Methods and systems for automatically determining minute ventilation

• US 6,795,733 B1
• Filed: 03/21/2002
• Issued: 09/21/2004
• Est. Priority Date: 03/21/2002
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Lu, Richard
• Primary Examiner(s): Layno, Carl
• Application Number:
  US10/103,605
• Time in Patent Office: 915 Days
• Field of Search: 607/17, 600/508, 600/509, 600/513, 600/522, 600/536, 600/547
• US Class Current: 607/17
• CPC Class Codes: A61B 5/0535 Impedance plethysmography for measuring blood flow A61B5/0295
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/0809 by impedance pneumography
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance
• CPC Class Codes: A61N 1/3686 configured for selecting the electrode configuration on a lead A61N1/3688 takes precedence

Abstract

Methods and systems for switching electrode configurations for measuring the transthoracic impedance of patient are described. Various embodiments provide stimulation devices and methods that can automatically adapt to different minute ventilation electrode configurations. This, in turn, permits minute ventilation functionality to continue, e.g. rate-responsive pacing, in spite of the fact that an electrode configuration has changed. Accordingly, minute ventilation functionality can automatically continue in a adaptive manner when a previously-available electrode configuration is no longer available for minute ventilation functionality.

Claims

1. A method for ascertaining minute ventilation comprising:

providing a programmable stimulation device having multiple electrodes; and

programming the stimulation device with code which, when executed by the stimulation device is configured to cause the stimulation device to;

establish a first electrode configuration sufficient for use in ascertaining a patient'"'"'s minute ventilation;

ascertain the patient'"'"'s minute ventilation using the first electrode configuration;

monitor the integrity of the first electrode configuration; and

responsive to a problem with the integrity of the first electrode configuration, switch to a different electrode configuration sufficient for use in ascertaining the patient'"'"'s minute ventilation.

2. The method of claim 1, wherein the first electrode configuration comprises a ventricular bipolar configuration.

3. The method of claim 1, wherein the different electrode configuration comprises one or more of an atrial bipolar configuration and a dual unipolar configuration.

4. The method of claim 1, wherein the first electrode configuration comprises a bipolar configuration and the different electrode configuration comprises a unipolar configuration.

5. The method of claim 1, wherein said monitoring comprises monitoring one or more electrode impedances associated with leads that carry electrodes defining the first electrode configuration.

6. A method for ascertaining minute ventilation comprising:

providing a stimulation device having multiple electrodes; and

configuring the stimulation device to;

establish a first electrode configuration sufficient for use in ascertaining a patient'"'"'s minute ventilation;

ascertain the patient'"'"'s minute ventilation using the first electrode configuration;

monitor the integrity of the first electrode configuration; and

responsive to a problem with the integrity of the first electrode configuration, switch to a different electrode configuration sufficient for use in ascertaining the patient'"'"'s minute ventilation.

7. A stimulation device comprising:

one or more computer-readable media;

one or more processors; and

instructions stored on the computer-readable media which, when executed by the one or more processors, cause the processors to;

establish a first electrode configuration sufficient for use in ascertaining a patient'"'"'s minute ventilation;

ascertain the patient'"'"'s minute ventilation using the first electrode configuration;

monitor the integrity of the first electrode configuration; and

responsive to a problem with the integrity of the first electrode configuration, switch to a different electrode configuration sufficient for use in ascertaining the patient'"'"'s minute ventilation.

8. The stimulation device of claim 7, wherein the first electrode configuration comprises a ventricular bipolar configuration.

9. The stimulation device of claim 7, wherein the different electrode configuration comprises one or more of an atrial bipolar configuration and a dual unipolar configuration.

10. The stimulation device of claim 7, wherein the first electrode configuration comprises a bipolar configuration and the different electrode configuration comprises a unipolar configuration.

11. The stimulation device of claim 7, wherein the instructions cause the one or more processors to monitor the integrity of the first electrode configuration by monitoring one or more electrode impedances associated with leads that carry electrodes defining the first electrode configuration.

12. One or more computer-readable media having computer-readable instructions thereon which, when executed by one or more processors of a stimulation device, cause the one or more processors to:

establish a first electrode configuration sufficient for use in ascertaining a patient'"'"'s minute ventilation;

ascertain the patient'"'"'s minute ventilation using the first electrode configuration;

monitor the integrity of the first electrode configuration; and

responsive to a problem with the integrity of the first electrode configuration, switch to a different electrode configuration sufficient for use in ascertaining the patient'"'"'s minute ventilation.

13. A method for ascertaining minute ventilation comprising:

establishing a first electrode configuration using a stimulation device, the first electrode configuration being sufficient for use in ascertaining a patient'"'"'s minute ventilation;

ascertaining the patient'"'"'s minute ventilation using the first electrode configuration;

monitoring the integrity of the first electrode configuration;

responsive to a problem with the integrity of the first electrode configuration, automatically switching to a different electrode configuration sufficient for use in ascertaining the patient'"'"'s minute ventilation; and

using the different electrode configuration to ascertain the patient'"'"'s minute ventilation.

14. The method of claim 13, wherein said establishing a first electrode configuration comprises establishing a ventricular bipolar configuration.

