Human semaphorin homologs and polynucleotides encoding the same

• US 6,750,054 B2
• Filed: 05/14/2001
• Issued: 06/15/2004
• Est. Priority Date: 05/18/2000
• Status: Expired due to Fees

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Wang, Xiaoming, Scoville, John, Walke, D. Wade, Turner, C. Alexander Jr.
• Primary Examiner(s): Kunz, Gary
• Assistant Examiner(s): Gucker, Stephen
• Application Number:
  US09/854,845
• Publication Number:
  US 20020098491A1
• Time in Patent Office: 1,128 Days
• Field of Search: 435/320.1, 435/325, 536/23.5
• US Class Current: 435/320.1
• CPC Class Codes: C07K 14/4703 Inhibitors; Suppressors

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic application.

Claims

1. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

4.

5. The isolated nucleic acid molecule of claim 1, wherein said nucleic acid molecule has the sequence of SEQ ID NO:

3.

2. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

2.

6. The isolated nucleic acid molecule of claim 2, wherein said nucleic acid molecule has the sequence of SEQ ID NO:

1.

3. An expression vector comprising a nucleic acid sequence that encodes the amino acid sequence of SEQ ID NO:

4.

4. A host cell comprising the expression vector of claim 3.

7. The expression vector or claim 3, wherein said nucleic acid sequence is that shown in SEQ ID NO:

3.

8. The host cell of claim 4, wherein said expression vector comprises the nucleic acid sequence of SEQ ID NO:

3.

9. An expression vector comprising a nucleic acid sequence that encodes the amino acid sequence of SEQ ID NO:

2.

10. The expression vector of claim 9, wherein said nucleic acid sequence is that shown in SEQ ID NO:

1.

11. A host cell comprising the expression vector of claim 9.

12. The host cell of claim 11, wherein the expression vector comprises the nucleic acid sequence of SEQ ID NO:

1.