Polynucleotides encoding human ion-exchanger proteins

• US 6,787,352 B2
• Filed: 09/24/2001
• Issued: 09/07/2004
• Est. Priority Date: 09/27/2000
• Status: Expired due to Fees

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Friddle, Carl Johan, Gerhardt, Brenda
• Primary Examiner(s): Kunz, Gary
• Assistant Examiner(s): Li, Ruixiang
• Application Number:
  US09/961,679
• Publication Number:
  US 20020107380A1
• Time in Patent Office: 1,079 Days
• Field of Search: 536/23.5, 536/23.1, 530/350, 435/320.1, 435/325, 435/252.3, 435/254.11, 435/254.2
• US Class Current: 435/325
• CPC Class Codes: A61K 38/00 Medicinal preparations containing peptides peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00
• CPC Class Codes: C07K 14/705 Receptors; Cell surface antigens; Cell surface determinants tumour specific antigens C07K14/4748

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated nucleic acid molecule comprising a nucleotide sequence encoding an amino acid sequence drawn from the group consisting of SEQ ID NOS:

2, 4, and 6.

6. A recombinant expression vector comprising an isolated nucleic acid molecule of claim 1.

7. A host cell comprising the recombinant expression vector of claim 6.

2. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

2; and

(b) hybridizes to the nucleotide sequence of SEQ ID NO;

1 or the complement thereof.

3. An isolated nucleic acid molecule comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

2.

4. An isolated nucleic acid molecule comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

4.

5. An isolated nucleic acid molecule comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

6.