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Production of membrane proteins in the milk of transgenic mammals

  • US 6,743,966 B2
  • Filed: 06/27/2002
  • Issued: 06/01/2004
  • Est. Priority Date: 10/02/1991
  • Status: Expired due to Fees
First Claim
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1. A transgenic non-human mammal which contains within its genome a DNA sequence comprising, as operably linked components, a DNA sequence encoding a membrane protein and a mammary gland specific promoter sequence, wherein, upon expression of the DNA sequence, the membrane protein inserts into an apical membrane of a mammary epithelial cell of the mammal, thereby producing the membrane protein in the milk of the mammal.

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