Membrane material for automated dialysis system

• US 6,764,761 B2
• Filed: 05/24/2002
• Issued: 07/20/2004
• Est. Priority Date: 05/24/2002
• Status: Expired due to Fees

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter International Inc.
• Inventors: Yang, Tahua, Shang, Sherwin, Ling, Michael T. K., Lundtveit, Loren M., Eu, Bruce Ming-Da
• Primary Examiner(s): KIM, SUN U
• Application Number:
  US10/155,954
• Publication Number:
  US 20030217964A1
• Time in Patent Office: 788 Days
• Field of Search: 428/347, 428/349, 428/523, 525/240, 525/241, 525/95, 525/96, 525/97, 525/98, 525/99, 210/232
• US Class Current: 428/349
• CPC Class Codes: A61M 1/153 the cassette being adapted for heating or cooling the treating fluid, e.g. the dialysate or the treating gas
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/159 specially adapted for peritoneal dialysis
• CPC Class Codes: A61M 1/166 Heating for sterilisation A61M1/1686
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/288 Priming priming in extracorporeal blood circuits A61M1/3643
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: B32B 27/08 of synthetic resin
• CPC Class Codes: Y10T 428/2817 Heat sealable
• CPC Class Codes: Y10T 428/2826 Synthetic resin or polymer
• CPC Class Codes: Y10T 428/31938 Polymer of monoethylenically unsaturated hydrocarbon

Abstract

A method, system and apparatus for performing peritoneal dialysis are provided. To this end, in part, a film is provided. The film includes a layer of a polymer blend having from about 90% to about 99% by weight of a first component containing a styrene and hydrocarbon copolymer and from about 10% to about 1% of a high melt strength polypropylene.

Claims

1. A film comprising:

a layer of a polymer blend comprising from about 90% to about 99% by weight of a first component containing a styrene and hydrocarbon copolymer and from about 10% to about 1% by weight of a high melt strength polypropylene having a melt flow index in the range of 10 grams/10 minutes to 800 grams/10 minutes.

2. The film of claim 1 wherein the styrene and hydrocarbon copolymer is a styrene-ethylene-butylene-styrene block copolymer.

3. The film of claim 2 wherein the first component contains 5-40% by weight of an oil.

4. The film of claim 1 wherein the high melt strength polypropylene has free end long chain branching.

5. The film of claim 1 wherein the high melt strength polypropylene is obtained by reacting a polypropylene with an organic peroxide.

6. The film of claim 5 wherein the high melt strength polypropylene is obtained by kneading the polypropylene after reacting with the organic peroxide.

7. The film of claim 1 having a modulus of elasticity of less than about 10,000 psi when measured in accordance with ASTM D882.

8. The film of claim 1 having a modulus of elasticity of less than about 5,000 psi when measured in accordance with ASTM D882.

9. The film of claim 1 having a thermal conductivity of greater than 0.13 W/meter-°

K.

10. The film of claim 1 wherein the film is capable of being extruded at a rate greater than 50 ft/min.

11. The film of claim 1 wherein the film is a monolayer structure.

12. The film of claim 1 wherein the film is a multiple layer structure and the layer defines a seal layer of the film.

33. The film of claim 1 wherein the high melt strength polypropylene is obtained by irradiating a linear propylene polymer with high energy ionization energy.

13. A cassette and membrane assembly comprising:

a cassette comprising a first polymer blend comprising from about 70% to about 95 by weight of a first polyolefin and from about 5% to about 30% by weight of a first styrene and hydrocarbon copolymer; and

a film attached to the cassette comprising a layer of a second polymer blend of from about 90% to about 99% by weight of a first component containing a second styrene and hydrocarbon copolymer and from about 10% to about 1% by weight of a high melt strength polypropylene having a melt flow index within the range of 10 grams/10 minutes to 800 grams/10 minutes.

14. The assembly of claim 13 wherein the first polyolefin is selected from the group consisting of a first polypropylene homopolymer and a first polypropylene copolymer.

15. The assembly of claim 14 wherein the first polypropylene copolymer is a copolymer of propylene with an α

-olefin having from 2 to 20 carbons.

16. The assembly of claim 14 wherein the first styrene and hydrocarbon copolymer is a block copolymer selected from the group consisting of di-block, tri-block, multiblock, and star block copolymers.

17. The assembly of claim 14 wherein the first styrene and hydrocarbon copolymer is a first styrene-ethylene-butylene-styrene block copolymer.

18. The assembly of claim 13 wherein the second styrene and hydrocarbon copolymer is a block copolymer selected from the group consisting of di-block, tri-block, multiblock, and star block copolymers.

19. The assembly of claim 18 wherein the second styrene and hydrocarbon copolymer is a second styrene-ethylene-butylene-styrene block copolymer.

20. The assembly of claim 19 wherein the first component contains from about 5-40% by weight of an oil.

21. The assembly of claim 13 wherein the high melt strength polypropylene has free end long chain branching.

22. The assembly of claim 13 wherein the high melt strength polypropylene is obtained by reacting a polypropylene with an organic peroxide.

23. The assembly of claim 22 wherein the high melt strength polypropylene is obtained by kneading the polypropylene after reacting with the organic peroxide.

24. The assembly of claim 13 wherein the film has a modulus of elasticity of less than about 10,000 psi when measured in accordance with ASTM D882.

25. The assembly of claim 13 wherein the film has a modulus of elasticity of less than about 5,000 psi when measured in accordance with ASTM D882.

26. The assembly of claim 13 wherein the film has a thermal conductivity of greater than 0.13 W/meter-°

K.

27. The assembly of claim 13 wherein the film is capable of being extruded at a rate greater than 50 ft/min.

28. The assembly of claim 13 wherein the film is a monolayer structure.

29. The assembly of claim 13 wherein the film is a multiple layer structure and the layer defines a seal layer of the film.

30. The assembly of claim 13 wherein the film can be deformed under a pressure of 5 psi.

31. The assembly of claim 13 wherein the film has a peel strength from the cassette of greater than about 5 lbf/in.

32. The assembly of claim 14 wherein the first polypropylene has a melting point temperature of from about 120°

C. to about 140°

C. and the high melt strength polypropylene has a melting point temperature of from about 145°

C. to about 160°

C.