Surgical ablation probe for forming a circumferential lesion

• US 6,752,805 B2
• Filed: 06/08/2001
• Issued: 06/22/2004
• Est. Priority Date: 06/13/2000
• Status: Expired due to Term

• Current Assignee: Atrionix, Inc. (Johnson & Johnson)
• Original Assignee: Atrionix, Inc. (Johnson & Johnson)
• Inventors: Maguire, Mark A., Ross, Michael R.
• Primary Examiner(s): Gibson, Roy D.
• Assistant Examiner(s): Vrettakos, Peter J
• Application Number:
  US09/877,620
• Publication Number:
  US 20020019627A1
• Time in Patent Office: 1,110 Days
• Field of Search: 606/15, 606/32, 606/40-41, 606/45-48
• US Class Current: 606/41
• CPC Class Codes: A61B 18/08 by means of electrically-heated probes
• CPC Class Codes: A61B 18/1402 Probes for open surgery
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00065 porous
• CPC Class Codes: A61B 2018/00083 low, i.e. electrically insulating
• CPC Class Codes: A61B 2018/00095 high, i.e. heat conducting
• CPC Class Codes: A61B 2018/00136 with polymer
• CPC Class Codes: A61B 2018/00148 with metal
• CPC Class Codes: A61B 2018/00214 Expandable means emitting energy, e.g. by elements carried thereon
• CPC Class Codes: A61B 2018/00238 porous
• CPC Class Codes: A61B 2018/00285 Balloons
• CPC Class Codes: A61B 2018/00351 Heart
• CPC Class Codes: A61B 2018/00369 Heart valves
• CPC Class Codes: A61B 2018/00375 Ostium, e.g. ostium of pulmonary vein or artery
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00678 upper
• CPC Class Codes: A61B 2018/00761 Duration
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00821 measured by a thermocouple
• CPC Class Codes: A61B 2018/00839 : Bioelectrical parameters, e.g. ECG, EEG
• CPC Class Codes: A61B 2018/00886 : Duration
• CPC Class Codes: A61B 2018/0091 : Handpieces of the surgical instrument or device
• CPC Class Codes: A61B 2018/1407 : Loop
• CPC Class Codes: A61B 2018/1472 : for use with liquid electrolyte, e.g. virtual electrodes
• CPC Class Codes: A61N 7/02 : Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

This invention is a circumferential ablation device assembly which is adapted to form a circumferential conduction block in a pulmonary vein. The assembly generally comprises a handheld surgical ablation probe having a rigid shaft for insertion through a patient'"'"'s chest and a circumferential ablation element mounted on the distal end portion of the shaft. The circumferential ablation element is adapted to ablate a circumferential region of tissue along a pulmonary vein wall which circumscribes the pulmonary vein lumen. The circumferential ablation element includes an expandable member for anchoring the distal end portion of the shaft in a body structure and an ultrasound transducer disposed within the expandable member for emitting ultrasonic energy to ablate the tissue in the pulmonary vein.

Claims

1. A surgical ablation probe for ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium, comprising:

a rigid shaft configured for insertion through an opening in a patient'"'"'s chest, the rigid shaft having proximal and distal end portions and a longitudinal axis, wherein said distal end portion has a preset angle relative to said longitudinal axis of said shaft;

a handle coupled to said proximal end portion of said shaft for manipulating said surgical ablation probe; and

a circumferential ablation member mounted on said distal end portion and adapted for ablating said circumferential region of tissue, wherein said preset angle in said distal end portion of said shaft is adapted to facilitate placement of said circumferential ablation member at said location.

2. The surgical ablation probe of claim 1, wherein said distal end portion of said shaft is deflectable, such that deflection of said distal end portion changes said angle.

3. The surgical ablation probe of claim 2, further comprising a deflection mechanism with a deflection actuator disposed on said handle.

4. The surgical ablation probe of claim 3, wherein said deflection mechanism comprises a pull wire having proximal and distal ends, said proximal end of said pull wire coupled to said deflection actuator and said distal end of said pull wire coupled to said distal end portion of said shaft.

5. The surgical ablation probe of claim 1, further comprising an anchoring member located along said distal end portion of said shaft for releasably anchoring said circumferential ablation member at said location.

6. The surgical ablation probe of claim 5, wherein said anchoring member comprises an expandable member.

7. The surgical ablation probe of claim 6, further comprising an expansion actuator in fluid communication with said expandable member and a pressurized fluid source, wherein actuation of said expansion actuator causes pressurized fluid to radially expand said expandable member.

8. The surgical ablation probe of claim 6, wherein said expandable member comprises an inflatable balloon.

9. The surgical ablation probe of claim 1, wherein said ablation member comprises a cylindrical ultrasound transducer coaxially disposed over said distal end portion of said shaft.

