Systems and methods for intradermal collagen stimulation

• US 6,766,202 B2
• Filed: 04/30/2002
• Issued: 07/20/2004
• Est. Priority Date: 08/30/1999
• Status: Expired due to Fees

• Current Assignee: ArthroCare Corporation (Smith & Nephew PLC)
• Original Assignee: ArthroCare Corporation (Smith & Nephew PLC)
• Inventors: Woloszko, Jean, Underwood, Ronald A.
• Primary Examiner(s): COHEN, LEE S
• Application Number:
  US10/135,478
• Publication Number:
  US 20020128641A1
• Time in Patent Office: 812 Days
• Field of Search: 606/32, 606/41, 607/99, 607/105, 607/113, 128/898
• US Class Current: 607/99
• CPC Class Codes: A61B 18/14 Probes or electrodes therefor
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 2018/00452 Skin
• CPC Class Codes: A61B 2018/1425 Needle
• CPC Class Codes: A61B 2018/1472 for use with liquid electrolyte, e.g. virtual electrodes
• CPC Class Codes: A61B 2218/002 Irrigation

Abstract

The present invention provides systems, apparatus and methods for selective applying energy to a patient'"'"'s dermis tissue to generate the growth of new collagen in this tissue, while minimizing the effect on the outer epidermis layer, thereby minimizing or suppressing the wound healing phase of the procedure. In one aspect of the invention, a method includes positioning a first electrode adjacent to, or in contact with, a region on or within a patient'"'"'s skin, and applying a sufficient high frequency voltage between the first electrode and a second electrode to create a heat injury to a target tissue within the patient'"'"'s dermis layer without ablating the epidermis layer overlying the target tissue. Typically, the voltage applied to the first and second electrodes is sufficient to induce heating of the dermis layer to about 60°-80° C., preferably about 65°-75° C. This induced heating causes the patient'"'"'s body to undergo a wound healing response in the slightly inflamed tissue of the dermis. The wound healing process involves the generation of neo-collagen in the dermis layer, which fills in the wrinkle in the patient'"'"'s skin.

Claims

1. A method for treating wrinkles in a patient'"'"'s skin comprising:

positioning first and second electrodes adjacent to, or in contact with, an outer surface of the patient'"'"'s skin, where the electrodes are placed on either side of a wrinkle; and

applying a sufficient high frequency voltage difference between the first and second electrodes such that electric current flows from the first electrode through target tissue in the patient'"'"'s dermis layer to the second electrode without ablating the epidermis layer overlying the target tissue wherein the applying act comprises translating the electrodes alone the length of the wrinkle.

2. The method of claim 1 further comprising spacing the first and second electrodes a distance sufficient to cause the electric current to pass through the epidermis into the target tissue in the dermis layer.

3. The method of claim 1 further comprising spacing the first and second electrodes about 5 to 20 cm from each other.

4. The method of claim 1 further comprising minimizing current density in the epidermis during the applying step.

5. The method of claim 1 wherein the minimizing step is carried out by selecting electrode shapes that provide a homogenous current distribution around the electrodes.

6. The method of claim 1 wherein the first and second electrodes comprise rounded shapes with substantially no edges.

7. A method for treating wrinkles in a patient'"'"'s skin comprising:

positioning first and second electrodes adjacent to, or in contact with, an outer surface of the patient'"'"'s skin, where the electrodes are placed on either side of a wrinkle; and

applying a sufficient high frequency voltage difference between the first and second electrodes such that electric current flows from the first electrode through target tissue in the patient'"'"'s dermis layer to the second electrode without ablating the epidermis layer overlying the target tissue and wherein the method further comprising coating the electrode surfaces with an electrically conductive hydrogel and soaking the hydrogel with an electrically conductive liquid.

