Antisense modulation of PTPN12 expression
First Claim
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1. A compound 20 to 80 nucleobases in length targeted to nucleobases 1771 through 1790 of a coding region of a nucleic acid molecule encoding human PTPN12 (SEQ ID NO:
- 4), wherein said compound comprises at least one modified internucleoside linkage, sugar moiety or nucleobase and specifically hybridizes with said region and inhibits the expression of human PTPN12.
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Abstract
Antisense compounds, compositions and methods are provided for modulating the expression of PTPN12. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTPN12. Methods of using these compounds for modulation of PTPN12 expression and for treatment of diseases associated with expression of PTPN12 are provided.
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12 Claims
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1. A compound 20 to 80 nucleobases in length targeted to nucleobases 1771 through 1790 of a coding region of a nucleic acid molecule encoding human PTPN12 (SEQ ID NO:
- 4), wherein said compound comprises at least one modified internucleoside linkage, sugar moiety or nucleobase and specifically hybridizes with said region and inhibits the expression of human PTPN12.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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