10. The surgical ablation probe of claim 9, wherein said ultrasound transducer has an inner wall and an inner diameter which is greater than an outer diameter of said shaft, such that an air gap is provided in a radial separation between said inner wall of said ultrasound transducer and said shaft.

11. The surgical ablation probe of claim 10, further comprising a support structure coupled to said ultrasound transducer and said shaft so as to maintain said radial separation therebetween.

12. The surgical ablation probe of claim 1, wherein said circumferential ablation member further comprises a circumferential band adapted to ablatively couple to said circumferential region of tissue.

13. The surgical ablation probe of claim 12, wherein said circumferential band comprises at least one ablation electrode electrically coupled to an electrical current source.

14. The surgical ablation probe of claim 1, further comprising a radiopaque marker disposed along said shaft.

15. The surgical ablation probe of claim 1, further comprising a thermocouple positionable along said circumferential region of tissue for providing temperature feedback.

16. The surgical ablation probe of claim 1, further comprising a biocompatible outer extrusion on an outer surface of said shaft.

17. A surgical ablation probe for ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium, comprising:

a substantially rigid shaft configured for insertion through an opening in a patient'"'"'s chest, the substantially rigid shaft having proximal and distal end portions and a longitudinal axis, wherein said distal end portion has an angle relative to said longitudinal axis of said shaft and said distal end portion of said shaft is deflectable by manipulation of a pull-wire system, such that deflection of said distal end portion changes said angle;

a handle coupled to said proximal end portion of said shaft for manipulating said surgical ablation probe;

a cylindrical ultrasound transducer coaxially disposed over said distal end portion of said shaft and adapted for ablating said circumferential region of tissue, wherein said angle in said distal end portion of said shaft is adapted to facilitate placement of said ultrasound transducer at said location; and

an anchoring member located along said distal end portion of said shaft for releasably anchoring said ultrasound transducer at said location.

18. A surgical ablation probe for ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium, comprising:

a substantially rigid shaft configured for insertion through an opening in a patient'"'"'s chest, the substantially rigid shaft having proximal and distal end portions and a longitudinal axis, wherein said distal end portion has an angle relative to said longitudinal axis of said shaft;

a handle coupled to said proximal end portion of said shaft for manipulating said surgical ablation probe; and

a circumferential ablation member mounted on said distal end portion and adapted for ablating said circumferential region of tissue, the circumferential ablation member including an expandable member and one or more ablation elements, the ablation elements being mounted on the outer surface of the expandable member.

19. A surgical ablation probe for ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium, comprising:

a substantially rigid shaft configured for insertion through an opening in a patient'"'"'s chest, the substantially rigid shaft having proximal and distal end portions and a longitudinal axis, wherein said distal end portion has an angle relative to said longitudinal axis of said shaft;

a handle coupled to said proximal end portion of said shaft for manipulating said surgical ablation probe; and

a circumferential ablation member mounted on said distal end portion and adapted for ablating said circumferential region of tissue, the circumferential ablation member including an expandable member and an ablation element, the ablation element being mounted on the substantially rigid shaft inside the expandable member.

20. A surgical ablation probe for ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium, comprising:

a shaft configured for insertion through an opening in a patient'"'"'s chest, the shaft including a substantially rigid proximal end portion having a longitudinal axis and a deflectable distal end portion, wherein said distal end portion is deflectable by manipulation of a pull-wire system to deflect the distal end portion at an angle relative to said longitudinal axis of the proximal end portion;

a handle coupled to said proximal end portion of said shaft for manipulating said surgical ablation probe;

a circumferential ablation member mounted on said distal end portion and adapted for ablating said circumferential region of tissue, wherein said angle of said distal end portion of said shaft is adapted to facilitate placement of said circumferential ablation member at said location.

21. A surgical ablation probe for ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium, comprising:

a substantially rigid shaft configured for insertion through an opening in a patient'"'"'s chest, the substantially rigid shaft having proximal and distal end portions and a longitudinal axis, wherein said distal end portion has an angle relative to said longitudinal axis of said shaft;

a handle coupled to said proximal end portion of said shaft for manipulating said surgical ablation probe; and

a circumferential ablation member mounted on said distal end portion and adapted for ablating said circumferential region of tissue, wherein said angle in said distal end portion of said shaft is adapted to facilitate placement of said circumferential ablation member at said location, said ablation member comprising a cylindrical ultrasound transducer coaxially disposed over said distal end portion of said shaft, wherein said ultrasound transducer has an inner wall and an inner diameter which is greater than an outer diameter of said shaft, such that an air gap is provided in a radial separation between said inner wall of said ultrasound transducer and said shaft.

22. The surgical ablation probe of claim 21, further comprising a support structure coupled to said ultrasound transducer and said shaft so as to maintain said radial separation therebetween.