Method of and device for improving the flow of aqueous humor within the eye

• US 6,726,676 B2
• Filed: 01/05/2000
• Issued: 04/27/2004
• Est. Priority Date: 01/05/2000
• Status: Expired due to Term

• Current Assignee: Alcon Incorporated
• Original Assignee: Grieshaber & Company AG Schaffhausen
• Inventors: Grieshaber, Hans R., Stegmann, Robert
• Primary Examiner(s): Casler, Brian L.
• Assistant Examiner(s): WILLIAMS, CATHERINE SERKE
• Application Number:
  US09/478,047
• Publication Number:
  US 20030139729A1
• Time in Patent Office: 1,574 Days
• Field of Search: 604/48, 604/521, 604/93.01, 604/181, 604/187, 604/264, 604/239, 604/523, 604/533-535, 623/23.64
• US Class Current: 604/523
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

A method for improving the draining of aqueous humor in an eye of a living being and a device for widening the Schlemm'"'"'s canal is described wherein a first incision is made in a lamellar section of the sclera to form a first scleral flap which is then folded upwards in the direction of the cornea, thereby creating a recess in the sclera. A second scleral flap is formed by incising a second lamellar section in the area of the recess and lifted upwardly in the direction of the first sclera flap, thereby exposing two opposite openings into the Schlemm'"'"'s canal into which an expanding medium is injected into the Schlemm'"'"'s canal; formation of a slitlike passageway connecting the aqueous humor-permeable Descemet-membrane with the subscleral space is realized by detaching the Descemet-membrane on the area of the Schwalbe'"'"'s line by means of a slight pressure force; and subsequently, the first scleral flap folded back, after severance of the second scleral flap, for placement upon a support surface formed as a consequence of the incision of the second lamellar section. Subsequently, a viscous medium is injected into a subscleral space formed behind the first scleral flap and the first scleral flap is rejoined to the sclera.

Claims

1. A device for improving the draining of aqueous humor in a surgically exposed Schlemm'"'"'s canal in an eye of a living being, comprising a injection unit and an adapter which has a substantially circular arcuate configuration with at least one probe disposed with a proximal end to the adapter, wherein the probe is provided with at least one outlet channel along a longitudinal axis and in fluid communication with an interior space of the adapter and the injection unit, said probe insertable into at least one location of the circular Schlemm'"'"'s canal exposed by surgical sclera incision, for injecting a viscous medium to thereby generate a localized pressure buildup, wherein said probe includes a transition piece integrally formed with the adapter and having a conical configuration for sealing contact with a lumen of the Schlemm'"'"'s canal, said probe is defined by a diameter and an axial length, with the length being sized at least twice the diameter and wherein the probe has a distal end configured for free motion with respect to the disposition and orientation of the longitudinal axis.

2. The device of claim 1, wherein the probe is made of flexible plastic material.

3. The device of claim 1, wherein the probe is made of transparent plastic.

4. The device of claim 1, wherein the probe is a flexible tube from metal.

5. The device of claim 4, wherein the metal is a nickel titanium alloy.

6. The device of claim 1, wherein the probe has a distal end and a proximal end, said probe flaring outwardly from the distal end in the direction of the proximal end.

7. The device of claim 1, wherein the probe has a proximal end and a distal end, and is disposed at the adapter, said probe is configured for free motion at least at the distal end with respect to the longitudinal axis and freely movable with respect to disposition and orientation.

8. The device of claim 1, wherein the probe is configured for free motion along an entire axial extension of the probe and is provided with a plurality of apertures which are spaced from one another in axial direction and fluidly connected with the outlet port.

9. The device of claim 1, wherein the probe has a proximal end and a distal end and includes a transition piece integrally formed with the adapter, said transition piece having a conical configuration or a circular arc shaped configuration for sealing contact with the Schlemm'"'"'s canal.

10. A device for improving the draining of aqueous humor in a surgically exposed Schlemm'"'"'s canal in an eye of a living being, comprising a injection unit and an adapter with at least one probe disposed with a proximal end to the adapter, wherein the probe is provided with at least one outlet channel along a longitudinal axis and in fluid communication with an interior space of the adapter and the injection unit, said probe insertable into at least one location of the circular Schlemm'"'"'s canal exposed by surgical sclera incision, for injecting a viscous medium to thereby generate a localized pressure buildup, wherein said probe includes a transition piece integrally formed with the adapter and having a conical configuration for sealing contact with a lumen of the Schlemm'"'"'s canal, said probe is defined by a diameter and an axial length, with the length being sized at least twice the diameter and wherein the probe has a distal end configured for free motion with respect to the disposition and orientation of the longitudinal axis, wherein the probe is configured as a elongated tube with a cross section selected from one of a circular ring shape or an elliptical shape, said tube having an inner axial bore which forms an outlet port and is in fluid communication with an interior space of the adapter, which has a substantially circular arcuate configuration.

11. The device of claim 10, wherein the probe is provided with more than one axial bore forming outlet ports.

12. A device for improving the draining of aqueous humor in a surgically exposed Schlemm'"'"'s canal in an eye of a living being, comprising a injection unit and an adapter with at least one probe disposed with a proximal end to the adapter, wherein the probe is provided with at least one outlet channel along a longitudinal axis and in fluid communication with an interior space of the adapter and the injection unit, said probe insertable into at least one location of the circular Schlemm'"'"'s canal exposed by surgical sclera incision, for injecting a viscous medium to thereby generate a localized pressure buildup, wherein said probe includes a transition piece integrally formed with the adapter and having a conical configuration for sealing contact with a lumen of the Schlemm'"'"'s canal, said probe is defined by a diameter and an axial length, with the length being sized at least twice the diameter and wherein the probe has a distal end configured for free motion with respect to the disposition and orientation of the longitudinal axis, wherein the probe is configured as a elongated tube with a cross section selected from one of a circular ring shape or an elliptical shape, said tube having an inner axial bore which forms an outlet port and is in fluid communication with an interior space of the adapter, which has a substantially circular arcuate configuration, wherein the interior space of the adapter is dimensioned with a diameter greater than that of the outlet port for accelerated injection of the viscous medium into the Schlemm'"'"'s canal.

13. A device for improving the draining of aqueous humor in a surgically exposed Schlemm'"'"'s canal in an eye of a living being, comprising a injection unit and an adapter with at least one probe disposed with a proximal end to the adapter, wherein the probe is provided with at least one outlet channel along a longitudinal axis and in fluid communication with an interior space of the adapter and the injection unit, said probe insertable into at least one location of the circular Schlemm'"'"'s canal exposed by surgical sclera incision, for injecting a viscous medium to thereby generate a localized pressure buildup, wherein said probe includes a transition piece integrally formed with the adapter and having a conical configuration or an arcuate configuration for sealing contact with a lumen of the Schlemm'"'"'s canal, said probe is defined by a diameter and an axial length, with the length being sized at least twice the diameter and wherein the probe has a distal end configured for free motion with respect to the disposition and orientation of the longitudinal axis, wherein the probe has a distal end and a proximal end, said probe flaring outwardly from the distal end in the direction of the proximal end.