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Methods for labeling nucleotides, labeled nucleotides and useful intermediates

  • US 6,797,818 B2
  • Filed: 01/14/2002
  • Issued: 09/28/2004
  • Est. Priority Date: 10/08/1996
  • Status: Expired due to Term
First Claim
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1. A labeled nucleotide having formula:

  • embedded imagewherein;

    X represents an aliphatic diamine; and

    the labeling moiety comprises a label and a spacer, wherein the spacer is coupled at one end to the Pt atom and at the other end to the label, the spacer comprising a chain having at least four carbon atoms and at least one oxygen atom in the chain.

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