8. A system for treating wrinkles in a patient'"'"'s skin comprising:

an electrosurgical instrument having a shaft with a proximal end portion, a distal end portion and a first electrode on the distal end portion;

a second electrode, where the first and second electrodes are adapted to be placed on a first side and a second side of a wrinkle;

a power supply for applying a high frequency voltage difference between the first and second electrodes; and

wherein the electrodes are configured such that, when the first and second electrodes are spaced from each other adjacent to, or in contact with, an outer surface of a patient'"'"'s skin and a sufficient high frequency voltage difference is applied therebetween, electric current passes from the first electrode through target tissue in the patient'"'"'s dermis to the second electrode without ablating the epidermis layer overlying the target tissue and wherein the first and second electrodes comprise electrically conductive hydrogel located at the surfaces of the first and second electrodes and wherein the hydro gel is soaked with an electrically conductive liquid.

9. The system of claim 8 wherein the second electrode is coupled to the electrosurgical instrument such that the first and second electrodes are spaced from each other by a distance of about 5 to 20 cm.

10. The system of claim 8 wherein the second electrode is coupled to the electrosurgical instrument such that the first and second electrodes are axially spaced a substantially equivalent distance from the instrument shaft.

11. The system of claim 8 wherein the first and second electrodes comprise rounded shapes with substantially no edges.

12. A system for treating wrinkles in a patient'"'"'s skin comprising:

an electrosurgical instrument having a shaft with a proximal end portion, a distal end portion and a first electrode on the distal end portion;

a second electrode, where the first and second electrodes are adapted to be placed on a first side and a second side of a wrinkle;

a power supply for applying a high frequency voltage difference between the first and second electrodes; and

wherein the electrodes are configured such that, when the first and second electrodes are spaced from each other adjacent to, or in contact with, an outer surface of a patient'"'"'s skin and a sufficient high frequency voltage difference is applied therebetween, electric current passes from the first electrode through target tissue in the patient'"'"'s dermis to the second electrode without ablating the epidermis layer overlying the target tissue wherein the first and second electrodes comprise a spherical or hemispherical shape.

13. A method for treating wrinkles in a patient'"'"'s skin comprising:

positioning a first electrode and a second electrodes adjacent to, or in contact with, an outer surface of the patient'"'"'s skin;

coating a surface of the first and second electrodes with an electrically conductive hydrogel and soaking the hydrogel with an electrically conductive liquid; and

applying a sufficient high frequency voltage difference between the first and second electrodes such that electric current flows from the first electrode through target tissue in the patient'"'"'s dermis layer to the second electrode without ablating the epidermis layer overlying the target tissue.

14. A system for treating wrinkles in a patient'"'"'s skin comprising:

an electrosurgical instrument having a shaft with a proximal end portion, a distal end portion and a first electrode on the distal end portion;

a second electrode, wherein the first and second electrodes comprise a spherical or hemispherical shape;

a power supply for applying a high frequency voltage difference between the first and second electrodes; and

wherein the electrodes are configured such that, when the first and second electrodes are spaced from each other adjacent to, or in contact with, an outer surface of a patient'"'"'s skin and a sufficient high frequency voltage difference is applied therebetween, electric current passes from the first electrode through target tissue in the patient'"'"'s dermis to the second electrode without ablating the epidermis layer overlying the target tissue.

15. A system for treating wrinkles in a patient'"'"'s skin comprising:

an electrosurgical instrument having a shaft with a proximal end portion, a distal end portion and a first electrode on the distal end portion;

a second electrode, where the first and second electrodes are adapted to be placed on opposite sides of a wrinkle;

an electrically conductive hydrogel coated on the surfaces of the first and second electrodes, wherein the hydrogel is soaked with an electrically conductive liquid;

a power supply for applying a high frequency voltage difference between the first and second electrodes; and

wherein the electrodes are configured such that, when the first and second electrodes are spaced from each other adjacent to, or in contact with, an outer surface of a patient'"'"'s skin and a sufficient high frequency voltage difference is applied therebetween, electric current passes from the first electrode through target tissue in the patient'"'"'s dermis to the second electrode without ablating the epidermis layer overlying the target tissue.