Contrast agent comprising low density microspheres
First Claim
1. A contrast agent comprising an aqueous suspension of low density microspheres, said low density microspheres having a void containing a gas or the vapor of a volatile liquid selected from the group consisting of aliphatic hydrocarbons, chlorofluorocarbons, tetraalkyl silanes and perfluorocarbons, wherein said void has a volume that comprises at least about 75% of the volume of the microsphere and wherein said contrast agent is suitable for administration to a patient either orally, rectally, or by injection.
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Abstract
Low density microspheres, methods for preparing same, and use of same as contrast agents are described. The microspheres have a void having a volume that comprises at least about 75% of the total volume of the microspheres, and which contains a gas or the vapor of a volatile liquid selected from the group consisting of aliphatic hydrocarbons, chlorofluorocarbons, tetraalkyl silanes and perfluorocarbons.
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Citations
14 Claims
- 1. A contrast agent comprising an aqueous suspension of low density microspheres, said low density microspheres having a void containing a gas or the vapor of a volatile liquid selected from the group consisting of aliphatic hydrocarbons, chlorofluorocarbons, tetraalkyl silanes and perfluorocarbons, wherein said void has a volume that comprises at least about 75% of the volume of the microsphere and wherein said contrast agent is suitable for administration to a patient either orally, rectally, or by injection.
Specification