15. The method of claim 13, wherein said automatically switching to a different electrode configuration comprises automatically switching to one or more of an atrial bipolar configuration and a dual unipolar configuration.

16. The method of claim 13, wherein:

said establishing a first electrode configuration comprises establishing a bipolar configuration; and

said automatically switching to a different electrode configuration comprises automatically switching to a unipolar configuration.

17. A method of ascertaining minute ventilation comprising:

defining priorities between multiple different minute ventilation electrode configurations;

establishing a minute ventilation electrode configuration in accordance with defined priorities;

ascertaining minute ventilation using the established minute ventilation electrode configuration;

monitoring the integrity of the established minute ventilation electrode configuration;

responsive to a problem with the integrity of the established minute ventilation electrode configuration, switching to a lower priority minute ventilation electrode configuration; and

determining minute ventilation using the lower priority minute ventilation electrode configuration.

18. The method of claim 17, wherein the first-established minute ventilation electrode configuration comprises a ventricular bipolar configuration.

19. The method of claim 17, wherein the first-established minute ventilation electrode configuration comprises a atrial bipolar configuration.

20. The method of claim 17, wherein the first-established minute ventilation electrode configuration comprises a dual unipolar configuration.

21. The method of claim 17, wherein the lower priority minute ventilation electrode configuration comprises a atrial bipolar configuration.

22. The method of claim 17, wherein the lower priority minute ventilation electrode configuration comprises a dual unipolar configuration.

23. The method of claim 17, wherein the lower priority minute ventilation electrode configuration comprises a ventricular bipolar configuration.

24. The method of claim 17, wherein said monitoring comprises monitoring impedances associated with leads that carry electrodes defining the established electrode configuration.

25. One or more computer-readable media having computer-readable instructions thereon which, when executed by one or more processors, cause the processors to implement the method of claim 17.

26. A stimulation device comprising:

one or more computer-readable media;

multiple electrodes for stimulating and for monitoring minute ventilation;

one or more processors; and

instructions stored on the computer-readable media which, when executed by the one or more processors, cause the processors to;

define priorities between multiple different minute ventilation electrode configurations;

establish a minute ventilation electrode configuration in accordance with defined priorities;

ascertain minute ventilation using the established minute ventilation electrode configuration;

monitor the integrity of the established minute ventilation electrode configuration;

responsive to a problem with the integrity of the established minute ventilation electrode configuration, switch to a lower priority minute ventilation electrode configuration; and

determine minute ventilation using the lower priority minute ventilation electrode configuration.

27. A method of ascertaining minute ventilation comprising:

detecting a problem associated with an electrode configuration that is being utilized to ascertain minute ventilation for a rate-responsively paced heart patient, the electrode configuration having a first baseline impedance measure that is utilized to rate-responsively pace the patient;

stopping rate-responsive pacing that is based on minute ventilation;

automatically switching to a different electrode configuration;

re-establishing a baseline impedance measure that is associated with the different electrode configuration; and

re-starting rate responsive pacing using the different electrode configuration to ascertain minute ventilation.

28. The method of claim 27, wherein said re-establishing the baseline impedance measure comprises doing so after the patient has been at rest for a pre-determined period of time.

29. The method of claim 27, wherein said re-establishing the baseline impedance measure comprises doing so using one or more activity sensors that monitor for a time period during which the patient'"'"'s activity level is appropriate for re-establishing the baseline impedance.

30. The method of claim 27, wherein said re-establishing the baseline impedance measure comprises doing so by adapting a baseline impedance measure over a pre-determined period of time.

31. The method of claim 27, wherein said automatically switching comprises switching to an atrial bipolar configuration.

32. The method of claim 27, wherein said automatically switching comprises switching to a dual unipolar configuration.

33. The method of claim 27, wherein said automatically switching comprises switching to a bipolar configuration.

34. The method of claim 27, wherein said automatically switching comprises switching to a unipolar configuration.

35. The method of claim 27 further comprising storing, in device memory, information that indicates that an electrode configuration switch has taken place.

36. One or more computer-readable media having computer-readable instructions thereon which, when executed by one or more processors of a stimulation device, cause the one or more processors to:

detect a problem associated with an electrode configuration that is being utilized to ascertain minute ventilation for a rate-responsively paced heart patient, the electrode configuration having a first baseline impedance measure that is utilized to rate-responsively pace the patient;

stop rate-responsive pacing that is based on minute ventilation;

automatically switch to a different electrode configuration;

re-establish a baseline impedance measure that is associated with the different electrode configuration; and

re-start rate responsive pacing using the different electrode configuration to ascertain minute ventilation.

37. A stimulation device comprising:

one or more computer-readable media;

multiple electrodes for stimulating and for monitoring minute ventilation;

one or more processors;

instructions stored on the computer-readable media which, when executed by the one or more processors, cause the processors to;

detect a problem associated with an electrode configuration that is being utilized to ascertain minute ventilation for a rate-responsively paced heart patient, the electrode configuration having a first baseline impedance measure that is utilized to rate-responsively pace the patient;

stop rate-responsive pacing that is based on minute ventilation;

automatically switch to a different electrode configuration;

re-establish a baseline impedance measure that is associated with the different electrode configuration; and

re-start rate responsive pacing using the different electrode configuration to ascertain minute ventilation.