Apparatus and method for reducing mitral regurgitation

• US 6,790,231 B2
• Filed: 02/05/2002
• Issued: 09/14/2004
• Est. Priority Date: 02/05/2001
• Status: Expired due to Term

• Current Assignee: Ancora Heart, Inc.
• Original Assignee: Viacor, Inc.
• Inventors: Cohn, William E., Liddicoat, John R., Streeter, Richard B., Woolfson, Steven B.
• Primary Examiner(s): Isabella, David J.
• Assistant Examiner(s): Chattopadhyay, Urmi
• Application Number:
  US10/068,700
• Publication Number:
  US 20020183836A1
• Time in Patent Office: 952 Days
• Field of Search: 623/1, 623/2, 623/900, 623/904, 600/37, 606/108, 606/191-198, 606/139, 128/898
• US Class Current: 623/2.37
• CPC Class Codes: A61F 2/2451 Inserts in the coronary sinus for correcting the valve shape

Abstract

Apparatus for reducing mitral regurgitation, including a bendable elongated body adapted to be inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the elongated body being adjustable between a first configuration adapted to be delivered into the coronary sinus and a second configuration adapted to exert a force onto the posterior annulus. The body includes a flexible spine having a proximal end and a distal end, and a flexible wire mounted on the spine and having a distal end fixed to the spine proximate to the distal end of the spine, and having a proximal portion extending from the proximal end of the spine. Axial movement of the wire causes a change in the spine from the first configuration to the second configuration to exert the force on the posterior annulus and thereby reduce mitral regurgitation.

Claims

1. Apparatus for reducing mitral regurgitation, the apparatus comprising:

a bendable elongated body adapted to be inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the elongated body being adjustable between a first configuration adapted to be delivered into the coronary sinus and a second configuration adapted to exert a force onto the posterior annulus, the body comprising;

a flexible spine having a proximal end and a distal end, said flexible spine forming a longitudinal axis from said proximal end to said distal end, a plurality of wire supporting portions extending transversely from said spine, each said portion defining a channel therethrough, said plurality of wire supporting portions defining a plurality of openings therebetween, and a plurality of flexible bridges connecting said plurality of wire supporting portions to one another; and

a flexible wire slideably mounted through said plurality of wire supporting portions extending from said spine and having a distal end fixed to said spine proximate to the distal end of said spine, and having a proximal portion extending from the proximal end of said spine;

whereby axial movement of said wire causes a change in said spine from the first configuration to the second configuration to exert the force on the posterior annulus and thereby reduce mitral regurgitation.

2. The apparatus in accordance with claim 1, wherein the axial movement of said wire through said plurality of wire supporting portions in a proximal direction causes said spine reconfiguration to a lesser curve having a greater radius of curvature.

3. The apparatus in accordance with claim 1 wherein the axial movement of said wire in a distal direction through said plurality of wire supporting portions causes said spine to reconfigure to a more pronounced curve having a lesser radius of curvature.

4. The apparatus in accordance with claim 1 wherein the first configuration is curved and the second configuration is a selected one of (i) more curved and (ii) less curved.

5. The apparatus in accordance with claim 4 wherein the selected one of the second configuration is the less curved configuration, and further wherein the less curved configuration is substantially straight.

6. The apparatus in accordance with claim 1 wherein said spine is provided with barbs thereon.

7. Apparatus for reducing mitral regurgitation, the apparatus comprising:

a bendable elongated body adapted to be inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the elongated body being adjustable between a first configuration adapted to be delivered into the coronary sinus and a second configuration adapted to exert a force onto the posterior annulus, the body comprising;

a flexible spine having a proximal end and a distal end; and

a flexible wire mounted on said spine and having a distal end fixed to said spine proximate to the distal end of said spine, and having a proximal portion extending from the proximal end of said spine;

whereby pulling of said wire causes straightening of said spine to move said spine from the first configuration to the second configuration to exert the force on the posterior annulus and thereby reduce mitral regurgitation.

8. The apparatus in accordance with claim 7, wherein loops are mounted on said spine and said wire is movable therein.

9. The apparatus in accordance with claim 8, wherein said loops are staples.

10. Apparatus for reducing mitral regurgitation, the apparatus comprising:

a bendable elongated body adapted to be inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the elongated body being adjustable between a first configuration adapted to be delivered into the coronary sinus and a second configuration adapted to exert a force onto the posterior annulus, the body comprising;

a flexible spine having a proximal end and a distal end; and

a flexible wire mounted on said spine and having a distal end fixed to said spine proximate to the distal end of said spine, and having a proximal portion extending from the proximal end of said spine;

whereby axial movement of said wire causes a change in said spine from the first configuration to the second configuration to exert the force on the posterior annulus and thereby reduce mitral regurgitation;

wherein the axial movement of said wire in a proximal direction causes said spine reconfiguration to a lesser curve having a greater radius of curvature.

11. Apparatus for reducing mitral regurgitation, the apparatus comprising:

a bendable elongated body adapted to be inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the elongated body being adjustable between a first configuration adapted to be delivered into the coronary sinus and a second configuration adapted to exert a force onto the posterior annulus, the body comprising;

a flexible spine having a proximal end and a distal end; and

a flexible wire mounted on said spine and having a distal end fixed to said spine proximate to the distal end of said spine, and having a proximal portion extending from the proximal end of said spine;

whereby axial movement of said wire causes a change in said spine from the first configuration to the second configuration to exert the force on the posterior annulus and thereby reduce mitral regurgitation;

wherein the axial movement of said wire in a distal direction causes said spine to reconfigure to a more pronounced curve having a lesser radius of curvature.

12. Apparatus for reducing mitral regurgitation, the apparatus comprising:

a bendable elongated body adapted to be inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the elongated body being adjustable between a first configuration adapted to be delivered into the coronary sinus and a second configuration adapted to exert a force onto the posterior annulus, the body comprising;

a flexible spine having a proximal end and a distal end; and

a flexible wire mounted on said spine and having a distal end fixed to said spine proximate to the distal end of said spine, and having a proximal portion extending from the proximal end of said spine;

whereby axial movement of said wire causes a change in said spine from the first configuration to the second configuration to exert the force on the posterior annulus and thereby reduce mitral regurgitation;

wherein loops are fixed to said spine and said wire extends through said loops and is movable therethrough.

13. Apparatus for reducing mitral regurgitation, the apparatus comprising:

a bendable elongated body adapted to be inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the elongated body being adjustable between a first configuration adapted to be delivered into the coronary sinus and a second configuration adapted to exert a force onto the posterior annulus, the body comprising;

a flexible spine having a proximal end and a distal end; and

a flexible wire mounted on said spine and having a distal end fixed to said spine proximate to the distal end of said spine, and having a proximal portion extending from the proximal end of said spine;

whereby axial movement of said wire causes a change in said spine from the first configuration to the second configuration to exert the force on the posterior annulus and thereby reduce mitral regurgitation;

wherein loops are fixed to said spine and said wire extends through said loops and is movable therethrough; and

wherein the loops are defined by staples.