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Apparatus and methods for preventing or treating failure of hemodialysis vascular access and other vascular grafts

  • US 6,726,923 B2
  • Filed: 01/16/2002
  • Issued: 04/27/2004
  • Est. Priority Date: 01/16/2001
  • Status: Expired due to Term
First Claim
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1. A method of prophylactically treating vasculoproliferative disease in a vascular structure following the construction of an arterio-venous graft, an arterial-arterial graft or an arterio-venous fistula, the method comprising applying locally and external to the vascular structure, perivascularly, a therapeutic agent-eluting sleeve, the sleeve comprising a biocompatible matrix material imbibed with rapamycin thereby enabling delivery of an antiproliferative effective amount of rapamnycin to the vascular structure.

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