13. The aortic catheter of claim 1, wherein said catheter shaft is coated with medicated material.

14. The aortic catheter of claim 1, wherein said catheter shaft is coated with echogenic material.

15. The aortic catheter of claim 1, wherein said inner tubular member is coil reinforced.

16. A system for perfusing a patient'"'"'s aorta comprising:

a CPB machine;

an aortic catheter comprising;

a catheter shaft having an outer tubular member and an inner tubular member configured in a coaxial relationship such that an annular space is created therebetween;

said outer tubular member and said inner tubular member moveable relative to one another;

an occlusion member expandable from said catheter shaft;

an arch lumen defined by said annular space extending at least in part along the length of said catheter shaft and having at least one distal arch opening, a proximal arch lumen connector in fluid communication with said arch lumen and connected to the CPB machine;

a corporeal lumen defined by the internal diameter of said inner tubular member having at least one distal corporeal opening located distal to said occlusion member, a proximal corporeal lumen connector in fluid communication with said corporeal lumen and connected to the CPB machine;

a suction source in communication with a port in the catheter shaft proximal to said occlusion device; and

a venous cannula having an inflow port configured for receiving deoxygenated blood, and a proximal end residing outside the patent configured for communicating said deoxygenated blood to said CPB machine.

17. The system for perfusing a patient'"'"'s aorta of claim 16, further comprising a switch having a first position and a second position and configured for alternating the communication of said arch lumen from said suction source to said oxygenating means.

18. The system for perfusing a patient'"'"'s aorta of claim 16, wherein said occlusion member is a balloon in fluid communication with an actuating lumen for expanding said balloon.

19. The system for perfusing a patient'"'"'s aorta of claim 16, wherein said arch lumen is sized and configured to perfuse fluid at a predetermined temperature, flow rate and chemical composition to the cerebral subcirculation.

20. The system for perfusing a patient'"'"'s aorta of claim 16, wherein said corporeal lumen is sized and configured to perfuse blood at a predetermined temperature, flow rate and chemical composition to the corporeal subcirculation.

21. The system for perfusing a patient'"'"'s aorta of claim 16, further comprising a second occlusion member.

22. The system for perfusing a patient'"'"'s aorta of claim 16, wherein said second occlusion member is mounted on said outer tubular member.