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Method of preparing an oligonucleotide array

  • US 6,790,613 B1
  • Filed: 11/12/1999
  • Issued: 09/14/2004
  • Est. Priority Date: 11/12/1999
  • Status: Expired due to Fees
First Claim
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1. A method of making an oligonucleotide array comprising:

  • a. providing an array of porous polymer gel pads on the surface of a solid support;

    b. adding an oligonucleotide probe to each of said porous polymer gel pads;

    c. freezing said array of porous polymer gel pads comprising said oligonucleotide probes to produce a frozen array said porous polymer gel pads being hydrated prior to freezing; and

    d. drying said frozen array of porous polymer gel pads by sublimation for a time sufficient to increase the pore size of each of said porous polymer gel pads.

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