Microfluidic channels with integrated ultrasonic transducers for temperature measurement and method

• US 6,789,426 B2
• Filed: 07/17/2002
• Issued: 09/14/2004
• Est. Priority Date: 07/31/2001
• Status: Expired due to Fees

• Current Assignee: Board of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
• Original Assignee: Board of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
• Inventors: Khuri-Yakub, Butrus T., Yaralioglu, Goksen G., Jagannathan, Hemanth, Ergun, Arif S.
• Primary Examiner(s): CHAPMAN JR, JOHN E
• Application Number:
  US10/198,290
• Publication Number:
  US 20030029242A1
• Time in Patent Office: 790 Days
• Field of Search: 735/97, 736/22, 374/119, 374/117
• US Class Current: 73/597
• CPC Class Codes: G01H 5/00 Measuring propagation velocity of ultrasonic, sonic or infrasonic waves , e.g. of pressure waves
• CPC Class Codes: G01K 11/24 of the velocity of propagation of sound
• CPC Class Codes: G01N 2291/02881 Temperature
• CPC Class Codes: G01N 29/024 by measuring propagation velocity or propagation time of acoustic waves
• CPC Class Codes: G01N 29/223 Supports, positioning or alignment in fixed situation mounting transducers per se G10K11/004
• CPC Class Codes: G01N 29/326 compensating for temperature variations

Abstract

There is described a method and apparatus for measuring temperature of a fluid in a microchannel of the type having spaced walls. An ultrasonic transducer transmits ultrasonic waves transmitted from one wall to the opposite wall. A processor determines the time-of-flight of the ultrasonic waves from the one wall and reflected to the opposite wall to the one wall. The processor converts the time-of-flight to velocity by dividing the distance between walls by the time-of-flight. The processor converts velocity to temperature from the relationship of velocity to temperature in the fluid.

Claims

1. A sensor for sensing velocity of ultrasonic waves in fluids in microchannels formed in a microfluidic device comprising:

a capacitive micromachined ultrasonic transducer integrated in one wall of the channel,

a pulser for applying electrical pulses to said ultrasonic transducer to transmit ultrasonic waves which travel through the fluid in said channel and reflect from the opposite wall of said channel, said transducer adapted to receive ultrasonic waves reflected from the opposite wall and generate an output signal,

an analog to digital converter connected to received said output signals and provide a representative digital output, and

a processor configured to receive said digital output and determine the time of travel of ultrasonic waves through the fluid and to determine from the time of travel and the distance the ultrasonic waves travel through the fluid the velocity of the ultrasonic waves in the fluid.

2. A sensor as in claim 1 in which the processor includes a look-up table showing the velocity of the fluid as a function of temperature whereby the processor compares the velocity of the ultrasonic waves in the fluid to the look-up table to provide an output representative of temperature.

3. A sensor for sensing velocity of sound in fluids in microchannels formed in a microfluidic device comprising:

a capacitive micromachined ultrasonic transducer integrated into one wall of said microchannel;

a pulser for applying electrical pulses to said ultrasonic transducer to transmit ultrasonic waves which travel through the fluid in said channel and reflect from the opposite wall of said channel, said transducer adapted to receive ultrasonic waves and generate an output signal; and

a processor circuit configured to receive the electrical pulses and the output signal and determine the velocity of the ultrasonic waves by measuring the phase difference between the transmitted ultrasonic waves and the received ultrasonic waves.

4. A sensor as in claim 3 in which the processor includes a look-up table showing the velocity of the fluid as a function of temperature whereby the processor compares the velocity of the ultrasonic waves in the fluid to that in the look-up table to provide an output representative of temperature.