Apparatus and method for non-invasive, passive fetal heart monitoring

• US 6,751,498 B1
• Filed: 03/10/2000
• Issued: 06/15/2004
• Est. Priority Date: 03/15/1999
• Status: Expired due to Term

• Current Assignee: Johns Hopkins University
• Original Assignee: Johns Hopkins University
• Inventors: Sternberger, Wayne I., Moses, Edward J., Christion, John A., Greenberg, Robert S.
• Primary Examiner(s): Bockelman, Mark
• Application Number:
  US09/522,664
• Time in Patent Office: 1,558 Days
• Field of Search: 600/511
• US Class Current: 600/511
• CPC Class Codes: A61B 5/02405 Determining heart rate variability
• CPC Class Codes: A61B 5/02411 of foetuses
• CPC Class Codes: A61B 5/282 Holders for multiple electrodes for introduction into the body A61B5/287
• CPC Class Codes: A61B 5/30 Input circuits therefor
• CPC Class Codes: A61B 5/308 for electrocardiography [ECG]
• CPC Class Codes: A61B 5/313 for electromyography [EMG]
• CPC Class Codes: A61B 5/344 Foetal cardiography
• CPC Class Codes: A61B 5/4362 Assessing foetal parameters

Abstract

An apparatus and method for fetal heart and maternal heart and uterine monitoring is provided which acquire biopotential waveforms indicative of the mother'"'"'s heart beat from sensors located at or near the mother'"'"'s chest, and waveforms indicative of the combined maternal and fetal heart beats from abdominal sensors located on the mother'"'"'s abdomen, lower back, or both. The signals from the abdominal sensors are divided into a plurality of channels. An adaptive signal processing filter (ASPF) algorithm or other suitable algorithm is then used to cancel the estimated maternal waveform from each channel derived from the abdominal sensors. The system then selects from the resulting waveforms at least one waveform to serve as the reference fetal waveform. The reference waveform is then processed against the other abdominal waveforms preferably using the ASPF algorithm again to form an enhanced fetal signal that is a representation of the fetus'"'"'s biopotential electrocardiogram (EKG_f). The EKG_f can subsequently be used to measure fetal heart rate and other biophysical profile parameters. Surface electromyogram (EMG) signals allow for concurrent monitoring of uterine contractions and afford improved cancellation of motion artifacts.

Claims

1. A method of monitoring the fetal electrocardiographic waveform of a fetus in a pregnant mother, said method comprising:

measuring at least one biopotential waveform indicative of the maternal heart beat, said maternal biopotential waveform being acquired from at least one sensor located external to the mother at or near the mother'"'"'s chest, to form a maternal waveform;

measuring at least one biopotential waveform indicative of the combined maternal and fetal heart signals to form a combined biopotential waveform, said combined waveform comprising a plurality of signals from sensors located at or near the mother'"'"'s abdomen, lower back, or both, said sensors being located external to the mother and irrespective of the fetal position and to avoid blocking a surgical field, and said method further comprising dividing said signals into a plurality of channels, canceling the maternal waveform from each channel to form a plurality of resulting waveforms, and selecting one of the resulting waveforms to indicate a reference fetal waveform;

wherein the selected reference fetal waveform is enhanced using an adaptive signal processing filter to remove correlated noise by processing against the remaining resulting waveforms that were not selected as the reference fetal waveform.

2. The method of claim 1, further comprising comparing the signal strength of the various resulting waveforms and using the detected signal strengths of the resulting waveforms relative to the sensors located at or near the mother'"'"'s abdomen, lower back, or both to infer a heart vector orientation and the position of said fetus.

3. The method of claim 1, wherein said adaptive signal processing filter uses a least mean squares algorithm to dynamically weigh all of said waveforms derived from the at least one sensor at or near the mother'"'"'s chest against each of the waveforms derived from each of said sensors at or near the mother'"'"'s abdomen, lower back, or both.