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Determination of sample volume adequacy in biosensor devices

  • US 6,797,150 B2
  • Filed: 10/10/2001
  • Issued: 09/28/2004
  • Est. Priority Date: 10/10/2001
  • Status: Expired due to Term
First Claim
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1. A method for determining the volume of a biological sample held within an electrochemical biosensor, comprising:

  • applying an alternating voltage having a selected amplitude and a selected frequency to the biosensor;

    measuring the current generated by applying said alternating voltage;

    determining the capacitance of the biosensor from said measured current;

    determining the surface area of the biosensor in contact with the sample based on said determined capacitance; and

    determining the volume of the sample within the biosensor based on said determined surface area.

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