Microbial transformation method for the preparation of an epothilone
First Claim
Patent Images
1. A method for the preparation of at least one hydroxyalkyl-bearing compound of the following formula III:
- whereQ is selected from the group consisting of G1 is the following formula V
1 Assignment
0 Petitions
Accused Products
Abstract
A microbial method for the preparation of an epothilone containing a terminal hydroxyalkyl group, comprising contacting at least one epothilone having a terminal alkyl group with an enzyme or microorganism capable of catalyzing the selective hydroxylation of said alkyl group to a hydroxyalkyl group, and effecting said hydroxylation.
-
Citations
21 Claims
-
1. A method for the preparation of at least one hydroxyalkyl-bearing compound of the following formula III:
-
where Q is selected from the group consisting of G1 is the following formula V - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
-
Specification